Ruey Leng Loo

Sentence-Level Five-Class Classification of Food-Disease Relationships in Biomedical Abstracts: A Comparative Evaluation of Large Language Models

Andong Zhu, Qinliang Dai, Qiao He, Zachary D’Alonzo et autres

Synthesizing evidence on food-disease relationships is critical for advancing nutrition science, yet manual curation cannot keep pace with the rapid expansion of the biomedical literature. This study evaluates large language model (LLM)-based approaches for sentence‑level classification of food-disease relationships in PubMed abstracts. …

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Dietary Patterns and Cognitive Decline in Older Adults: Findings from the Western Australia Memory Study

Carolina Blagojevic Castro, Samantha L. Gardener, Farzana Jahan, Juliana Chen et autres

Background: Preventive strategies, including adherence to specific dietary patterns, have received increasing attention as approaches to reduce cognitive decline and dementia risk. However, findings remain inconsistent, partly due to differences in dietary assessment methods, cognitive outcomes, and THE consideration of genetic susceptibility …

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A Reporting Guideline for Observational Studies in Metabolomic Epidemiology: Explanation and Elaboration of the Strobe-MetEpi Checklist

Rachel Kelly, Stacey Reinke, Georgia Lorentzen, Anastasia Chrysovalantou Chatziioannou et autres

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Detection of Phosphite Fungicide in Persea americana Fruits Using Nuclear Magnetic Resonance (NMR) Spectroscopy at 400 and 80 MHz

Andrés Felipe Puentes Bernal, Yimin Wang, Philipp Nitschke, Samuele Sala et autres

High Resolution Image Download MS PowerPoint Slide Nuclear magnetic resonance (NMR) spectroscopy is widely adopted for assessing biochemical composition in agriculture. This study evaluated the feasibility of 400 MHz NMR to detect biochemical differences in Hass avocados grown under conventional ( N …

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Corrigendum to “Unravelling inulin molecules in food sources using a matrix-assisted laser desorption/ionization magnetic resonance mass spectrometry (MALDI-MRMS) pipeline” [Food Res. Int. 184 (2024) 114276]

Sung‐Tong Chin, Berin A. Boughton, Melvin C. L. Gay, Alyce C. Russell et autres

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Multi-Platform Global Profiling and Polyphenol Quantification: Combining Ion Mobility, High-Resolution MS and NMR Workflows

Yimin Wang, Andrés Felipe Puentes Bernal, Melvin C. L. Gay, Andrea Steck et autres

1 H NMR-Based Quantitative Lipoprotein Measurement Cross-Validation with Enzymatic Methods Applied to the OMNI-Heart Dietary Intervention Study

Andong Zhu, Reika Masuda, Philipp Nitschke, Gengjie Jia et autres

High Resolution Image Download MS PowerPoint Slide Nuclear magnetic resonance (NMR) spectroscopy is increasingly employed in research to quantify lipoprotein subfractions, offering potential utility in clinical diagnostics, particularly for cardiovascular risk assessment. However, the independent validation of proprietary NMR-based lipoprotein profiling methods …

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NMR spectroscopy-derived index for the nutritional assessment of extra virgin olive oils based on fatty acids profiling

Charlotte E. Rowley, Zora Singh, Andrea Steck, Birk Schuetz et autres

The nutritional benefits of Extra Virgin Olive Oils (EVOOs) depend on their chemical composition. Currently, there is no simple way to compare the health benefits of different EVOOs based on their fat profiles. Samples from Australia and four Mediterranean countries (N = …

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Analytical quality control in targeted lipidomics: Evaluating the performance of commercial plasma as a surrogate for pooled study samples

Alanah Grant-St James, Alex J. Lee, Julien Wist, Ferdous Ahmed Sohel et autres

BACKGROUND: Pooled quality control (PQC) samples are the gold standard for data quality monitoring in metabolic phenotyping studies. Typically composed of equal parts from all study samples, PQCs can be challenging to generate in large cohorts or when sample volumes are low. …

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Comparison of the effects of three healthy diets on the 112 lipoprotein subclass profiles using a nuclear magnetic resonance-based metabolomics approach

Ruey Leng Loo, Russell G. Jones, Erskine J. Holmes

Diet is a key modifiable factor for improving suboptimal lipoprotein profiles and reducing cardiovascular disease (CVD) risk(1). Dietary patterns like the Dietary Approaches to Stop Hypertension (DASH) or the Mediterranean Diet, with varying macronutrient components, have shown positive effects on total cholesterol …

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Development of an innovative nutritional score for extra virgin olive oil: bridging the gap in edible oil evaluation

A. Escabor, Charlotte Rowley, Elaine C. Holmes, Ruey Leng Loo

Current nutritional rating systems, like the health star rating, help consumers understand the nutritional value of food and were designed in an effort to combat obesity. However, these systems have limitations, especially for edible oils, which vary widely in composition(1). Coupled with …

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Diversity in metabolic profiles in response to dietary interventions

Charlotte E. Rowley, Elaine C. Holmes, Gary Steven Frost, Ruey Leng Loo et autres

Understanding individual variability to dietary interventions is emerging as an important consideration in dietary interventions. Prior research has demonstrated ranging success of interventions. For example, Gardner and colleagues (2007) compared 4 weight loss diets in participants over a 12-month period(1), noting the …

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