Takashi Maki

Non-immunoglobulin E-mediated gastrointestinal food allergies in children with Down syndrome: An epidemiological study

Fumiko Okazaki, Hiroyuki Wakiguchi, Yuno Korenaga, Mototsugu Shimokawa et autres

Background Non-immunoglobulin E-mediated gastrointestinal food allergies (non-IgE-GI-FAs) in children with Down syndrome (DS) tend to be more severe, with some children presenting with sepsis-like symptoms. However, the epidemiology of this condition remains unknown. This study aimed to investigate the prevalence rate and …

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Visualization of the Internal Thoracic Arteries in Giant Cell Arteritis on 18F-FDG Semiconductor PET/CT

Takashi Maki, Yohji Matsusaka, Ryota Egi, Akira Seto et autres

ABSTRACT: A 72-year-old woman presented with the fever and the pain of skull and face for 2 weeks. 18 F-FDG PET/CT equipped with semiconductor detectors revealed strong uptake not only in the temporal, cervical, subclavian arteries, and aorta, but also in the …

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Cattle Identification and Activity Recognition by Surveillance Camera

Haike Guan, Naoki Motohashi, Takashi Maki, Toshifumi Yamaai

In cattle farm, it is important to monitor activity of cattle to know their health condition and prevent accidents. Sensors were used by conventional methods to recognize activity of cattle, but attachment of sensors to the animal may cause stress. Camera was …

Erythema Nodosum Masking Kawasaki Disease with an Initial Manifestation of Skin Lesions

Seigo Okada, Yuichi Ishikawa, Maiko Shimomura, Shinpei Sunagawa et autres

We report the first case demonstrating an association between Kawasaki disease (KD) and erythema nodosum (EN).A 3-year-old girl presented with EN as an initial manifestation of KD.At the initial visit, she showed high fever of 40°C, injection of the oropharynx, cervical lymphadenopathy, …

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5. Interchangeable Unit Digital Camera System

Takashi Maki, Takayoshi Shimizu, Kazuhiro Yoshida, Ryohta Kaga

SV40 Infection Associated With Rituximab Treatment After Kidney Transplantation in Nonhuman Primates

Takashi Maki, Angela Carville, Isaac E. Stillman, Kanetoshi Sato et autres

BACKGROUND: A regimen consisting of polyclonal anti-T-cell antibody, sirolimus (SRL), and donor bone marrow (DBM) infusion induces robust transplantation tolerance to skin allografts in mice. We investigated the effect of a similar regimen in a nonhuman primate (NHP) model. METHODS: Cynomolgus macaques …

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Strategies to Induce Marked Prolongation of Secondary Skin Allograft Survival in Alloantigen-Primed Mice

Keisuke Minamimura, Koichiro Sato, Hideo Yagita∥, Toshiyuki Tanaka et autres

Alloreactive memory T cells mediate accelerated rejection. We investigated the effect of polyclonal anti-T-cell antibody (ALS) and rapamycin (RAPA) on skin allograft survival in naïve or alloantigen-primed mice. ALS prolonged graft survival in both naïve and alloantigen-primed mice. T-cell depletion by ALS …

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OX40 Controls Functionally Different T Cell Subsets and Their Resistance to Depletion Therapy

Alexander Kroemer, Xiang Xiao, Minh Diem Vu, Wenda Gao et autres

T cell depletion is a widely used approach in clinical transplantation. However, not all T cells are equally sensitive to depletion therapies and a significant fraction of T cells persists even after aggressive treatment. The functional attributes of such T cells and …

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Role of Stromal-Derived Factor-1α in the Induction of Circulating CD34+CXCR4+ Progenitor Cells After Cardiac Surgery

Shigetoshi Mieno, Basel Ramlawi, Munir Boodhwani, Richard Clements et autres

BACKGROUND: Cardioplegia and cardiopulmonary bypass (CP/CPB) leads to an increase in circulating progenitor cells. The role of stromal-derived factor-1alpha (SDF-1alpha), a key regulator of progenitor cell mobilization, and other cytokines in this process is not clear. METHODS AND RESULTS: Peripheral blood (n=24), …

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福岡大学病院におけるNutrition Support Team (NST)の現況 : NST導入とその成果

Takafumi Maekawa, Hidetoshi Kaneoka, Kiyomi HIDEHIRA, Masaki Kubota et autres

CD4+ Regulatory T Cells Are Spared from Deletion by Antilymphocyte Serum, a Polyclonal Anti-T Cell Antibody

Keisuke Minamimura, Wenda Gao, Takashi Maki

Broad T cell depletion has been used as an integral part of treatment in transplantation and autoimmune diseases. Following depletion, residual T cells undergo homeostatic proliferation and convert to memory-like T cells. In this study, we investigated the effect of T cell …

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Prevention and Cure of Autoimmune Diabetes in Nonobese Diabetic Mice by Continuous Administration of FTY720

Takashi Maki, Rita Gottschalk, Norihiko Ogawa, Anthony P. Monaco

BACKGROUND: Treatment of nonobese diabetic (NOD) mice with FTY720 before the development of insulitis prevents the onset of diabetes. In this study, the authors investigated whether FTY720 treatment of NOD mice with established insulitis prevents the development of diabetes. METHODS: FTY720 (1 …

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