Ingvild Odsbu

Diagnostic pathways, healthcare utilization, and mortality in children and young people with early onset substance use disorders: a nationwide registry-based cohort study

Štěpánka Ptáčková, Svetlana Skurtveit, Roman Gabrhelík, Ingvild Odsbu et autres

Longitudinal, population-based evidence on the clinical profiles and mortality of youth with substance use disorders (SUDs) is limited, despite significant health and social risks. This study aimed to (1) characterize initial SUD diagnoses, demographic and healthcare profiles, and diagnostic trajectories, and (2) …

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Metformin, antibiotics, painkillers, and proton pump inhibitors shape the gut microbiome, including microbial signatures associated with colorectal neoplasia

Elin Sandertun Karstad, Einar Elvbakken Birkeland, Ekaterina Avershina, Edoardo Botteri et autres

Abstract Background Evidence indicates that commonly prescribed drugs can alter gut microbiome composition in the short term, whereas their long-term effects remain poorly understood. Understanding these drug–microbiome interactions is important for a wide range of gut-related diseases, including colorectal cancer (CRC), and …

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Incidence of ADHD diagnoses and medication initiation among children and adolescents in Norway from 2016-2024

Saima Orangzeb, Ingeborg Hartz, Inger Johanne Bakken, Ingvild Odsbu et autres

Global trends show an increase in ADHD diagnoses and medication use. This study aimed to describe the incidence of ADHD among children and adolescents in Norway from 2016 to 2024, and to investigate sociodemographic factors associated with treatment initiation among newly diagnosed …

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Socioeconomic Position and Somatic Comorbidity in Mental Disorders

Martin Tesli, Vidar Hjellvik, Simon Lergenmuller, Gabriela Hjell et autres

INTRODUCTION: Individuals with mental disorders face an elevated risk for somatic noncommunicable diseases (NCD), such as cardiovascular disease (CVDs), chronic obstructive pulmonary disease (COPD), diabetes, and cancer. Low socioeconomic position (SEP) is linked to both mental disorders and somatic NCDs, but its …

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Predicting future mortality risk in first-episode psychosis: External validation of the MIRACLE-FEP machine learning model

Jukka Saarikivi, Vidar Hjellvik, Jari Tiihonen, Markku Lähteenvuo et autres

BACKGROUND: Identifying patients with first-episode psychosis (FEP) at high mortality risk may facilitate personalized treatment regimen development and reduce the mortality gap between individuals with psychotic disorders and the general population. Following validation studies in Sweden and Finland, we aimed to externally …

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Risk and cause of overdose death after exposure to dispensed opioid analgesics

Ellen Johanna Amundsen, Svetlana Ondrasova Skurtveit, Ingvild Odsbu

Aims: Overdose deaths have been increasing in parts of Europe, including Norway, where opioid analgesics have been the leading cause since 2016. This study quantifies the risk of overdose death following exposure to dispensed opioid analgesics, stratified by sex and age, and …

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Factors associated with changes in opioid analgesic prescribing after opioid agonist treatment initiation: A nationwide registry cohort study

Gabriela Rolová, Svetlana Ondrasova Skurtveit, Anne Bukten, Ingvild Odsbu et autres

Background: Pain is common among individuals receiving opioid agonist treatment (OAT). This study aims to investigate factors associated with changes in opioid analgesic dispensing among treatment-naïve patients initiating OAT. Methods: We analyzed nationwide health and dispensing records of patients initiating OAT (N …

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Migrants and the treatment gap for mental health problems

Lars Johan Hauge, Svetlana Ondrasova Skurtveit, Thomas Sevenius Nilsen, Signe Smith Jervelund et autres

The main goal of the project is to uncover potential inequalities in access to, and treatment for, mental health problems among migrants compared with non-migrants in Norway. Specifically, the project aims to 1) assess whether there is an excess mental health treatment …

A comparison between individuals who died of intentional versus accidental overdoses

Svetlana Ondrasova Skurtveit, Rebecca S. McDonald, Marte Handal, Aleksi Hamina et autres

Målet med studien var å beskrive forskjeller mellom narkotikautløste dødsfall som følge av intensjonelle overdoser (selvmord) og utilsiktet overdoser i Norge. Studien var en registerkoblingsstudie som omfattet seks nasjonale helse- og populasjonsregistre. I løpet av studieperioden fra 2011 til 2019 ble det …

Incidence of and Determinants for Substance Use Disorders Among Individuals With Long‐Term Prescription Opioid Use: A Population‐Based Cohort Study

Håkon Høydal Nestvold, Eirik Haarr, Aleksi Hamina, Vidar Hjellvik et autres

PURPOSE: To assess the incidence of substance use disorders (SUDs) after long-term prescription opioid use (LTOU) and to identify socioeconomic and clinical risk factors associated with SUD among individuals with LTOU. METHODS: Cohort study using linked nationwide registers (2011-2019). We identified 114 …

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Trends in opioid prescribing in Scandinavian countries from 2010 to 2023: Insights from multi‐metric evaluation

Gabriela Rolová, Svetlana Ondrasova Skurtveit, Marte Handal, Geana Paula Kurita et autres

AIMS: Monitoring opioid prescribing across different healthcare systems is essential to understanding population-level exposure and informing global health policies. This study examined opioid utilization in Scandinavian countries between 2010 and 2023 using multiple complementary metrics, addressing the limitations of single-metric comparisons. METHODS: …

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Reply to the Chen and Chen

Gabriela Rolová, Anders Engeland, Line Kynemund Pedersen, Ingvild Odsbu et autres

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