Kun Shu

Aberrant structural-functional connectivity coupling in migraineurs is associated with mental behavioral scores and neurotransmitter

Yan Li, Mei Huang, Kun Shu, Keyang Chen et autres

cn (code pays fourni par la source)

Glymphatic alteration in NAFLD patient: a preliminary magnetic resonance imaging study based on DTI-ALPS

Kun Shu, Shaoqing Chen, Shuang Meng, Yang Yang et autres

OBJECTIVE: This study aims to investigate alterations in glymphatic system (GS) function in patients with non-alcoholic fatty liver disease (NAFLD) and explore the relationship of these alterations with cognition and clinical indicators. MATERIALS AND METHODS: In this cross-sectional study, forty-three patients with …

cn (code pays fourni par la source)

Rational Design of Mono-Substituted Gd-DOTA as Highly Stable and Efficient MRI Contrast Agents for Hepatobiliary and Inflammation Imaging

Yinghui Ding, Xinzhong Ruan, Kun Shu, Weiyuan Xu et autres

Hepatobiliary-specific magnetic resonance imaging contrast agents (MRI CAs) play a crucial role in the early diagnosis of hepatocellular carcinoma (HCC). However, only two acyclic CAs, Gd-BOPTA and Gd-EOB-DTPA, exhibit unfavorable kinetic inertness. Our study focused on the development of superior stable innovative …

cn (code pays fourni par la source)

Altered Brain Glymphatic Function at Diffusion-Tensor MRI in Pre-cirrhotic Metabolic Dysfunction-Associated Fatty Liver Disease

Kun Shu, Yuchuan Fu, Mei Juan Huang, Zheng Cai et autres

cn, fi (code pays fourni par la source)

Chiral Pyclen-Based Heptadentate Chelates as Highly Stable MRI Contrast Agents

Yong Jian, Gengshen Mo, Weiyuan Xu, Yao Liu et autres

In recent years, pyclen-based complexes have attracted a great deal of interest as magnetic resonance imaging (MRI) contrast agents (CAs) and luminescent materials, as well as radiopharmaceuticals. Remarkably, gadopiclenol, a Gd(III) bishydrated complex featuring a pyclen-based heptadentate ligand, received approval as a …

cn, it, es (code pays fourni par la source)

Glymphatic dysfunction in NAFLD patient: A preliminary magnetic resonance imaging study based on DTI-ALPS

Kun Shu, Jiawen Song, Xiaoyan Huang, Xinjian Ye et autres

cn (code pays fourni par la source)

Leveraging artificial intelligence to identify high-risk patients for postoperative sore throat: An observational study

Qiang-Qiang Zhou, Xiaoya Liu, Huifang Yun, Yahong Zhao et autres

Postoperative sore throat (POST) is a prevalent complication after general anesthesia and targeting high-risk patients helps in its prevention. This study developed and validated a machine learning model to predict POST. A total number of 834 patients who underwent general anesthesia with …

cn (code pays fourni par la source)

Chiral Gd-DOTA as a Versatile Platform for Hepatobiliary and Tumor Targeting MRI Contrast Agents

Weiyuan Xu, Xinjian Ye, Min Cong Wu, Xin Sheng Jiang et autres

-based contrast agents (GBCAs) in patients is currently the major safety concern in clinical magnetic resonance imaging (MRI) scans, and the lack of task-specific GBCAs limits its usage in the early detection of disease and imaging of specific biological regions. Herein, ultrastable …

cn, hk (code pays fourni par la source)

Disruption of brain regional homogeneity and functional connectivity in male NAFLD: evidence from a pilot resting-state fMRI study

Kun Shu, Xinjian Ye, Jiawen Song, Xiaoyan Huang et autres

BACKGROUND: The neurophysiological mechanisms underlying cognitive deficits in non-alcoholic fatty liver disease (NAFLD) remain unknown. Cognitive changes may be caused by brain alterations in neural activity and functional connectivity (FC). AIM: This study aims to investigate the alterations between spontaneous brain neural …

cn (code pays fourni par la source)

Rational Design of Gd-DOTA-Type Contrast Agents for Hepatobiliary Magnetic Resonance Imaging

Weiyuan Xu, Yi Lü, Jiao Xu, Huaping Li et autres

The safety risks of gadolinium (Gd 3+ )-based contrast agents (GBCAs) arise from their inevitable leakage of Gd 3+, and the pursuit of more stable GBCAs for magnetic resonance imaging (MRI) has drawn increasing attention. Yet, Gd-EOB-DTPA and Gd-BOPTA are the only …

cn (code pays fourni par la source)

Prediction of Early Mortality Among Children With Moderate or Severe Traumatic Brain Injury Based on a Nomogram Integrating Radiological and Inflammation-Based Biomarkers

Pingyi Zhu, Nimo Mohamed Hussein, Jing Yan Tang, Lu‐Lu Lin et autres

Inflammation-based scores have been increasingly used for prognosis prediction in neurological diseases. This study aimed to investigate the predictive value of inflammation-based scores combined with radiological characteristics in children with moderate or severe traumatic brain injury (MS-TBI). A total of 104 pediatric …

cn (code pays fourni par la source)

Early death prediction in children with traumatic brain injury using computed tomography scoring systems

Nimo Mohamed Hussein, Pingyi Zhu, Shuang Meng, Yu Wang et autres

cn (code pays fourni par la source)