Marie‐Odile Jauberteau

Specific serum and skin immunological profiles of patients with bullous pemphigoid requiring biologics

Salomé Fourmound, Stéphanie Dumonteil, Hussein Akil, Damien Audevard et autres

Bullous pemphigoid mainly affects older people with various comorbidities. The disease has a high mortality rate due to the disease itself and to the side effects of systemic treatments. The aim of this study was to identify blood and skin predictive factors …

Maroc, fr (code pays fourni par la source)

New proteomic signature in circulating extracellular vesicles from tumor-draining and peripheral veins of patients with lung adenocarcinoma

Jérémy Tricard, Stéphanie Durand, Amandine Rovini, Amy Gateau et autres

fr, ca (code pays fourni par la source)

Extracellular vesicles from type-2 macrophages increase the survival of chronic lymphocytic leukemia cells ex vivo

I.A. Lea, N. Ratti, Stéphanie Durand, Rémy Formento et autres

The resistance of Chronic Lymphocytic Leukemia (CLL) B-cells to cell death is mainly attributed to interactions within their microenvironment, where they interact with various types of cells. Within this microenvironment, CLL-B-cells produce and bind cytokines, growth factors, and extracellular vesicles (EVs). In …

fr (code pays fourni par la source)

Targeting the NTSR2/TrkB oncogenic pathway in chronic lymphocytic leukemia

I.A. Lea, May Yassine, Boutaîna Chandouri, Léa Rivière et autres

Current therapies that target the B-cell receptor pathway or the inhibition of anti-apoptotic proteins do not prevent the progressive forms of chronic lymphocytic leukemia (CLL), have low long-term efficacy and are subject to therapeutic resistance. Deciphering the mechanisms of leukemic cell survival …

fr (code pays fourni par la source)

Extracellular vesicles from Nurse-Like Cells and THP1-derived Type-2 macrophages transfer aggressiveness to chronic lymphocytic leukemia cells

Paul‐François Gallet, I.A. Lea, N. Ratti, Stéphanie Durand et autres

Abstract The resistance of leukemic B cells to cell death is mainly associated with interactions within the tumor microenvironment, where they interact with various types of cells. Within this microenvironment, CLL B cells produce and bind cytokines, growth factors, and microvesicles. In …

fr (code pays fourni par la source)

Involvement of prohibitins in an oncogenic protein complex in Chronic Lymphocytic Leukemia

Paul‐François Gallet, I.A. Lea, Valar Franklin, Clive S. D’Santos et autres

Abstract Prohibitins (PHB1 and PHB2) are highly conserved and ubiquitously expressed proteins that are mainly localized in the mitochondria. They have been reported to have multiple functions, which can vary depending on their cellular localization and cell type. They are implicated in …

fr (code pays fourni par la source)

Use of high-plex data provides novel insights into the temporal artery processes of giant cell arteritis

Simon Parreau, Elsa Molina, Stéphanie Dumonteil, Radjiv Goulabchand et autres

Objective: spatial profiling of molecules involved in the temporal arteries of GCA patients and controls. Furthermore, we performed pharmacogenomic network analysis to identify potential treatment targets. Methods: Using human formalin-fixed paraffin-embedded temporal artery biopsy samples (GCA, n = 9; controls, n = …

fr, us (code pays fourni par la source)

POS0091 USE OF HIGH-PLEX DATA REVEALS NOVEL INSIGHTS INTO THE TEMPORAL ARTERY OF GIANT CELL ARTERITIS

Simon Parreau, Elsa Molina, Stéphanie Dumonteil, Radjiv Goulabchand et autres

nl, fr, us (code pays fourni par la source)

Étude transcriptomique spatiale d’artère temporale : nouvelles informations sur le processus de l’artérite à cellules géantes

Simon Parreau, Elsa Molina, Stéphanie Dumonteil, Radjiv Goulabchand et autres

fr, us (code pays fourni par la source)

Evaluation of Tsunami Inundation in the Plain of Martil (North Morocco): Comparison of Four Inundation Estimation Methods

Elise Basquin, Apolline El Baz, Jacques Sainte-Marie, Alain Rabaute et autres

sk, fr, us, Maroc (code pays fourni par la source)

Detection of Glycosylated Markers From Cancer Stem Cells With ColoSTEM Dx Kit for Earlier Prediction of Colon Cancer Aggressiveness

Sabrina Blondy, Stéphanie Durand, Aurélie Lacroix, Niki Christou et autres

Nowadays, colon cancer prognosis still difficult to predict, especially in the early stages. Recurrences remain elevated, even in the early stages after curative surgery. Carcidiag Biotechnologies has developed an immunohistochemistry (IHC) kit called ColoSTEM Dx, based on a MIX of biotinylated plant …

fr (code pays fourni par la source)

CD20 expression, TrkB activation and functional activity of diffuse large B cell lymphoma-derived small extracellular vesicles

Marine Aitamer, Hussein Akil, Chantal Vignoles, Maud Branchaud et autres

fr (code pays fourni par la source)