Marc J. van Houwelingen

Haemodynamic determinants of supine hypertension in patients with classical orthostatic hypotension

Amber H. van der Stam, Boriana S. Gagaouzova, Fabian I. Kerkhof, Ineke A. van Rossum et autres

OBJECTIVE: The relation between classical orthostatic hypotension (cOH) and supine hypertension is largely unknown. We investigated the relative contributions of heart rate (HR), stroke volume (SV) and total peripheral resistance (TPR) to supine and upright blood pressure (BP). METHODS: In this retrospective …

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Pathophysiological aspects of carotid sinus massage

J. Gert van Dijk, Boriana S. Gagaouzova, Jelle S Y de Jong, Ineke A. van Rossum et autres

AIMS: We studied the blood pressure (BP) decrease after carotid sinus massage to study cardioinhibition (CI) and arterial vasodepression (aVD), whether CI and aVD occur independent of one another, and how the BP decrease ends. METHODS AND RESULTS: We measured BP, heart …

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Variability of cardioinhibition in vasovagal syncope: differences between subgroups during cardioinhibition and beyond

Ineke A. van Rossum, Frederik J. de Lange, David G. Benditt, Erik W. van Zwet et autres

PURPOSE: We compared hemodynamic parameters between subjects with marked, intermediate and minimal cardioinhibition during vasovagal syncope. METHODS: The study included subjects with a decrease in heart rate while experiencing a complete vasovagal syncope during tilt-table testing. The subjects were classified as having …

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A case showing how hyperventilation may decrease blood pressure in neurogenic orthostatic hypotension

J. Gert van Dijk, Boriana S. Gagaouzova, Marc J. van Houwelingen, Robert H. A. M. Reijntjes et autres

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Novel Methods for Quantification of Vasodepression and Cardioinhibition During Tilt-Induced Vasovagal Syncope

J. Gert van Dijk, Maryam Ghariq, Fabian I. Kerkhof, Robert H. A. M. Reijntjes et autres

Rationale: Assessing the relative contributions of cardioinhibition and vasodepression to the blood pressure (BP) decrease in tilt-induced vasovagal syncope requires methods that reflect BP physiology accurately. Objective: To assess the relative contributions of cardioinhibition and vasodepression to tilt-induced vasovagal syncope using novel …

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Response to “Cardiac output by pulse contour analysis does not match the increase measured by rebreathing during human spaceflight”

Marc J. van Houwelingen, G. J. Langewouters

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A modified device for continuous non-invasive blood pressure measurements in humans under hyperbaric and/or oxygen-enriched conditions.

René van der Bel, B. Sliggers, Marc J. van Houwelingen, Johannes J. van Lieshout et autres

BACKGROUND: It would be desirable to safely and continuously measure blood pressure noninvasively under hyperbaric and/or hyperoxic conditions, in order to explore haemodynamic responses in humans under these conditions. METHODS: A systematic analysis according to 'failure mode and effects analysis' principles of …

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challengeventriculoarterial responses to orthostatic Carotid artery pulse wave time characteristics to

Arnold P.G. Hoeks, Koen D. Reesink, Evelien Hermeling, M. Christianne Hoeberigs et autres

A piezoelectric micro control valve with integrated capacitive sensing for ambulant blood pressure waveform monitoring

Maarten S. Groen, Kai Wu, Robert A. Brookhuis, Marc J. van Houwelingen et autres

We have designed and characterized a MEMS microvalve with built-in capacitive displacement sensing and fitted it with a miniature piezoelectric actuator to achieve active valve control. The integrated displacement sensor enables high bandwidth proportional control of the gas flow through the valve. …

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A MICRO CONTROL VALVE WITH INTEGRATED CAPACITIVE SENSING FOR AMBULANT BLOOD PRESSURE WAVEFORM MONITORING

Maarten S. Groen, Robert A. Brookhuis, Marc J. van Houwelingen, Dannis Michel Brouwer et autres

We have designed and fabricated the first single-wafer proportional micro control valve with built-in capacitive dis-placement sensing. The displacement sensor can facilitate high-speed active proportional control of gas flow through the valve. This is an essential requirement for non-invasive blood pressure waveform …

A novel approach to assess hemorrhagic shock severity using the arterially determined left ventricular isovolumic contraction period

Marc J. van Houwelingen, Daphne Merkus, Jan Hofland, Jan Bakker et autres

Recently, the ventilatory variation in pre-ejection period (ΔPEP) was found to be useful in the prediction of fluid-responsiveness of patients in shock. In the present study we investigated the behavior of the ventilation-induced variations in the systolic timing intervals in response to …

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Initiation of ventricular contraction as reflected in the aortic pressure waveform

Marc J. van Houwelingen, Daphne Merkus, Maaike te Lintel Hekkert, Geert van Dijk et autres

Prior to aortic valve opening, aortic pressure is perturbed by ventricular contraction. The onset of this pressure perturbation coincides with the onset of the left ventricular (LV) isovolumic contraction, and hence will be referred to as the start of the arterially detected …

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