2026
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OpenAlex
Yadarat Baljay, Rangsiman Soonthornchaiya, Lisa Kirk Wiese
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2026
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OpenAlex
Lycia Tramujas Vasconcellos Neumann, Simin Mahinrad, Erin Abner, Soo Borson et autres
Abstract The field of Alzheimer's disease and related dementias (AD/ADRD) is undergoing a transformative shift with a better understanding of disease biology, biomarker‐based diagnostics, and disease‐modifying therapies. Yet, these advancements risk exacerbating existing disparities in diagnosis and care. The 2024 Alzheimer's Association …
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2026
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OpenAlex
Deirdre O'Shea, Devi Dhanekula, Swati Kumar, Lily Wang et autres
INTRODUCTION: Epigenetic assays may support non-invasive dementia risk stratification; community views on willingness and implementation remain under-characterized. METHODS: In a survey of 425 adults ≥50 years old, we assessed the willingness for a hypothetical epigenetic test, implementation preferences, reactions to a high-risk …
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2026
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OpenAlex
Magdalena Ioana Tolea, Beth King, Candy Wilson, Bianca Tolea et autres
Early detection of Alzheimer’s disease and related dementias is needed in rural areas, which experience increased cognitive risks. Rural multiculturally diverse residents, providers, educators and students participated in ORCHID, a quasi-experimental, dementia-focused study. Only 36% of patients in the provider intervention group …
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2026
article
OpenAlex
K. D. Slater, Bonnie Nadyne Young, Bonne Ford, Susana B. Adamo et autres
Abstract Ambient air pollution remains a leading environmental risk factor for morbidity and mortality in the U.S, though most research is conducted in urban areas. Our study assessed how sociodemographic factors indicative of social vulnerability were associated with smoke from agricultural burns …
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2025
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OpenAlex
Lilah M. Besser, Madeleine Tourelle, Diana Mitsova, Janet K. Holt et autres
BACKGROUND: Studies have demonstrated that detrimental neighborhood environments (e.g., low greenspace access) are associated with poorer brain health outcomes including Alzheimer's disease and related dementia (ADRD) risk. However, these studies generally have focused on urban populations. Few studies have focused on rural …
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2025
article
OpenAlex
Juyoung Park, Christine L. Williams, Janet K. Holt, Lisa Kirk Wiese
BACKGROUND: Social isolation (SI) is strongly associated with accelerated cognitive decline, yet comprehensive data are lacking among older adults in rural communities, particularly those who are racially/ethnically diverse and economically disadvantaged. The purpose of this study was to examine the impact of …
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2025
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OpenAlex
Ayse Malatyali, Tom Cidav, Rui Xie, Ladda Thiamwong et autres
BACKGROUND: Approximately one in four older adults in the United States experience social isolation, and many report feeling lonely. Although social isolation and loneliness are associated with an increased risk of cognitive impairment and dementia, it is unclear how this association differs …
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2025
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OpenAlex
Christine L. Williams, Lisa Kirk Wiese, Janet K. Holt, Lilah M. Besser
BACKGROUND: Previous research has shown that cognitive function often declines in mid to late life however, rural and ethnoracial minority groups are more likely to experience conditions that contribute risk of ADRD. Our participants from five rural communities surrounding Lake Okeechobee, FL …
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2025
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OpenAlex
James E Galvin, Deborah M Germaine, Claudia Moore, Jennifer A. Jeanty et autres
Abstract Background Over the next 20 years, the number of people over 65 and 85 years old is expected to grow by 62% and 84%, respectively. 1 The older adult population in the US is also becoming more diverse. By 2050, the …
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2025
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OpenAlex
Lisa Kirk Wiese, Heather R. Fuller, Cassandra D. Ford
Abstract Though rural U.S. counties comprise 85% of the “older-age counties,” where more than 20% of residents are >65, innovative interventions to minimize the age-related risk of dementia are not well established. This symposium offers advances in assessment, recruitment, data collection, and …
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2025
article
OpenAlex
Lisa Kirk Wiese, James Galvin, Jennifer Lingler, Ishan Canty Williams et autres
Abstract Rurality confers a heightened risk for Alzheimer’s disease and related dementias (ADRD). Recent demographic shifts have fueled rural, small-town growth, reshaping the composition of rural communities with increased representation of older and racially and ethnically diverse individuals, whose ADRD risk is …
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