Gianluca Caruso

Psoriasis induced by first‑line pembrolizumab in metastatic non‑small cell lung cancer: A case report

Federica Gatti, Gianluca Caruso, Concetta Potenza, Daniele Santini et autres

Therapeutic options for non-small cell lung cancer (NSCLC) have changed with the introduction of immune checkpoint inhibitors. Immunotherapy is generally well tolerated, but can also be associated with severe adverse events, such as the development of new autoimmune diseases. In patients without …

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Rheumatoid Arthritis with Generalized Lymphadenopathy Mimicking Lymphoma on Positron Emission Tomography/Computed Tomography with 18F-Fluorodeoxyglucose

Luca Filippi, Gianluca Caruso, Oreste Bagni, Marco Ciacciarelli et autres

A 42-year-old male presented with weight loss and progressively increasing pain and swelling in joints over the past 3 months. Contrast-enhanced computed tomography (CT) demonstrated pleuropulmonary opacities and supra/infradiaphragmatic lymph nodes enlargement. Positron emission tomography (PET/CT) with 18 F-fluorodeoxyglucose showed intensely increased …

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T1 Bladder Cancer: Comparison of the Prognostic Impact of Two Substaging Systems on Disease Recurrence and Progression and Suggestion of a Novel Nomogram

Anastasios D. Asimakopoulos, Gaia Colalillo, Rossana Telesca, Alessandro Mauriello et autres

Background: The T1 substaging of bladder cancer (BCa) potentially impacts disease progression. The objective of the study was to compare the prognostic accuracy of two substaging systems on the recurrence and progression of primary pathologic T1 (pT1) BCa and to test a …

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Acute pancreatitis secondary to non-functioning pancreatic neuroendocrine tumor: uncommon clinical presentation. Clinical case and review of literature.

Alessandro De Cesare, Annalisa Romina Di Filippo, Gianluca Caruso, Martina Spaziani et autres

BACKGROUND: Pancreatic neuroendocrine tumors (PNETs) are uncommon, representing <5% of all pancreatic neoplasms, divided into functioning PNETs with secreted hormone cause of specific symptoms, and non-functioning PNETs (nf- PNETs) characterized by delayed diagnosis with metastases and clinical manifestations of compressive effects. Surgical …

A rare case of omental extra-gastrointestinal stromal tumor showing two coexisting mutations on exon 14 of the PDGFRA gene

Gianluca Caruso, Luca Pacini, Angelo Iossa, Claudio Di Cristofano et autres

Gastrointestinal stromal tumors (GISTs) are neoplasms arising from mesenchymal cells localized into the muscularis propria of the gastrointestinal (GI) tract [1]; 5% of GISTs are extra-GISTs (EGISTs), as they differently originate from adipose tissue adjacent to the GI tract (omentum and mesentery) …

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Malignant Insulinoma with Multiple Liver Metastases and Hypercalcitoninemia in a Patient with Type 2 Diabetes Mellitus Presenting as Recurrent Episodes of Diaphoresis due to Severe Hypoglycemia

Marco Ciacciarelli, Gianluca Caruso, Marco Rengo, Piero Maceroni et autres

Insulinoma is an insulin-producing pancreatic neuroendocrine tumor that can be malignant in about 10% of cases. Locoregional invasion, lymph node metastases, or remote metastases are the main criteria of malignant insulinoma. Its incidence in patients with pre-existing diabetes mellitus (DM) is exceptionally …

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Non-antibiotic prophylaxis in thyroid surgery. Experience of a single Institution and revision of literature.

Erasmo Spaziani, Annalisa Romina Di Filippo, Claudio Di Cristofano, Gianluca Caruso et autres

AIM: To evaluate the incidence of SSI and systemic infectious complications in a consecutive series of patients undergoing thyroid surgery in the absence of prophylactic antibiotic (NO-AP). METHODS: Prospective observational study including 77 patients who underwent total thyroidectomy and completion of previous …