An Industry Perspective on the use of Forced Degradation Studies to Assess Comparability of Biopharmaceuticals
John M. Campbell, Stefano Colombo, Jamie L. Doyle, Dana I. Filoti et autres
us, dk, de, gb (code pays fourni par la source)
Informations fournies par OpenAlex. Research Africa ne déduit ni nationalité, ni poste, ni coordonnées personnelles.
John M. Campbell, Stefano Colombo, Jamie L. Doyle, Dana I. Filoti et autres
us, dk, de, gb (code pays fourni par la source)
Yuping Wei, Hsiang‐Chieh Hung, Fang Sun, Tao Bai et autres
cn, us (code pays fourni par la source)
Thesis (Ph.D.)--University of Washington, 2015
Harihara S. Sundaram, Xia Han, Ann K. Nowinski, Norman D. Brault et autres
It is highly desirable to develop a universal nonfouling coating via a simple one-step dip-coating method. Developing such a universal coating method for a hydrophilic polymer onto a variety of surfaces with hydrophobic and hydrophilic properties is very challenging. This work demonstrates …
us, cn (code pays fourni par la source)
Harihara S. Sundaram, Xia Han, Ann K. Nowinski, Jean‐Rene Ella‐Menye et autres
Zwitterionic sulfobetaine polymers with a catechol chain end (DOPA-PSB) were applied to a variety of hydrophobic polymer sheets and fibers. In addition, a silica surface was tested as a representative hydrophilic substrate. The polymer-coated surfaces showed significantly lower fouling levels than uncoated …
us, cn (code pays fourni par la source)
Fang Sun, Tao Bai, Lei Zhang, Jean‐Rene Ella‐Menye et autres
A new strategy is proposed to sensitively and rapidly detect analytes with weak Raman signals in complex media using surface-enhanced Raman spectroscopy (SERS) via detecting the SERS signal changes of the immobilized probe molecules on SERS-active substrates upon binding of the analytes. …
us (code pays fourni par la source)
Ann K. Nowinski, Andrew Dickson White, Andrew J. Keefe, Shaoyi Jiang
Introduction into the human body makes most nanoparticle systems susceptible to aggregation via nonspecific protein binding. Here, we developed a peptide-capped gold nanoparticle platform that withstands aggregation in undiluted human serum at 37 °C for 24 h. This biocompatible and natural system …
us (code pays fourni par la source)
Andrew Dickson White, Andrew J. Keefe, Jean‐Rene Ella‐Menye, Ann K. Nowinski et autres
Charged amino acids are the most common on surfaces of proteins and understanding the interactions between these charged amino acids, salt bridging, is crucial for understanding protein-protein interactions. Previous simulations have been limited to implicit solvent or fixed binding geometry due to …
us (code pays fourni par la source)
Andrew Dickson White, Andrew J. Keefe, Ann K. Nowinski, Qing Shao et autres
Peptide libraries allow researchers to quickly find hundreds of peptide sequences with a desired property. Currently, the large amount of data generated from peptide libraries is analyzed by hand, where researchers search for repeating patterns in the peptide sequences. Such patterns are …
us (code pays fourni par la source)
Andrew Dickson White, Wenjun Huang, Ann K. Nowinski, Shaoyi Jiang
us (code pays fourni par la source)
Andrew J. Keefe, K. B. Caldwell, Ann K. Nowinski, Andrew Dickson White et autres
us (code pays fourni par la source)
Ann K. Nowinski, Fang Sun, Andrew Dickson White, Andrew J. Keefe et autres
Cysteine is commonly used to attach peptides onto gold surfaces. Here we show that the inclusion of an additional linker with a length of four residues (-PPPPC) and a rigid, hydrophobic nature is a better choice for forming peptide self-assembled monolayers (SAMs) …
us (code pays fourni par la source)
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