Accès ouvert
2025
article
OpenAlex
Rong Yan, Zixin Zhang, Hugo R. de Jonge, Ruxian Lin et autres
ileal and distal colonic/rectal enteroids as a model and the Forskolin Induced Swelling Assay (FIS), we compared CFTR mediated fluid secretion in human enterocytes across the crypt-villus axis. CFTR expression and FIS decreased as enterocytes differentiated from crypt to become partially differentiated …
us, nl
(code pays fourni par la source)
Accès ouvert
2025
preprint
OpenAlex
Rong Yan, Zixin Zhang, Hugo R. de Jonge, Ruxian Lin et autres
ileal and distal colonic/rectal enteroids as a model and the Forskolin Induced Swelling Assay (FIS), we compared CFTR mediated fluid secretion in human enterocytes across the crypt-villus axis. CFTR expression and FIS decreased as enterocytes differentiated from crypt to become partially differentiated …
us, nl
(code pays fourni par la source)
Accès ouvert
2024
article
OpenAlex
Mark Donowitz, Chung-Ming Tse, Rafiq Sarker, Ruxian Lin et autres
Background & Aims Diarrhea occurs in up to 50% of cases of COVID-19. Nonetheless, the pathophysiologic mechanism(s) have not been determined. Methods This was examined using normal human enteroid monolayers exposed apically to live SARS-CoV-2 or non-replicating virus-like particles (VLPs) bearing the …
us
(code pays fourni par la source)
Accès ouvert
2022
preprint
OpenAlex
Ming C. Tse, Yan Rong, Zixin Zhang, Ruxian Lin et autres
Abstract Background and Aims Cholesterol-rich membrane domains, also called lipid rafts (LR), are specialized membrane domains that provide a platform for intracellular signal transduction. Membrane proteins often cluster in LR that further aggregate into larger platform-like structures that are enriched in ceramide …
us
(code pays fourni par la source)