Katharina Keppel

Metallothioneins 1 and 2 Modulate Inflammation and Support Remodeling in Ischemic Cardiomyopathy in Mice

Georg Daniel Duerr, Daniela Dewald, Eva Janine Schmitz, Luise Verfuerth et autres

Aims. Repetitive brief ischemia and reperfusion (I/R) is associated with left ventricular dysfunction during development of ischemic cardiomyopathy. We investigated the role of zinc-donor proteins metallothionein MT1 and MT2 in a closed-chest murine model of I/R. Methods. Daily 15-minute LAD-occlusion was performed …

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CB2 receptor-mediated effects of pro-inflammatory macrophages influence survival of cardiomyocytes

Jan C. Heinemann, Georg Daniel Duerr, Katharina Keppel, Martin Breitbach et autres

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Impaired border zone formation and adverse remodeling after reperfused myocardial infarction in cannabinoid CB2 receptor deficient mice

Georg Daniel Duerr, Jan C. Heinemann, Christopher Gestrich, Tobias Heuft et autres

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