Hassiba Oubraham

OUTCOMES AND HEALING PROCESS OF RETINAL PIGMENT EPITHELIAL TEARS IN AMD PATIENTS: A 5-YEAR RETROSPECTIVE OBSERVATIONAL CASE SERIES

Héla Sassi, Alexandra Mière, Hassiba Oubraham, Desire Kaoudio et autres

PURPOSE: To evaluate the incidence of retinal pigment epithelium (RPE) remodeling after RPE tears in age-related macular degeneration (AMD) and assess its association with visual outcomes over a 5-year follow-up. METHODS: This retrospective observational study reviewed AMD eyes with RPE tears and …

fr (code pays fourni par la source)

SPECTRUM: Early clinical experience from the first global real-world study of aflibercept 8 mg in patients with diabetic macular oedema

Clare Bailey, Marion Ronit Munk, Varun Chaudhary, Clemens Lange et autres

The PHOTON Phase 2/3 trial demonstrated the efficacy and safety of intravitreal aflibercept 8 mg in the treatment of diabetic macular oedema (DME) [ 1 ]. SPECTRUM is a global study evaluating aflibercept 8 mg treatment of DME and neovascular age-related macular …

gb, us, ch, ca, de, it, au, dk, fi, fr (code pays fourni par la source)

SPECTRUM: Week 24 data for aflibercept 8 mg indicate improvements in patients with treatment-naïve nAMD and stable outcomes in patients with previously treated nAMD

Andreas Stahl, Clemens Lange, Clare Bailey, Vasileios Efstathios Konidaris et autres

Purpose: To present Week (W) 24 results from the SPECTRUM study on the real-world effectiveness and safety of aflibercept 8 mg in patients with treatment-naïve (TN) and previously treated (PT) neovascular age-related macular degeneration (nAMD). Methods: SPECTRUM (NCT06075147) is an ongoing, [for …

de, gb, ca, it, ch (code pays fourni par la source)

SPECTRUM: early clinical experience from the first global real-world study of aflibercept 8 mg in patients with neovascular age-related macular degeneration

Clare Bailey, Clemens Lange, Varun Chaudhary, Paolo Lanzetta et autres

The CANDELA and PULSAR trials demonstrated the efficacy and safety of intravitreal aflibercept 8 mg in the treatment of neovascular age-related macular degeneration (nAMD) [ 1 , 2 ]. SPECTRUM is the first global real-world study of aflibercept 8 mg in nAMD, …

gb, de, ca, it, ch, us (code pays fourni par la source)

Infographic: SPECTRUM: study design of the global real-world study of aflibercept 8 mg in the treatment of neovascular age-related macular degeneration and diabetic macular edema

Clare Bailey, Clemens Lange, Marion Rohit Munk, Paolo Lanzetta et autres

The authors acknowledge Anshul Tank, PharmD, an employee of Bayer, for medical writing support for the development of this infographic, in accordance with Good Publication Practice guidelines ( https://www.acpjournals.org/doi/10.7326/M22-1460 ). The authors would also like to acknowledge the principal investigators of the …

gb, de, us, ch, it, ca, au, dk, fi, fr (code pays fourni par la source)

Recommandations pour l’utilisation raisonnée des nouvelles molécules anti-VEGF

Catherine P Creuzot-Garcher, Bahram Bodaghi, Salomon Yves Cohen, François Devin et autres

fr (code pays fourni par la source)

Approche diagnostique et parcours thérapeutique de la dégénérescence maculaire liée à l’âge de type atrophique : recommandations de la Fédération France Macula

Vittorio Capuano, Oudy Semoun, A Combes, Carl-Joe Mehanna et autres

Atrophic age-related macular degeneration (AMD) represents a detrimental progression of age-related maculopathy, characterized by advanced retinal lesions associated with drusen and pseudodrusen as well as alterations in the outer retinal layers and RPE. It is characterized by a thinning of the neuroretinal …

fr (code pays fourni par la source)

Final 4-year results of the RAINBOW real-world study: intravitreal aflibercept dosing regimens in France in treatment-naïve patients with neovascular age-related macular degeneration

Salomon Yves Cohen, Marcel Domínguez, Florence Coscas, Céline Faure et autres

PURPOSE: The purpose of this study is to evaluate real-world treatment outcomes in patients with neovascular age-related macular degeneration (nAMD) treated with intravitreal aflibercept (IVT-AFL) in routine clinical practice in France. METHODS: RAINBOW (NCT02279537) was an ambispective, observational, 4-year study assessing IVT-AFL …

fr (code pays fourni par la source)

Two-year outcomes of the APOLLON observational study of intravitreal aflibercept monotherapy in France in patients with diabetic macular edema

Jean‐François Korobelnik, Vincent Daïen, Céline Faure, Ramin Tadayoni et autres

APOLLON (NCT02924311) was a prospective observational study to evaluate the effectiveness of intravitreal aflibercept (IVT-AFL) treatment of diabetic macular edema (DME) over 24 months in routine clinical practice in France. The primary endpoint was mean change from baseline in best-corrected visual acuity …

fr, mq (code pays fourni par la source)

ASSESSMENT OF EARLY CHANGES IN SPECTRAL DOMAIN-OPTICAL COHERENCE TOMOGRAPHY AFTER INITIATION OF TREATMENT WITH INTRAVITREAL AFLIBERCEPT (EYLEA) OVER A 12-WEEK PERIOD FOR PATIENTS WITH NEOVASCULAR AGE-RELATED MACULAR DEGENERATION

Jean‐François Korobelnik, Eric H. Souied, Hassiba Oubraham, Sam Razavi et autres

PURPOSE: To assess early changes in spectral-domain optical coherence tomography during the loading phase with intravitreal aflibercept therapy in patients with neovascular age-related macular degeneration. METHODS: In this prospective, open-label, single-arm, multicenter study, patients with neovascular age-related macular degeneration, who were antivascular …

fr, ch (code pays fourni par la source)

Avis d’experts : actualisation des bonnes pratiques des injections intravitréennes. Recommandations de la Société française d’ophtalmologie et de la Société française d’hygiène hospitalière

Salomon Yves Cohen, Laurent Kodjikian, François Devin, Marie‐Noëlle Delyfer et autres

HAL is a multi-disciplinary open access archive for the deposit and dissemination of scientific research documents, whether they are published or not.The documents may come from teaching and research institutions in France or abroad, or from public

fr (code pays fourni par la source)

Long-term follow up or macular neovascularization using optical coherence tomography angiography: Pro Re Nata versus Treat&Extend regimens

Pierre Sustronck, Alexandra Mière, Hassiba Oubraham, Eric H. Souied

fr (code pays fourni par la source)