Haris Mumtaz Malik

Bruton Tyrosine Kinase Inhibitor-Based Therapy Versus Rituximab-Containing Regimens for Chronic Lymphocytic Leukemia: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Sadia Yousaf, Maryam Akhtar, Uswah Ilyas, Maham Fatima et autres

Bevacizumab Plus Re-irradiation Therapy vs. Bevacizumab Monotherapy in the Treatment of Recurrent Glioblastomas: A Systematic Review and Meta-analysis (P10-6.009)

Beenish Sabir, Haris Mumtaz Malik, Abdullah Bin Kamran, Amina Khan et autres

This study evaluates the efficacy of re-irradiation combined with bevacizumab compared to bevacizumab alone in treating recurrent glioblastoma.

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Stereotactic body radiotherapy versus non-SBRT radiotherapy for medically inoperable stage I non–small cell lung cancer in elderly patients: A systematic review and meta-analysis.

FNU Sawaira, Aizaz Anwar Khalid, Owais Gul, Muhammad Waqas et autres

e20038 Background: Elderly patients with medically inoperable stage I non–small cell lung cancer (NSCLC) are commonly treated with radiation therapy. While stereotactic body radiotherapy (SBRT) is widely used, its benefits compared with conventional and hypofractionated radiotherapy in this population remain debated. We …

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Early versus delayed laparoscopic appendectomy for acute uncomplicated appendicitis in adults: a systematic review and meta-analysis

Iftikhar Hussain Khan, Soban Ali Qasim, Haris Mumtaz Malik, Muhammad Hamza et autres

BACKGROUND: The optimal timing of laparoscopic appendectomy for acute uncomplicated appendicitis remains uncertain. We performed a systematic review and meta-analysis to compare operative and safety outcomes following early versus delayed laparoscopic appendectomy in adults. METHODS: PubMed, Cochrane Central, and ClinicalTrials.gov were searched …

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Efficacy and safety of dapsone in adult immune thrombocytopenia: a systematic review and meta-analysis

Iftikhar Mohammad Khan, Soban Ali Qasim, Shree Rath, Haris Mumtaz Malik et autres

BACKGROUND: Immune thrombocytopenia (ITP) is an autoimmune condition often managed with corticosteroids, intravenous immunoglobulins, or thrombopoietin receptor agonists. In settings where these therapies are inaccessible or contraindicated, dapsone an older antimicrobial agent with immunomodulatory effects has been proposed as an alternative, though …

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S316 Efficacy and Safety of Sintilimab (PD-1 Inhibitor) Combined With Anti-VEGF Therapy as Neoadjuvant Treatment in Colorectal Cancer: A Systematic Review and Proportional Meta-Analysis

Haris Mumtaz Malik, Beenish Sabir, Adnan Bhat, Waseem Nabi et autres

Introduction: Restorative proctocolectomy with ileal pouch-anal anastomosis (IPAA) is the gold-standard surgical treatment for ulcerative colitis and familial adenomatous polyposis. While IPAA preserves continence and avoids a permanent stoma, it carries risks such as pouchitis and pouch failure. Pelvic radiation, used for …

S1059 Efficacy and Safety of Tislelizumab in Esophageal Squamous Cell Carcinoma: A Proportionality Meta-Analysis

Haris Mumtaz Malik, Arun Kumar Maloth, Adnan Bhat, Muhammad Ansab et autres

Introduction: Tislelizumab, a humanized anti–programmed cell death protein 1 monoclonal antibody, has shown promising antitumor activity in esophageal squamous cell carcinoma (ESCC), a malignancy with poor prognosis and limited therapeutic options. While individual studies report variable outcomes, a comprehensive meta-analysis quantifying its …

PULMONARY LYMPHANGIOLEIOMYOMATOSIS (LAM) HAVING NO EXTRA-PULMONARY MANIFESTATIONS WITH CHEMICAL AND MECHANICAL PLEURODESIS: A CASE REPORT AND REVIEW OF LITERATURE

DR.ANUM IJAZ, Anurag Jha, Muhammad Nabeel Saddique, Mustafa Shehzad et autres

Knowledge, Attitude, and Practices toward Skin Cancer Prevention and Detection among Students of Rawalpindi Medical University: A Cross- Sectional Study

Beenish Sabir, Areeba, M. Ali Babar, Haris Mumtaz Malik et autres

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Efficacy of neoadjuvant combination immune checkpoint inhibitor therapy in patients with resectable high grade melanomas: A systematic review and meta analysis of randomised control trials.

Shariq Ahmad Wani, Mir Wajid Majeed, Paweł Marek Łajczak, Ayesha Ayesha et autres

e21512 Background: The standard treatment for resectable, macroscopic stage 3 melanoma is Surgery followed by adjuvant therapy but neoadjuvant combination immune checkpoint inhibitor(ICI) therapy has shown to significantly increase the survival of patients. This proportional systematic review and metaanalysis aims to evaluate …

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Comparative safety and efficacy of tislelizumab with or without chemotherapy versus chemotherapy alone in patients with lung cancer: A systematic review and meta-analysis.

Aman Ullah, Faseeh Haider, Adnan Bhat, Vatsal Makhija et autres

e20593 Background: Tislelizumab, an anti-PD-1 antibody, is emerging as a promising immunotherapy agent and has demonstrated clinical benefit and acceptable tolerability in recent lung cancer trials. This study aims to assess the safety and efficacy of Tislelizumab, as monotherapy or combined with …

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Busulfan and cyclophosphamide vs busulfan and fludarabine for myeloablation in the patients of acute myeloid leukaemia/ myelodysplastic syndrome undergoing stem cell transplant: A systematic review and meta-analysis.

Haris Mumtaz Malik, Ramzan Hassan Farooq, Faraz Ali, Beenish Sabir et autres

e18545 Background: Acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) are key indications for hematopoietic stem cell transplantation (HSCT). While the Busulfan-Cyclophosphamide (BuCy) regimen has been a standard, it carries high risks of hepatic veno-occlusive disease (HVOD) and non-relapse mortality (NRM), especially …

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