Accès ouvert
2025
article
OpenAlex
Sophia Zborowsky, Jérémy Seurat, Quentin Balacheff, Solène Ecomard et autres
The rise of antimicrobial resistance leads to renewed interest in evaluating phage therapy. In murine models highly effective treatment of acute pneumonia caused by Pseudomonas aeruginosa relies on the synergistic antibacterial activity of bacteriophages with neutrophils. Here, we show that depletion of …
fr, us, re
(code pays fourni par la source)
Accès ouvert
2024
article
OpenAlex
Rogelio A. Rodriguez-Gonzalez, Quentin Balacheff, Laurent Debarbieux, Jacopo Marchi et autres
ABSTRACT Infections caused by multidrug resistant (MDR) pathogenic bacteria are a global health threat. Bacteriophages (“phage”) are increasingly used as alternative or last-resort therapeutics to treat patients infected by MDR bacteria. However, the therapeutic outcomes of phage therapy may be limited by …
us, re, fr
(code pays fourni par la source)
Accès ouvert
2024
preprint
OpenAlex
Rogelio A. Rodriguez-Gonzalez, Quentin Balacheff, Laurent Debarbieux, Jacopo Marchi et autres
Infections caused by multi-drug resistant (MDR) pathogenic bacteria are a global health threat. Phage therapy, which uses phage to kill bacterial pathogens, is increasingly used to treat patients infected by MDR bacteria. However, the therapeutic outcome of phage therapy may be limited …
us, re, fr
(code pays fourni par la source)
Accès ouvert
2024
preprint
OpenAlex
Sophia Zborowsky, Jérémy Seurat, Quentin Balacheff, Solène Ecomard et autres
Abstract The rise of antimicrobial resistance has led to renewed interest in evaluating phage therapy. In murine models highly effective treatment of acute pneumonia caused by Pseudomonas aeruginosa relies on the synergistic antibacterial activity of bacteriophages with neutrophils. Here, we show that …
fr, us, re
(code pays fourni par la source)
Accès ouvert
2024
article
OpenAlex
Sophia Zborowsky, Quentin Balacheff, Ioanna Théodorou, Rokhaya Kane et autres
Abstract Bacteriophages (phages) are increasingly considered for both treatment and early detection of bacterial pathogens given their specificity and rapid infection kinetics. Here, we exploit an engineered phage expressing nanoluciferase to detect signals associated with Pseudomonas aeruginosa lysis spanning single cells to …
fr, us
(code pays fourni par la source)
2021
article
OpenAlex
Quentin Balacheff, Jean‐Baptiste Lovato, Benjamin Coiffard, Coralie L’Ollivier et autres
Infections represent one of the leading causes of morbidity and mortality in solid organ transplantation (SOT) recipients. Although Toxocara species are prevalent worldwide, toxocariasis is an important neglected human disease that can manifest as visceral or ocular larva migrans, or covert toxocariasis. …
fr
(code pays fourni par la source)