Amandine Buffière-Morgado

Characterization of skin Th17 transcriptional profiles in psoriatic patients under adalimumab biotherapy

Amandine Buffière-Morgado, Elodie Couderc, Adriana Delwail, Laure Favot et autres

In psoriasis, a specific cytokine network has been described to play a central role in the pathophysiology of the disease. Anti-cytokine therapeutic approaches have been largely developed and TNFα constitutes the main target. Adalimumab is a human anti-TNFα monoclonal antibody that has …

fr (code pays fourni par la source)

Interleukin-17A-induced production of acute serum amyloid A by keratinocytes contributes to psoriasis pathogenesis

Elodie Couderc, Franck Morel, P. Levillain, Amandine Buffière-Morgado et autres

BACKGROUND: Acute-serum Amyloid A (A-SAA), one of the major acute-phase proteins, is mainly produced in the liver but extra-hepatic synthesis involving the skin has been reported. Its expression is regulated by the transcription factors NF-κB, C/EBPβ, STAT3 activated by proinflammatory cytokines. OBJECTIVES: …

fr (code pays fourni par la source)

Relationship between cutaneous polyarteritis nodosa (cPAN) and macular lymphocytic arteritis (MLA): Blinded histologic assessment of 35 cPAN cases

Amandine Buffière-Morgado, Maxime Battistella, Marie‐Dominique Vignon‐Pennamen, Adèle de Masson et autres

fr (code pays fourni par la source)

Étude de l'effet de l'adalimumab sur le profil cytokinique cutané et sérique de patients atteints de psoriasis

Amandine Buffière-Morgado

Introduction : Les nouvelles biothérapies dont les anti-TNFα (alpha) ont révolutionné le traitement du psoriasis avec une amélioration significative des lésions et une absence de toxicité par rapport aux traitements classiques. Toutefois si la plupart des lésions disparaissent, certaines plaques persistent. L'objectif …

fr (code pays fourni par la source)