Xiaosi Hong

Visceral adipose stem cell–derived small extracellular vesicles inhibit EMT in renal tubular epithelial cells and attenuate diabetic kidney fibrosis

Junyan Yu, Xiaosi Hong, Tianxin Zhu, Jiabin Lin et autres

cn (code pays fourni par la source)

Effects of adiposity, insulin resistance, and inflammation on cardiometabolic multimorbidity: insights from interaction analyses and metabolic phenotyping in the China health and retirement longitudinal study 2011–2018

Lili You, Wenbo Zhao, Meiguang Zheng, Xiaosi Hong et autres

BACKGROUND: Cardiometabolic multimorbidity (CMM) burdens aging populations. Obesity drives CMM via insulin resistance and inflammation, but their nonlinear and combined effects remain unclear. We elucidated how these factors contribute to CMM incidence. METHODS: From CHARLS 2011 to 2018, 6,510 participants were enrolled. …

cn (code pays fourni par la source)

Effects of adiposity, insulin resistance, and inflammation on cardiometabolic multimorbidity: insights from interaction analyses and metabolic phenotyping in the China health and retirement longitudinal study 2011–2018

Lili You, Wenbo Zhao, Meiguang Zheng, Xiaosi Hong et autres

Abstract Background Cardiometabolic multimorbidity (CMM) burdens aging populations. Obesity drives CMM via insulin resistance and inflammation, but their nonlinear and combined effects remain unclear. We elucidated how these factors contribute to CMM incidence. Methods From CHARLS 2011 to 2018, 6,510 participants were …

cn (code pays fourni par la source)

Effects of adiposity, insulin resistance, and inflammation on cardiometabolic multimorbidity: insights from interaction analyses and metabolic phenotyping in the China health and retirement longitudinal study 2011–2018

Lili You, Wenbo Zhao, Meiguang Zheng, Xiaosi Hong et autres

Abstract Background Cardiometabolic multimorbidity (CMM) burdens aging populations. Obesity drives CMM via insulin resistance and inflammation, but their nonlinear and combined effects remain unclear. We elucidated how these factors contribute to CMM incidence. Methods From CHARLS 2011 to 2018, 6,510 participants were …

cn (code pays fourni par la source)

Additional file 1 of Effects of adiposity, insulin resistance, and inflammation on cardiometabolic multimorbidity: insights from interaction analyses and metabolic phenotyping in the China health and retirement longitudinal study 2011–2018

Lili You, Wenbo Zhao, Meiguang Zheng, Xiaosi Hong et autres

Supplementary Material 1

cn (code pays fourni par la source)

Additional file 1 of Effects of adiposity, insulin resistance, and inflammation on cardiometabolic multimorbidity: insights from interaction analyses and metabolic phenotyping in the China health and retirement longitudinal study 2011–2018

Lili You, Wenbo Zhao, Meiguang Zheng, Xiaosi Hong et autres

Supplementary Material 1

cn (code pays fourni par la source)

Association of Resting Pulse Rate with Incident Cardiometabolic Multimorbidity in Middle-Aged and Older Chinese Adults: A Prospective Cohort Study from CHARLS 2011 - 2018

Wenpeng Li, Dongfang Tang, Xiaosi Hong, Meiguang Zheng et autres

cn (code pays fourni par la source)

Galectin-3-integrin α5β1 phase separation disrupted by advanced glycation end-products impairs diabetic wound healing in rodents

Zhongyu Zhang, Zhengde Zhao, Xiuyi Huang, Lifang Zhou et autres

Diabetic foot ulcers are severe diabetic complications, and promoting impaired angiogenesis is essential for wound healing. Pro-angiogenic galectin-3 is elevated in diabetic serum and promotes systemic insulin resistance that may impair wound healing. However, the exact role of galectin-3 in the regulation …

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YTHDF2 regulates ACSL4-dependent ferroptosis of keratinocytes in diabetic wound healing

Liangyan Wu, Lanlan Li, Wei Wang, Sifan Chen et autres

Delayed diabetic wound healing is a global health issue with unclear pathogenesis. Ferroptosis, a form of cell death involving iron and lipid peroxidation, may contribute to delayed diabetic wound. This study investigates the role of ferroptosis in diabetic wound keratinocytes. We measured …

cn (code pays fourni par la source)

The Diminution of R‐Loops Generated by LncRNA DSP‐AS1 Inhibits DSP Gene Transcription to Impede the Re‐Epithelialization During Diabetic Wound Healing

Chen Yang, Hong Lian, Hengli Luo, Chenlin Song et autres

Re-epithelialization constitutes a critical stage in the intricate process of wound healing, yet its mechanisms in the context of diabetic wounds remain elusive. In this study, the role of the mesenchymal-epithelial transition (MET) vis-à-vis the epithelial-mesenchymal transition (EMT) of keratinocytes in diabetic …

cn, us (code pays fourni par la source)

Extracellular vesicle-associated miR-ERIA exerts the anti-angiogenic effect of macrophages in diabetic wound healing

Tingting Zeng, Kan Sun, Lifang Mai, Xiaosi Hong et autres

Many cell types are involved in the regulation of cutaneous wound healing in diabetes. Clarifying the mechanism of cell-cell interactions is important for identifying therapeutic targets for diabetic cutaneous ulcers. The function of vascular endothelial cells in the cutaneous microenvironment is critical, …

Extracellular vesicle-associated miR-ERIA exerts the anti-angiogenic effect of macrophages in diabetic wound healing

Tingting Zeng, Kan Sun, Lifang Mai, Xiaosi Hong et autres

Many cell types are involved in the regulation of cutaneous wound healing in diabetes. Clarifying the mechanism of cell-cell interactions is important for identifying therapeutic targets for diabetic cutaneous ulcers. The function of vascular endothelial cells in the cutaneous microenvironment is critical, …