Kyle W. Binder

The unipotent tropical fundamental group

Kyle W. Binder, Eric Katz

Abstract We prove that the unipotent completion of the fundamental group of the generic fiber of a tropically smooth family of algebraic varieties can be computed combinatorially: it is canonically isomorphic to the unipotent tropical fundamental group of its tropicalization, a concept …

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The Singular Cohomology Ring of a Matroid

Kyle W. Binder

We introduce the singular cohomology ring of a matroid which extends the Chow ring of a matroid. This is defined as the singular cohomology ring of a certain quasi-projective toric variety associated to the matroid. Using the matroidal flips of Adiprasito, Huh, …

Mechanisms of antigen-induced reversal of CNS inflammation in experimental demyelinating disease

Jian Li, Lisen Lu, Kyle W. Binder, Jian Xiong et autres

Autoimmune central nervous system (CNS) demyelinating diseases are a major public health burden and poorly controlled by current immunosuppressants. More precise immunotherapies with higher efficacy and fewer side effects are sought. We investigated the effectiveness and mechanism of an injectable myelin-based antigenic …

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BK virus-specific T cells for immunotherapy of progressive multifocal leukoencephalopathy: an open-label, single-cohort pilot study

Irene C. M. Cortese, Erin Beck, Omar Al‐Louzi, Joan M. Ohayon et autres

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Defective glycosylation and multisystem abnormalities characterize the primary immunodeficiency XMEN disease

Juan C. Ravell, Mami Matsuda‐Lennikov, Samuel D. Chauvin, Juan Zou et autres

X-linked immunodeficiency with magnesium defect, EBV infection, and neoplasia (XMEN) disease are caused by deficiency of the magnesium transporter 1 (MAGT1) gene. We studied 23 patients with XMEN, 8 of whom were EBV naive. We observed lymphadenopathy (LAD), cytopenias, liver disease, cavum …

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Limit Sets and Internal Transitivity in Free Group Actions

Kyle W. Binder, Jonathan Meddaugh

It has been recently shown that, under appropriate hypotheses, the $ω$-limit sets of a dynamical system are characterized by internal chain transitivity. In this paper, we examine generalizations of these ideas in the context of the action of a finitely generated free …

In Situ Bioprinting of Autologous Skin Cells Accelerates Wound Healing of Extensive Excisional Full-Thickness Wounds

Mohammed Albanna, Kyle W. Binder, Sean V. Murphy, Jae Hyun Kim et autres

The early treatment and rapid closure of acute or chronic wounds is essential for normal healing and prevention of hypertrophic scarring. The use of split thickness autografts is often limited by the availability of a suitable area of healthy donor skin to …

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Human Skin Bioprinting

Kyle W. Binder, Aleksander Skardal

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List of Contributors

Mohammad Z. Albanna, B. Lynn Allen‐Hoffmann, Abdalla Awidi, Kyle W. Binder et autres

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Hybrid printing of mechanically and biologically improved constructs for cartilage tissue engineering applications

Tao Xu, Kyle W. Binder, Mohammad Z. Albanna, Dennis D. Dice et autres

Bioprinting is an emerging technique used to fabricate viable, 3D tissue constructs through the precise deposition of cells and hydrogels in a layer-by-layer fashion. Despite the ability to mimic the native properties of tissue, printed 3D constructs that are composed of naturally-derived …

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Regenerative Medicine as Applied to General Surgery

Giuseppe Orlando, Kathryn J. Wood, Paolo De Coppi, Pedro M. Baptista et autres

The present review illustrates the state of the art of regenerative medicine (RM) as applied to surgical diseases and demonstrates that this field has the potential to address some of the unmet needs in surgery. RM is a multidisciplinary field whose purpose …

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DROP-ON-DEMAND INKJET BIOPRINTING: A PRIMER

Kyle W. Binder, ARTHUR J. ALLEN, James J. Yoo, Anthony Atala

Engineering complex biological structures for regenerative medicine, in vitro tissue analysis, and pharmaceutical testing require new fabrication techniques that can place specific cells in specific target locations. Conventional cell seeding methods cannot achieve this level of spatial resolution. Biofabrication is a rapidly …

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