Gazing into the crystal ball of mortality prediction in conservative kidney care

Le résumé fourni par la source

Since Clyde Shields became the first patient with kidney failure to undergo long-term haemodialysis in 1960, the advent of kidney replacement therapy (KRT) has provided a means of organ sustenance and life prolongation for more than 2.7 million patients with chronic kidney disease (CKD) today.1 In the early days of dialysis, due to resource limitations, this treatment was prioritised for younger patients (defined as aged 25–45) with minimal comorbidities (i.e. “absence of long-standing hypertension and its permanent complications, particularly coronary artery disease and cerebrovascular disease”) and of “value to the community”—as determined by an Admissions Advisory Committee, nicknamed by some then as the “God Squad”.2 Decades later, with advancements in medical science, improvements in dialysis technologies and increased funding support from governments worldwide, dialysis has become widely accessible. Patients considered for dialysis are getting older, multimorbid and increasingly frail.

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