Accès ouvert
2026
article
OpenAlex
Catarina Aluai‐Cunha, Ana Couto, Diana Oliveira, Liliana Leite-Martins et autres
Mast cell tumours (MCT) represent one of the most relevant oncologic diseases in veterinary medicine, due to their high incidence, significant impact on clinical decision-making and patient outcomes. Therapeutic options remain limited, thereby reinforcing the critical need to identify additional oncogenic drivers, …
pt
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Accès ouvert
2025
article
OpenAlex
Catarina Aluai‐Cunha, Diana Magalhaes de Oliveira, Hugo Gregório, Gonçalo N. Petrucci et autres
Mast cell tumours (MCT) are the most common cutaneous neoplasms in dogs, with variable behaviours and patient survival time. Both indolent and aggressive forms have been described, but much remains to be explored regarding prognosis and therapy. Evidence has highlighted the influence …
pt
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Accès ouvert
2024
article
OpenAlex
M.P.C. Ribeiro, Ana Canadas‐Sousa, Catarina Aluai‐Cunha, Andreia Alexandra Ferreira Santos
Mast cell tumours (MCTs) are the most frequent cutaneous neoplasia of the dog, and they have very variable biological behaviour and survival times. Surgery is still the best treatment, and despite the several adjuvant therapies described, many cases are very aggressive and …
pt
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Accès ouvert
2023
article
OpenAlex
Catarina Aluai‐Cunha, Catarina Alves Pinto, Alexandra Correia, Cláudia R. Serra et autres
Cancer is a substantial global health problem both in humans and animals with a consistent increase in mortality and incidence rate. The commensal microbiota has been involved in the regulation of several physiological and pathological processes, both within the gastrointestinal system and …
pt
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2023
article
OpenAlex
Catarina Alves Pinto, Catarina Aluai‐Cunha, Andreia Alexandra Ferreira Santos
Currently, the most progressively occurring incident cancer is melanoma. The mouse is the most popular model in human melanoma research given its various benefits as a laboratory animal. Nevertheless, unlike humans, mice do not develop melanoma spontaneously, so they need to be …
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Accès ouvert
2022
article
OpenAlex
Catarina Aluai‐Cunha, Augusto de Matos, Irina Amorim, Fátima Carvalho et autres
As in humans, the prevalence of tumors in companion animals is increasing dramatically and there is a strong need for research on new pharmacological agents particularly for the treatment of those tumors that are resistant to conventional chemotherapy agents such as soft …
pt
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