Lasse Boding

Social Inequality in the Uptake of Varicella Vaccination: A Danish Nationwide Observational Study

Anne Cathrine Falch-Jørgensen, Rikke Færgemann Hansen, Natalie Clausen, Mette Boie et autres

AIM: Varicella is a highly contagious disease affecting approximately 90% of children before the age of 10, constituting a substantial health and societal burden. This study investigates the association between socio-demographic and socio-economic factors and uptake of varicella vaccination in Denmark, 2019-2024. …

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Central role of glycosylation processes in human genetic susceptibility to SARS-CoV-2 infections with Omicron variants

Geller Frank, Xiaoping Wu, Vilma Lammi, Erik Abner et autres

The host genetics of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have previously been studied based on cases from the earlier waves of the pandemic in 2020 and 2021, identifying 51 genomic loci associated with infection and/or severity. SARS-CoV-2 has shown rapid …

dk, us, fi, ee (code pays fourni par la source)

EPH216 Social Inequality in the Uptake of Varicella Vaccination: A Danish Nationwide Observational Study

Anne Cathrine Falch-Jørgensen, Lasse Boding

Central role of glycosylation processes in human genetic susceptibility to SARS-CoV-2 infections with Omicron variants

Frank Geller, Xiaoping Wu, Vilma Lammi, Erik Abner et autres

The host genetics of SARS-CoV-2 has previously been studied based on cases from the earlier waves of the pandemic in 2020 and 2021, identifying 51 genomic loci associated with infection and/or severity. SARS-CoV-2 has shown rapid sequence evolution increasing transmissibility, particularly for …

dk, fi, ee, us (code pays fourni par la source)

SARS‐CoV‐2 antibody dynamics over time and risk factors associated with infection and long COVID‐19 symptoms in large working environments

Cecilie Bo Hansen, Kristina Dvoncova, Laura Pérez‐Alós, Kamille Fogh et autres

BACKGROUND: Factors influencing SARS-CoV-2 antibody dynamics, transmission, waning and long COVID-19 symptomatology are still not fully understood. METHODS: In the Danish section of the Novo Nordisk Group, we performed a prospective seroepidemiological study during the first and second waves of the COVID-19 …

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A Review of Major Danish Biobanks: Advantages and Possibilities of Health Research in Denmark

Kristina Laugesen, Jonas Mengel‐From, Kaare Christensen, Jørn Olsen et autres

Biobank research may lead to an improved understanding of disease etiology and advance personalized medicine. Denmark (population ~5.9 million) provides a unique setting for population-based health research. The country is a rich source of biobanks and the universal, tax-funded healthcare system delivers …

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Author Correction: Vitamin D status and severity of COVID-19

Nete Munk Nielsen, Thor Grønborg Junker, Sanne Grundvad Boelt, Arieh Sierra Cohen et autres

“A.A. contributed to the conception and idea of the work. N.M.N., A.S.C., L.B. and A.A. contributed to the design of the study. N.M.N., A.S.C., L.B. S.G.B contributed to the acquisition of data. N.M.N., A.H., L.B., S.G.B and T.G.J. contributed to the analyses …

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Vitamin D status and severity of COVID-19

Nete Munk Nielsen, Thor Grønborg Junker, Sanne Grundvad Boelt, Arieh Sierra Cohen et autres

We explored the association between COVID-19 severity and vitamin D status using information from Danish nation-wide health registers, the COVID-19 surveillance database and stored blood samples from the national biobank. 25-hydroxyvitamin D (25(OH)D) was measured using tandem mass spectroscopy. The association between …

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Optimization and evaluation of a live virus SARS-CoV-2 neutralization assay

Anders Frische, Patrick Terrence Brooks, Mikkel Gybel‐Brask, Susanne Gjørup Sækmose et autres

Virus neutralization assays provide a means to quantitate functional antibody responses that block virus infection. These assays are instrumental in defining vaccine and therapeutic antibody potency, immune evasion by viral variants, and post-infection immunity. Here we describe the development, optimization and evaluation …

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Titration of anti-SARS-CoV-2 monoclonal antibodies and appropriate secondary antibodies for the ELISA

Anders Frische, Patrick Terrence Brooks, Mikkel Gybel‐Brask, Susanne G. Saekmose et autres

Datasættet er licenseret under Creative Commons Attribution 4.0 International License (CC BY)

Neutralizing Antibodies Against the SARS-CoV-2 Omicron Variant (BA.1) 1 to 18 Weeks After the Second and Third Doses of the BNT162b2 mRNA Vaccine

Ria Lassaunière, Charlotta Polacek, Anders Frische, Lasse Boding et autres

This cohort study examines neutralizing antibodies against the SARS-CoV-2 Omicron variant (BA.1) after the second and third doses of the BNT162b2 mRNA vaccine among Danish adults.

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Neutralisation of the SARS-CoV-2 Delta variant sub-lineages AY.4.2 and B.1.617.2 with the mutation E484K by Comirnaty (BNT162b2 mRNA) vaccine-elicited sera, Denmark, 1 to 26 November 2021

Ria Lassaunière, Charlotta Polacek, Jannik Fonager, Marc Bennedbæk et autres

Several factors may account for the recent increased spread of the SARS-CoV-2 Delta sub-lineage AY.4.2 in the United Kingdom, Romania, Poland, and Denmark. We evaluated the sensitivity of AY.4.2 to neutralisation by sera from 30 Comirnaty (BNT162b2 mRNA) vaccine recipients in Denmark …

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