Mauricio Flores‐Fortis

Loss of miR-122 promotes cell migration and poor prognosis in triple-negative breast cancer treated by neoadjuvant chemotherapy

Mauricio Flores‐Fortis, Isidro X. Perez‐Añorve, Carlos César Patiño-Morales, Ernesto Soto‐Reyes et autres

BACKGROUND: MicroRNAs (miRNAs) are short non-coding RNAs that regulate gene expression post-transcriptionally. miR-122 is abnormally expressed in breast cancer, functioning as both a tumor suppressor and oncomiR, however, its role in triple-negative breast cancer (TNBC) remains unclear. PURPOSE: In this study we …

mx (code pays fourni par la source)

Three-dimensional cell culture conditions promoted the Mesenchymal-Amoeboid Transition in the Triple-Negative Breast Cancer cell line MDA-MB-231

Daniela Rodríguez-Cruz, Aleix Boquet-Pujadas, Eunice López-Muñoz, Ruth Rincón-Heredia et autres

Introduction Breast cancer (BC) is the leading cause of death among women, primarily due to its potential for metastasis. As BC progresses, the extracellular matrix (ECM) produces more type-I collagen, resulting in increased stiffness. This alteration influences cellular behaviors such as migration, …

mx, fr, ch (code pays fourni par la source)

Integrated Transcriptome Analysis of Radioresistant Cells Revealed Genes and Pathways Predictive Of Tumor Response to Radiotherapy and Chemotherapy in Breast Cancer

Isidro X. Perez‐Añorve, Mauricio Flores‐Fortis, Carlos César Patiño-Morales, Elizabeth Ortiz-Gutiérrez et autres

Abstract Breast cancer cells exposed to radiotherapy frequently develop radiation resistance through molecular and phenotypic changes. While there is evidences of pathways controlling radioresistance, the evolution of diverse cell phenotypes and transcriptional changes as mediators of radioresistance in breast cancer are restricted. …

mx (code pays fourni par la source)

Molecular Characterization of Patients with Cryptorchidism: Preliminary Search for an Expression Profile Related to That of Testicular Germ-Cell Tumors

Fabiola García-Andrade, Rosa María Vigueras‐Villaseñor, Margarita Chávez‐Saldaña, Julio César Rojas‐Castañeda et autres

Cryptorchidism (CO) is a risk factor for the development of testicular germ-cell tumors (TGCT). This is supported by reports showing the persistence of gonocytes in CO patients. These cells are proposed to be related to the development of germ-cell neoplasia in situ …

mx (code pays fourni par la source)

Transcriptomic profiles‐based approach to decode the role of miR ‐122 in triple negative breast cancer

Mauricio Flores‐Fortis, Isidro X. Perez Añorve, Oscar Del Moral Hernández, Nicolás Villegas‐Sepúlveda et autres

miR-122 has been considered both as tumor suppressor miRNA and oncomiR in breast tumor phenotypes. However, the role of miR-122 in triple-negative breast cancer (TNBC) is still unknown. In this study, the clinical value of miR-122 was used to describe the transcriptomic …

mx (code pays fourni par la source)

Identification of miRNAs progressively deregulated in the biological model of gastric carcinogenesis

Sergio Ayala-Diaz, Joaquín Manzo-Merino, Rosario Morales-Espinosa, Mauricio Flores‐Fortis et autres

mx, co (code pays fourni par la source)

Deciphering the epigenetic network in cancer radioresistance

Ariana Cabrera‐Licona, Isidro X. Perez‐Añorve, Mauricio Flores‐Fortis, Óscar Del Moral-Hernández et autres

mx (code pays fourni par la source)