Accès ouvert
2025
article
OpenAlex
Jarrod P. Kaufman, Jacob Levy, David J. Chen, Yuri W. Novitsky
Abstract Hernia repair remains one of the most common operative procedures performed by general surgeons and herniologists (hernia specialists). Congenital or acquired hernias fall into predictable categories: inguinal, ventral or abdominal, and incisional. Inguinal hernias are the most common accounting for roughly …
us
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Accès ouvert
2024
article
OpenAlex
David G. Armstrong, Dennis Paul Orgill, Robert D. Galiano, Paul M. Glat et autres
As the incidence of diabetic foot ulcers (DFU) increases, better treatments that improve healing should reduce complications of these ulcers including infections and amputations. We conducted a randomized controlled trial comparing outcomes between a novel purified reconstituted bilayer membrane (PRBM) to the …
us
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2023
article
OpenAlex
Nadav Haim, Jarrod P. Kaufman, M. Yu. Gurevich
BACKGROUND: Deep and tunneling wounds are a challenge to apply and maintain most advanced wound dressings to promote effective healing. An autologous whole blood clot is a topical treatment and has been found to be safe and effective in healing cutaneous wounds. …
il, us
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2023
article
OpenAlex
Robert Snyder, Vickie R. Driver, Windy Cole, Warren S. Joseph et autres
The etiology of acute and chronic wounds goes beyond those often reported in the literature, including those with exposed structures, those in which the entire wound bed cannot be visualized, and patients who are not candidates for typical standard of care. Treatment …
us, de
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Accès ouvert
2022
article
OpenAlex
Thomas E Serena, Dennis Paul Orgill, David G. Armstrong, Robert D. Galiano et autres
BACKGROUND: This randomized controlled trial evaluated the safety and effectiveness of weekly and biweekly applications of dehydrated human amnion and chorion allograft (dHACA) plus standard of care compared to standard of care alone on chronic venous leg ulcers. METHODS: This open-label randomized …
us
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2022
article
OpenAlex
Robert Snyder, Vickie R. Driver, Windy Cole, Warren S. Joseph et autres
Complex or hard-to-heal wounds can be acute or chronic; the complexity is based on patient-specific local, systemic, and psychosocial factors. Use of autologous tissue can be a significant adjunct to wound closure. Grafts and flaps are the most common autologous tissue used …
us, de
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Accès ouvert
2021
article
OpenAlex
David G. Armstrong, Dennis Paul Orgill, Robert D. Galiano, Paul M. Glat et autres
Biomaterial engineering has produced numerous matrices for use in tissue repair, utilizing various materials and processing methods, which can impact the ability of the products to encourage wound healing. Recently, we observed favorable clinical outcomes, using a novel purified reconstituted bilayer matrix …
us, ch
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Accès ouvert
2020
article
OpenAlex
David G. Armstrong, Dennis Paul Orgill, Robert D. Galiano, Paul M. Glat et autres
Diabetic foot ulcers (DFUs) have significant clinical impact and carry a substantial economic burden. Patients with DFUs that are refractory to standard wound care are at risk for major complications, including infection and amputation and have an increased risk of mortality. This …
us
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Accès ouvert
2019
article
OpenAlex
Paul M. Glat, Dennis Paul Orgill, Robert D. Galiano, David G. Armstrong et autres
Aseptically processed dehydrated human amnion and chorion allograft (dHACA) (AmnioBand) has shown great promise in the treatment of recalcitrant diabetic foot ulcers (DFUs) when compared with standard wound care but has not yet been compared to any other tissue forms used in …
us, cl
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2019
article
OpenAlex
Grant Vincent Bochicchio, Álvaro García, Jarrod P. Kaufman, Qiao Zhang et autres
BACKGROUND: To our knowledge, there is an absence of prospective randomized multicenter controlled trials evaluating both the impact of technique and mesh type on outcomes in complicated ventral hernia repair. STUDY DESIGN: A prospective randomized multicenter controlled trial of 120 patients at …
us
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Accès ouvert
2018
article
OpenAlex
Lawrence A. DiDomenico, Dennis Paul Orgill, Robert D. Galiano, Thomas E Serena et autres
Amnion and chorion allografts have shown great promise in healing diabetic foot ulcers (DFUs). Results from an interim analysis of 40 patients have demonstrated the accelerated healing ability of a novel aseptically processed, dehydrated human amnion and chorion allograft (dHACA). The goal …
us
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Accès ouvert
2018
article
OpenAlex
Charles M. Zelen, Dennis Paul Orgill, Thomas E Serena, Robert Galiano et autres
Aseptically processed human reticular acellular dermal matrix (HR-ADM) has been previously shown to improve wound closure in 40 diabetic patients with non-healing foot ulcers. The study was extended to 40 additional patients (80 in total) to validate and extend the original findings. …
us
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