Alberto Lombardini

Multi-modal refinement of the human heart atlas during the first gestational trimester

Christopher De Bono, Yichi Xu, Samina Kausar, Marine Herbane et autres

Forty first-trimester human hearts were studied to lay groundwork for further studies of the mechanisms underlying congenital heart defects. We first sampled 49,227 cardiac nuclei from three fetuses at 8.6, 9.0, and 10.7 post-conceptional weeks (pcw) for single-nucleus RNA sequencing, enabling the …

fr, cn (code pays fourni par la source)

Multi-modal refinement of the human heart atlas during the first gestational trimester

Christopher De Bono, Yichi Xu, Samina Kausar, Marine Herbane et autres

1. Abstract Forty first-trimester human hearts were studied to lay groundwork for further studies of principles underlying congenital heart defects. We first sampled 49,227 cardiac nuclei from three fetuses at 8.6, 9.0, and 10.7 post-conceptional weeks (pcw) for single-nucleus RNA sequencing, enabling …

us, fr, cn (code pays fourni par la source)

Malignant Insulinoma with Multiple Liver Metastases and Hypercalcitoninemia in a Patient with Type 2 Diabetes Mellitus Presenting as Recurrent Episodes of Diaphoresis due to Severe Hypoglycemia

Marco Ciacciarelli, Gianluca Caruso, Marco Rengo, Piero Maceroni et autres

Insulinoma is an insulin-producing pancreatic neuroendocrine tumor that can be malignant in about 10% of cases. Locoregional invasion, lymph node metastases, or remote metastases are the main criteria of malignant insulinoma. Its incidence in patients with pre-existing diabetes mellitus (DM) is exceptionally …

it (code pays fourni par la source)

A rare case of palatin tonsillar metastasis from small cell lung cancer

Chiara D’Antonio, Alberto Lombardini, Concetta Elisa Onesti, Rosa Maria Falcone et autres

Tonsillar metastases are absolutely rare. Small cell lung cancer (SCLC) is known to be the most frequent histological type of tonsillar metastases, however the way of tumor cells spreading to tonsil remains controversial. We described a case report of 76-year-old man with …

it (code pays fourni par la source)

MTHFR C677T gene polymorphisms and susceptibility to cardiovascular adverse events in metastatic colorectal cancer treated with chemotherapy plus bevacizumab.

Chiara D’Antonio, Adriana Romiti, Alberto Lombardini, Valeria Durante et autres

it (code pays fourni par la source)