Emmett Tsz Yeung Wong

P4.747: Outcomes of extended criteria deceased donor kidney transplants allocated by Remuzzi scoring of explant biopsies.

Anantharaman Vathsala, Hersharan Kaur Sran, Benjamin Yen-Seow Goh, Emmett Tsz Yeung Wong et autres

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WCN26-1361 LIPID METABOLISM AS A DRIVER OF DIABETIC KIDNEY DISEASE PROGRESSION

Rachel Sze Jen Goh, Hiromi Koh, Emmett Tsz Yeung Wong, C H Sia et autres

Diabetes kidney disease (DKD) is the main cause of kidney failure in Singapore. There remains risks of progression even with existing therapies, hence the impetus to investigate and identify novel biomarkers that may allow for earlier diagnosis, or serve as potential therapeutic …

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Expansion of molecular mismatch scores to guide clinical management of kidney transplant patients

Emmett Tsz Yeung Wong, Chris Wiebe

PURPOSE OF REVIEW: Optimizing outcomes for kidney transplant recipients requires both minimizing premature death related to over-immunosuppression and avoiding alloimmune injury associated with under-immunosuppression. Both of these goals require a precise understanding of the alloimmune risk faced by the recipient. Although the …

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Gazing into the crystal ball of mortality prediction in conservative kidney care

Charmaine Si Min Sia, Jia Neng Tan, Emmett Tsz Yeung Wong

Since Clyde Shields became the first patient with kidney failure to undergo long-term haemodialysis in 1960, the advent of kidney replacement therapy (KRT) has provided a means of organ sustenance and life prolongation for more than 2.7 million patients with chronic kidney …

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HLA molecular mismatch categories revised and validated using updated HLAMatchmaker™ software

Emmett Tsz Yeung Wong, James E. Cooper, Robert Balshaw, Ian W. Gibson et autres

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The impact of HLA genotype imputation on allele determination, eplet mismatch and alloimmune risk categories in a southeast Asian cohort of kidney transplant recipients

Emmett Tsz Yeung Wong, Hersharan Kaur Sran, Mario D’Costa, Zhijie Chang et autres

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Deceased donor kidney transplantation in candidates with pre-transplant hematological malignancies: a literature review and recipient allocation proposal in Singapore

Emmett Tsz Yeung Wong, Ian Tatt Liew, Hein Than, Aloysius Ho et autres

Deceased donor kidneys are a scarce national resource, and principles of utilitarianism and justice govern allocation. Kidney transplant recipients with a prior history of cancer show an increased risk of malignancy- and non-malignancy-related mortality compared to their counterparts without a previous history …

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Intravenous Immunoglobulin as Adjunctive Treatment for BK DNAemia

Matthew R. D’Costa, Anantharaman Vathsala, Emmett Tsz Yeung Wong, Zhijie Chang et autres

Purpose: BK DNAemia (BK-D) remains a challenge for kidney transplant recipients (KTRs), with no proven antiviral treatment. Immunosuppression reduction (ISR) can help clear BK-D but raises the risk of acute rejection (AR). The role of intravenous immunoglobulin (IVIG) in managing BK-D and …

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Comparative Analysis of Computerised Tomography Volumetry vs. Nuclear Imaging (Dimercaptosuccinic Acid) Scan in Predicting Early Post-Donation Renal Function Using Split Renal Function

H.Y. Kek, Wilfred Hing Sang Wong, Lin Kyaw, Jun Lu et autres

Purpose: Evaluating preoperative split renal function (SRF) is vital for donor assessment in living donor kidney transplantation (LDKT). With growing use of volume-based pre-operative assessments, reliance on nuclear-based studies is decreasing. Our study aims to show that volume-based pre-operative assessments are equivalent …

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Microvascular Inflammation Alters the Prognosis Associated with T-Cell-Mediated Rejection

Emmett Tsz Yeung Wong, Robert Balshaw, Ian W. Gibson, Julie Ho et autres

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National Trends of Sex Disparity over 5 Decades of Living Donor Kidney Transplantation in Singapore

Hersharan Kaur Sran, Ho Dang Quy Dung, Ian Tatt Liew, Emmett Tsz Yeung Wong et autres

Purpose: Females are less likely to receive living donor kidney transplantation (LDKT) for end-stage kidney disease (ESKD) compared to males but are more often living donors. It is unknown if these observations persist in societies where gender inequality has improved over time. …

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DMSA-Based Pre-Donation Differential Renal Function Does Not Significantly Impact the New Baseline Glomerular Filtration Rate: A Retrospective Five-Year Cohort Study of 125 Kidney Donors

H.Y. Kek, H.S. Wong, Lin Kyaw, J. Lu et autres

Purpose: Differential renal function is crucial in determining which kidney to select for donor nephrectomy, often with preference given to the less functional kidney after considering anatomical and clinical factors. This study evaluates whether this approach impacts short- and long-term post-donation renal …

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