Christine Eckhardt

Out-of-hospital cardiac arrest: A 10-year analysis of survival and neurological outcomes

Daniel Schwaiger, Armin Krösbacher, Christine Eckhardt, Lukas Schausberger et autres

Background Out-of-hospital cardiac arrest (OHCA) is a major public health issue with low survival rates. Objective Identification of predictors for survival and good neurological outcomes following OHCA. Methods This retrospective study included all OHCA patients between January 2014 and December 2023. Data …

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Organ Utilization From Donors Following Extracorporeal Cardiopulmonary Resuscitation: A Systematic Review of Graft and Recipient Outcome

Saša Rajšić, Benedikt Treml, Christopher Rugg, Nicole Innerhofer et autres

BACKGROUND: The global shortage of solid organs for transplantation is exacerbated by high demand, resulting in organ deficits and steadily growing waiting lists. Diverse strategies have been established to address this issue and enhance organ availability, including the use of organs from …

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Lebensqualität nach innerklinischem Herz-Kreislauf-Stillstand

Benedikt Treml, Christine Eckhardt, Christoph Oberleitner, Thomas Ploner et autres

BACKGROUND: Cardiac arrest is a life-threatening condition requiring urgent medical care and is one of the leading causes of death worldwide. Given that in-hospital cardiac arrest (IHCA) is still poorly investigated, data on health-associated quality of life thereafter remains scarce. The available …

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Association of anti‐factor Xa‐guided anticoagulation with hemorrhage during ECMO support: A systematic review and meta‐analysis

Saša Rajšić, Robert Breitkopf, Benedikt Treml, Dragana Jadzic et autres

BACKGROUND: The use of extracorporeal membrane oxygenation (ECMO) is associated with complex hemostatic changes. Systemic anticoagulation is initiated to prevent clotting in the ECMO system, but this comes with an increased risk of bleeding. Evidence on the use of anti-Xa-guided monitoring to …

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Organ Donation from Patients Receiving Extracorporeal Membrane Oxygenation: A Systematic Review

Saša Rajšić, Benedikt Treml, Nicole Innerhofer, Christine Eckhardt et autres

OBJECTIVE: The mismatch between the demand for and supply of organs for transplantation is steadily growing. Various strategies have been incorporated to improve the availability of organs, including organ use from patients receiving extracorporeal membrane oxygenation (ECMO) at the time of death. …

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ECMO in Myocardial Infarction-Associated Cardiogenic Shock: Blood Biomarkers as Predictors of Mortality

Thomas Senoner, Benedikt Treml, Robert Breitkopf, Ulvi Cenk Oezpeker et autres

Background: Veno-arterial extracorporeal membrane oxygenation (va-ECMO) can provide circulatory and respiratory support in patients with cardiogenic shock. The main aim of this work was to investigate the association of blood biomarkers with mortality in patients with myocardial infarction needing va-ECMO support. Methods: …

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Development and Validation of a Prognostic Model to Predict Overall Survival in Multiple System Atrophy

Sabine Eschlboeck, Christine Eckhardt, Alessandra Fanciulli, Cecilia Raccagni et autres

Background: Multiple system atrophy (MSA) is a devastating disease characterized by a variable combination of motor and autonomic symptoms. Previous studies identified numerous clinical factors to be associated with shorter survival. Objective: To enable personalized patient counseling, we aimed at developing a …

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Monoclonal antibodies against CGRP (R): non-responders and switchers: real world data from an austrian case series

Katharina Kaltseis, Vera Filippi, Florian Frank, Christine Eckhardt et autres

OBJECTIVE: Assessement of the responder and non-responder rate to consecutive monoclonal CGRP-antibody (CGRP-mAb) treatment, the presence of side effects, analysis of predictors of response and loss-of-effectiveness evaluation over time. METHODS: We conducted a retrospective analysis including 171 patients with episodic (EM) or …

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Analysis of sleep, daytime sleepiness, and autonomic function in multiple system atrophy and Parkinson disease: a prospective study

Christine Eckhardt, Alessandra Fanciulli, Birgit Högl, Anna Heidbreder et autres

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Monoclonal Antibodies Against CGRP (R): Non-responders and Switchers: Real World Data from a Large Case Series

Katharina Kaltseis, Vera Filippi, Florian Frank, Christine Eckhardt et autres

Abstract ObjectiveAssessement of the responder and non-responder rate to consecutive monoclonal CGRP-antibody (CGRP-mAb) treatment, the presence of side effects, analysis of predictors of response and loss of efficacy evaluation over time. Methods We conducted a retrospective analysis including 171 patients with episodic …

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Cardiac sympathetic innervation in Parkinson’s disease versus multiple system atrophy

Christine Eckhardt, Florian Krismer, Eveline Donnemiller, Sabine Eschlböck et autres

Abstract Purpose The aims of this study were to evaluate the diagnostic accuracy of the dual imaging method combining cardiac iodine- 123 -metaiodobenzylguanidine single-photon emission computed tomography combined with low-dose chest computed tomography compared to routine cardiac scintigraphy, and assess regional differences …

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Physiological Assessment of Delirium Severity: The Electroencephalographic Confusion Assessment Method Severity Score (E-CAM-S).

Meike van Sleuwen, Haoqi Sun, Christine Eckhardt, Anudeepthi Neelagiri et autres

OBJECTIVES: Delirium is a common and frequently underdiagnosed complication in acutely hospitalized patients, and its severity is associated with worse clinical outcomes. We propose a physiologically based method to quantify delirium severity as a tool that can help close this diagnostic gap: …

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