Ting Yang

Chronic Hypobaric Hypoxia at High Altitudes Aggravates Chronic Obstructive Pulmonary Disease in Mice

Yuhang Huang, Xiancheng Hei, Xiang Fu, Linxi Ma et autres

Objective: Chronic obstructive pulmonary disease (COPD) is the third leading cause of death worldwide. However, the effects of chronic hypobaric hypoxia on COPD in high-altitude areas remain controversial. This study aimed to evaluate the impact of chronic hypobaric hypoxia on COPD in …

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Cardiopulmonary Exercise Testing and Pulmonary Function for Assessing Chronic Obstructive Pulmonary Disease

Chunyan Yu, Yong Li, Shiwei Qumu, Jingen Xia et autres

Purpose: To compare the grading concordance between pulmonary function tests (PFTs) and cardiopulmonary exercise testing (CPET) in grading chronic obstructive pulmonary disease (COPD) and to guide the clinical application of CPET in appropriate patient populations. Patients and Methods: A retrospective analysis was …

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Impact of the POPulation Medicine Multimorbidity Intervention in Xishui County (POPMIX) on suspected asthma patients: protocol for the POPMIX-Asthma cluster-randomized controlled trial

Zhoutao Zheng, Yingchi Luo, Lirui Jiao, X. R. Lyu et autres

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Cardiopulmonary Exercise Testing and Quantitative Chest CT in COPD: The Stronger Association of Emphysema Over Airway Thickness with Functional Impairment

Yaodie Peng, Minghui Shi, Chunyan Yu, Ting Yang et autres

Introduction: The relationship between cardiopulmonary function and chest structure, particularly the square root of wall area of a hypothetical airway with a luminal perimeter of 10 mm (Pi10), in patients with chronic obstructive pulmonary disease (COPD) remains unclear. This study aims to …

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Validation of the Chinese version of Morningness-Eveningness Questionnaire for screening delayed sleep-wake phase disorder with bipolar disorder among Han Chinese population

Ting Yang, Yongen Lin, Tong Li, Zhaoyu Gan

Objective: Delayed sleep-wake phase disorder (DSWPD) is commonly seen in bipolar disorder (BD). However, valid screening tools for DSWPD have not been available, especially in China. Therefore, this study aimed to explore the validation of the Morningness-Eveningness Questionnaire (MEQ) for screening DSWPD …

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Impact of the POPulation Medicine Multimorbidity Intervention in Xishui County (POPMIX) on suspected asthma patients: protocol for the POPMIX-Asthma cluster-randomized controlled trial

Ke Huang, Xunliang Tong, Xingyao Tang, Yuhao Liu et autres

BACKGROUND: Asthma is a common chronic disease responsible for a considerable disease burden in China and around the world. Despite its burden, there is substantial unmet need for asthma care, including screening, diagnosis, treatment, and management. Symptom-based screening for asthma could support …

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Association of genetic predisposition to dyslipidemia and physical activity with incident dementia

Yumei Liang, Siqi Xie, Dandan Sheng, Lan Ding et autres

INTRODUCTION: The association between genetic predisposition to dyslipidemia and dementia risk is inconsistent. It remains unknown whether a physically active lifestyle is associated with a lower dementia risk across different levels of this genetic predisposition. METHODS: We analyzed 198,448 White participants (aged …

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Development and Validation of An Interpretable Machine Learning Model for Identifying COPD in Population with High Cardiovascular Risk: A Multicenter Study

Kaifang Meng, Xinran Zhang, Ke Huang, MD Chaoqun Wu et autres

Impact of the Population Medicine Multimorbidity Intervention in Xishui County (POPMIX) on People at High Risk for Chronic Obstructive Pulmonary Disease Who Experience Mental Health Symptoms: Protocol for the POPMIX-MH Cluster Randomized Controlled Trial

Wenjin Chen, Shiyu Zhang, Ying-ping Wang, Zhoutao Zheng et autres

BACKGROUND: Chronic obstructive pulmonary disease (COPD) and mental health conditions represent intersecting public health challenges, especially in resource-limited rural China. Existing care models often neglect the psychosocial needs of populations at high risk for COPD, resulting in limited effectiveness of prevention and …

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[Therapy of follicular lymphoma associated bronchiolitis obliterans with lung transplantation: 2 cases and literature review].

Ying Cai, Yun Chao Su, S Y Wang, M S W Qumu et autres

BO associated with lymphoma and PNP/PAMS, or with lymphoma alone, carries a poor prognosis. LT may represent a viable and safe therapeutic option for selected patients with end-stage BO provided that the underlying lymphoma and PNP/PAMS are well-controlled. LT could improve quality …

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Salivary gland organoids and the future of modeling autoimmune epithelitis in Sjögren’s disease

Ting Yang, Negaar Goudarzi, Frans G. M. Kroese, Xavier Mariette et autres

Sjögren's disease (SjD) is a systemic autoimmune disorder characterized by a striking tropism for epithelial tissues, particularly the salivary and lacrimal glands. Lack of function of the salivary glands (SGs) leads to a panoply of symptoms, dramatically reducing patient quality of life. …

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Unraveling Biomimetic Hydrogen Bonds of Dinucleotides by a Crown‐Ether‐Functionalized Tetraphenylethene‐Based Cage

Fan Cao, Zhimin Cao, Nuojin Yao, Ting Yang et autres

Abstract Natural biological systems achieve precise recognition and regulation of nucleic acids through multi‐domain synergistic interactions. Herein, we report the design and synthesis of a crown‐ether‐functionalized tetraphenylethene‐based cage ( 1 •8X, X = PF 6 ˉ or Clˉ) with two distinct recognition …

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