Xiaoyan Shen

GALNT2-mediated O-GalNAcylation of METTL3 promotes radioresistance in esophageal squamous cell carcinoma by stabilizing GPX4 mRNA via m6A modification

Chen Chen, Xiaoyan Shen, Dan Xi, Yun Ding et autres

cn (code pays fourni par la source)

A covered liquid bridge structure for the manipulation and self-assembly of small objects

Feng Ma, Xiaoyan Shen, Xiongheng Bian

cn (code pays fourni par la source)

Current advances in restoring intestinal barrier homeostasis by natural medicines

Yihan Wang, Sheng Tan, Jie Huang, Qibiao Wu et autres

mo, kr, cn (code pays fourni par la source)

Reversing chemoresistance in ovarian cancer: network pharmacology reveals how hydroxychloroquine/sulfasalazine duotherapy remodels tumor inflammatory–immune microenvironment

Xin Hong, Xin Wen, Ting Zhang, Yihao Liu et autres

Introduction Chemoresistance is a key contributor of ovarian cancer (OC) mortality. Clinical observations of extended survival in OC patients with rheumatic comorbidities following anti-rheumatic treatment suggest hydroxychloroquine (HCQ) and sulfasalazine (SSZ) could act as chemosensitizers. However, how the HCQ/SSZ combination counteracts platinum–taxane …

us, cn (code pays fourni par la source)

Gynostemma pentaphyllum-derived extracellular vesicles alleviate skin aging by destabilizing STING

Dong Wang, Shaoliang Duan, Yujuan Fan, Tongqing Chen et autres

Skin aging represents a multifaceted degenerative process that predisposes to dermatological pathologies, including infections, dermatitis, and malignancies, causing great physical and psychological distress to patients. Conventional therapies, including topical antioxidants and sunscreens, have shown limited efficacy with safety concerns that continue to …

cn (code pays fourni par la source)

Manipulating metabolism-reprogrammed monocytic-MDSCs prevents colitis-associated dysplasia by IL-10/HIF-1α/DLL4 signaling

Yirui Wang, Jiahui Ni, Guize Feng, Yan You et autres

Dysplasia has been described in various inflammatory environments. However, the mechanisms underlying the dysplastic transformation of the intestinal epithelium and the increased risk of colorectal cancer in colitis patients are not yet fully understood. In this study, we observed that IL-10 was …

ca, cn (code pays fourni par la source)

4,4′-Dimethoxychalcone ameliorates estrogen-deficient osteoporosis by targeting PTP1B to inhibit the c-Src/NFATc1 signaling axis

X Y Han, Mingming Xu, Yongyan Chen, Yuxuan Hao et autres

Postmenopausal osteoporosis (PMOP) is a skeletal disease linked to immune dysregulation, characterized by the overactivation of myeloid-lineage osteoclasts. To address the limitations of current therapies, this study investigated the immunomodulatory potential and molecular mechanism of the natural flavonoid 4,4′-dimethoxychalcone (DMC). Using in …

cn (code pays fourni par la source)

Galactan from the Lactarius hatsudake Tanaka Mycelium: Structural Characterization and in vitro Biological Evaluation

Yiming Zhou, Ying Xiao, Xiaoyan Shen, Yiming Tian et autres

cn, us (code pays fourni par la source)

A covered liquid bridge structure for the manipulation and self-assembly of small objects

Ma Feng, Xiaoyan Shen, Xiongheng Bian

Design, synthesis, and biological evaluation of anthraquinone-isoxazole hybrids as a novel ferroptosis inducer in triple-negative breast cancer

Huaxin Hou, Linfang Lai, Xuyang Chen, Qiuping Zhang et autres

30th Anniversary of Phytomedicine: Looking Back and Forth

Thomas Efferth, Susana Zacchino, Milen I. Georgiev, Rong‐Rong He et autres

de, ar, bg, cn, us, in, qa, tr, ir, pk, Cameroun, hk, pt, mo, es (code pays fourni par la source)

Degradable Scaffold-Mediated Synergistic Matrix Formation by Endogenous Cells: An In Vivo Manufacturing Strategy for Off-the-Shelf Cardiovascular Bypass Grafts to Address Clinical Shortages

Yijie He, Yalan Mo, Xiaoyan Shen, Jialin Xu et autres

cn (code pays fourni par la source)