Federico Maria Sacchetti

PROXIMAL HUMERUS RECONSTRUCTION AFTER TUMOR RESECTION: ENDOPROSTHESIS IMPLANT FOR ELDERLY PATIENTS.

Federico Maria Sacchetti

Humeral reconstruction post tumor resection is a challenging quest. Reconstruction strategies depend first of all on age and general conditions of the patient, fumor dimensions, local invasion and bone quality. Many kinds of surgery are described in literature, mostly megaprosthesis, hemiartoplasty or …

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Electrical impedance spectroscopy signatures of red blood cells and platelets in acute ischemic stroke clots in the Clotbase International Registry: Significance for etiology and first pass effect

Cansu Sahin, Alice Giraud, Nazan Güner Sak, Pierluca Messina et autres

BACKGROUND: Clot composition plays a key role in the pathophysiology of Acute Ischemic Stroke (AIS) and impacts the effectiveness of treatments such as thrombolysis and mechanical thrombectomy (MT). Developing an electrochemical impedance spectroscopy (EIS) based device to identify clot characteristics could improve …

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Balloon angioplasty alone in carotid artery dissections: an overlooked therapeutic choice in acute ischemic stroke

Joe‐Marie Abousleiman, Christophe Cognard, Fabrice Bonneville, Gaultier Marnat et autres

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C-reactive protein expression in acute ischemic stroke blood clots: Implications for etiology

Cansu Sahin, Nazan Güner Sak, Alice Giraud, Pierluca Messina et autres

Abstract Introduction C-reactive protein (CRP) is a prototypic inflammation marker, with elevated levels associated with an increased risk of cerebrovascular events. To determine whether CRP could be a useful biomarker of stroke etiology, we investigated CRP expression in acute ischemic stroke (AIS) …

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O03 Developing an electrical impedance sensor to identify platelet content in acute ischemic stroke clots: results from the ex vivo clotbase international registry

Cansu Sahin, Nazan Güner Sak, Alice Giraud, Pierluca Messina et autres

Introduction Development of a medical device that uses an electrical impedance signature to identify clot characteristics that influence success of treatment could improve stroke patient outcomes. Aim of Study To assess how well electrical impedance platelet signature identified platelet composition of acute …

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1414: Phase II trial SPRINT "Sarcoma Preoperative Radiation with SIB" (NCT05761054) : preliminary results

Daniela Greto, Mauro Loi, Domenico Andrea Campanacci, Federico Maria Sacchetti et autres

Electrical impedance measurements can identify red blood cell–rich content in acute ischemic stroke clots ex vivo associated with first-pass successful recanalization

Cansu Sahin, Alice Giraud, Duaa Jabrah, Smita Patil et autres

Background: Electrochemical impedance spectroscopy can determine characteristics such as cell density, size, and shape. The development of an electrical impedance-based medical device to estimate acute ischemic stroke (AIS) clot characteristics could improve stroke patient outcomes by informing clinical decision making. Objectives: , …

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Tumor size and surgical margins are important prognostic factors of synovial sarcoma - A retrospective study

Federico Maria Sacchetti, Andac Celasun Alsina, Francesco Muratori, Guido Scoccianti et autres

Background: Synovial Sarcoma (SS) is a rare soft tissue sarcoma. Mean time to get a SS diagnosis from the onset of symptoms is 10 years, furthermore, SS is associated with late metastasis. Surgery is the main treatment option, whose quality deeply affects …

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SPRINT trial: Preoperative chemotherapy and IMRT SIB in locally advanced sarcoma.

Daniela Greto, Mauro Loi, Domenico Andrea Campanacci, Andrea Gaetano Allegra et autres

e23548 Background: In Soft Tissue Sarcoma (STS) patients with high risk features, preoperative radiotherapy (RT) associated with anthracyclines-based chemotherapy is delivered to downstage the tumor and improve resectability, although at the expense of increased risk of skin toxicity and wound dehiscence that …

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Return to sports following lower limb musculoskeletal tumor surgery—A systematic review

Metin Tolga Buldu, Federico Maria Sacchetti, Adam T. Yasen, Sherron Furtado et autres

BACKGROUND: Survivors of primary malignant musculoskeletal tumors often face long-term disability. Clinicians at present are unable to provide evidence-based advice about returning to sports, which is important for active patients. PURPOSES: Identify patients returning to sports. Describe the sporting activities in which …

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Surgical treatment for pelvic bone metastatic disease from renal cell carcinoma

Guido Scoccianti, Roberto Scanferla, Maurizio Scorianz, Filippo Frenos et autres

INTRODUCTION: Pelvic bone metastases from renal cell carcinoma (RCC) are challenging due to their destructive pattern, poor response to radiotherapy and hypervascularity. The purpose of our study was to review a series of patients undergoing surgical treatment with the aim to investigate: …

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RETURN TO SPORTS FOLLOWING LOWER LIMB MUSCULOSKELETAL TUMOUR SURGERY: A SYSTEMATIC REVIEW

Metin Tolga Buldu, Federico Maria Sacchetti, Adam T. Yasen, Sherron Furtado et autres

Primary malignant bone and soft tissue tumours often occur in the lower extremities of active individuals including children, teenagers and young adults. Survivors routinely face long-term physical disability. Participation in sports is particularly important for active young people but the impact of …

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