Ian M. Fearon

A Narrative Review of the Potential Impact of Next-Generation Tobacco and Nicotine Products on Cardiovascular Health

Ian M. Fearon, Matthew Stevenson, Thomas Nahde

Cigarette smoking is a cause of serious disease in smokers, including cardiovascular disease (CVD). The processes underpinning the development of CVD are well understood. These involve many cell types and cellular processes contributing to the development of atherosclerotic plaques in blood vessels, …

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An Assessment of the Provision of Vaping Products by UK Stop Smoking Services Using Data From Freedom of Information Requests

Ian M. Fearon, Jordan Millar, John Dunne, M J Murphy

Introduction Cigarette smoking is the leading cause of preventable death and disease and arises due to prolonged and repeated inhalational exposure to chemical toxicants found in cigarette smoke. Within this context, vaping products, also termed e‑cigarettes or electronic nicotine delivery systems, have …

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Chemical Analysis of Aerosol from ElfBar Elfa Pod System Vaping Products Compared with Cigarette Smoke and Regulatory Safety Limits

Ian M. Fearon, Sairah Salim-Sartoni, Zhichao Chen, Yudan Yang et autres

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Indoor Air Quality Assessment During the Use of Tobacco and Nicotine Products*

Peter Wilkinson, Anna Clarke, Ian M. Fearon, Ronan Barry

SUMMARY Chemical toxicants released into the environment during the use of tobacco and nicotine products potentially give rise to an elevated health risk among non-users. The aim of this study was to assess the levels of a wide range of chemical toxicants …

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Topography Study of the glo™ Heated Tobacco Product

Tiffany A Parms, Robert G. Underly, Gary M. Dull, Ian M. Fearon et autres

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Why We Need Greater, Not Less, Access to Reduced-Risk Nicotine Products

Ian M. Fearon

Cigarette smoking is the leading preventable cause of death and disease. Prolonged and repeated inhalational exposure to the chemical toxicants found in cigarette smoke is a known cause of cardiovascular disease, chronic lung disease, and cancer. Novel nicotine products, including e‑cigarettes and …

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Assessment of heated herbal products’ tobacco harm reduction potential: pre‐clinical and clinical studies

Alvaro-Flavio Marinas-Lacasta, Ian M. Fearon, Matthew Stevenson, Tasnim Abusalem et autres

Data from pre-clinical and clinical studies form part of an integrated assessment of the tobacco harm reduction (THR) potential of novel products that may act as cigarette alternatives for adult smokers. We report data from pre-clinical (emissions chemistry and in vitro toxicology) …

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Flavoured Vaping Products in Tobacco Harm Reduction: A Regulatory Perspective

Ian M. Fearon, Matthew Stevenson, Thomas Nahde

Reducing the harms associated with cigarette smoking is a global public health priority. Both the individual‑ and population‑level health impacts of smoking can be reduced by novel products which deliver nicotine, but the use of which decreases user exposure to the harmful …

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Chemical Analysis of Aerosol from ElfBar Elfa Pod System Vaping Products Compared with Cigarette Smoke and Regulatory Safety Limits

Ian M. Fearon, Sairah Sartoni, Zhichao Chen, Yudan Yang

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Abuse Liability Assessment of the RELX Infinity ® Electronic Nicotine Delivery System Among Adult Smokers and Electronic Nicotine Delivery System Users

Donald W. Graff, Ian M. Fearon, Mark McClean, Rebeca Melara et autres

Summary Rationale Nicotine pharmacokinetics and subjective effects are important factors in assessing the abuse liability of tobacco products such as electronic nicotine delivery systems (ENDS). In addition, an abuse liability determination is informative in assessing the ability of ENDS to support switching …

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Emissions from conventional and electronic waterpipes relative to cigarettes and a heated tobacco product

Peter Wilkinson, Anna Clarke, Ian M. Fearon, Ronan Barry

Harms associated with the use of smoked tobacco products, including waterpipes, are due to inhalational exposure to toxicants either present in tobacco or formed during the process of combustion. We assessed levels of 37 toxicants in aerosol emissions from conventional waterpipe heated …

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The effects of electronic cigarette use patterns on health-related symptom burden and quality of life: analysis of US prospective longitudinal cohort study data

Yue Cao, Xuxi Zhang, Ian M. Fearon, Jiaxuan Li et autres

Objective: This study aimed to examine the association between e-cigarette (EC) use patterns and health-related symptoms (fatigue, pain, and emotional problems) as well as general quality of life (QoL). Methods: Data were analyzed from 7,225 adults across Waves 1-6 of the US …

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