Dejan Jakimovski

Bringing neuroimaging to the bedside: can machine learning empower transcranial sonography?

Maria Marcella Laganà, Giovanni Malferrari, Dejan Jakimovski

jp, it, us (code pays fourni par la source)

Impact of processing and analysis methodology on thalamic susceptibility assessment in multiple sclerosis

Fahad Salman, Niels Bergsland, Michael G. Dwyer, Jack A. Reeves et autres

BACKGROUND: Studies using quantitative susceptibility mapping (QSM) to investigate thalamic iron levels in people with multiple sclerosis (pwMS) have yielded inconsistent results. It has been speculated that cohort differences are responsible for these inconsistencies, leading to the phenomenological "early-rise late-decline" hypothesis, which …

us (code pays fourni par la source)

Paramagnetic rim lesions are associated with choroid plexus inflammation and expansion over 5 years in people with multiple sclerosis

Jack A. Reeves, Ashley Tranquille, Alexander Bartnik, Maryam Mohebbi et autres

BACKGROUND: Chronic active white matter inflammation is linked with multiple sclerosis (MS) clinical severity and is likely integral in MS progression. It has also been associated with choroid plexus (CP) inflammation in vivo, pointing to a potential pathophysiological link between the two …

us (code pays fourni par la source)

Evaluating the role of anti-EBV antibodies as biomarkers for the evolution of multiple sclerosis: A longitudinal study

Mehak Semy, Ashley Tranquille, Niels Bergsland, Dejan Jakimovski et autres

us (code pays fourni par la source)

Sensitivity of Quantitative Susceptibility Mapping for Clinical Research in Deep Gray Matter

Fahad Salman, Abhisri Ramesh, Thomas Jochmann, Mirjam Prayer et autres

Quantitative susceptibility mapping (QSM) is an advanced MRI technique for assessing iron, calcium, and myelin tissue levels based on magnetic susceptibility. QSM consists of multiple processing steps, with various choices for each step. While QSM is increasingly applied in neurodegenerative disease research, …

us, de (code pays fourni par la source)

Quantifying cortical lesions in large legacy multiple sclerosis clinical trial MRI datasets using multi-contrast post-processing and deep learning

Michael G. Dwyer, Niels Bergsland, Alexander Bartnik, Dejan Jakimovski et autres

Abstract Multiple sclerosis (MS) is a chronic neurological disease affecting both white and gray matter of the central nervous system. Despite the well-established history of gray matter involvement in MS, cortical lesions are almost never evaluated in clinical trials because of limitations …

us, nl (code pays fourni par la source)

MRI-specific signature of dementia with Lewy bodies—a step towards improved differential diagnosis of the dementia spectrum

Maria Marcella Laganà, Dejan Jakimovski

us (code pays fourni par la source)

Diffusion- and Tractography-Based Characterization of Tissue Damage Within and Surrounding Paramagnetic Rim Lesions in Multiple Sclerosis

Maryam Mohebbi, Jack A. Reeves, Dejan Jakimovski, Alexander Bartnik et autres

BACKGROUND AND PURPOSE: Paramagnetic rim lesions (PRLs) are an imaging biomarker of chronic inflammation in MS that are associated with more aggressive disease. However, the precise tissue characteristics and extent of their damage, particularly with regard to connected axonal tracts, are incompletely …

us (code pays fourni par la source)

Sensitivity of Quantitative Susceptibility Mapping in Clinical Brain Research.

Fahad Salman, Abhisri Ramesh, Thomas Jochmann, Mirjam Prayer et autres

BACKGROUND: Quantitative susceptibility mapping (QSM) of the brain is an advanced MRI technique for assessing tissue characteristics based on magnetic susceptibility, which varies with the composition of the tissue, such as iron, calcium, and myelin levels. QSM consists of multiple processing steps, …

The relationship between optical coherence tomography and magnetic resonance imaging measurements in people with multiple sclerosis: A systematic review and meta-analysis

Omid Mirmosayyeb, Mohammad Yazdan Panah, Elham Moases Ghaffary, Saeed Vaheb et autres

us, ir (code pays fourni par la source)

Resilience Among Caregivers of People With Multiple Sclerosis: Exploring the Influence of Personality Traits, Coping, and Caregiver Burden

Katelyn S. Kavak, Dejan Jakimovski, Svetlana Primma Eckert, Kara Patrick et autres

Background: Resilience has been recognized as a vital protective factor in coping with stress and adversity. Multiple sclerosis (MS) caregiving is a complex and demanding role, often characterized by challenges. Methods: Caregivers of people with MS were recruited through health care professionals …

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Anatomy-driven segmentation of parafoveal optical coherence tomography (OCT) measures may improve associations with clinical outcomes in multiple sclerosis

Omid Mirmosayyeb, Bianca Weinstock‐Guttman, Robert Zivadinov, Dejan Jakimovski

us (code pays fourni par la source)