Accès ouvert
2025
article
OpenAlex
Jianan Wang, Doris Yang, Icey Zhang, Meiyan Liu
Cardiovascular disease (CVD) remains a highly prevalent condition globally; there were 626 million prevalent cases of CVD in 2023 globally.[1] As well, mental health conditions are widespread. According to new data released by the World Health Organization, more than 1 billion people …
cn, th
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Accès ouvert
2025
article
OpenAlex
Chuan Hong, Jun Wen, Harrison G. Zhang, Vidul Ayakulangara Panickan et autres
Long COVID poses a significant disease burden globally, but its heterogeneous presentation and unreliable coding practices render it difficult to study. Developing efficient phenotyping algorithms is crucial to enabling risk prediction and effective management of Long COVID. We introduce the LAbel-efficienT Long …
us
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Accès ouvert
2025
article
OpenAlex
Ismail Laher, Carolyn Canfield, Meiyan Liu, Icey Zhang et autres
The practice of medicine relies on the love of humanity. In the race for efficiency and innovation, physicians can often overlook the personal circumstances behind the data and presentation of the patient they are treating. Physicians should be focused on treating the …
ca, cn
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Accès ouvert
2025
article
OpenAlex
Jun Jiang, Doris Yang, Icey Zhang
Cardiovascular diseases (CVDs) are the leading cause of death globally. An estimated 17.9 million people died from CVDs in 2019, representing 32% of all global deaths.[1] The Global Burden of Diseases, Injuries, and Risk Factors Study indicated that ischemic heart disease, ischemic …
cn
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Accès ouvert
2024
article
OpenAlex
Doris Yang, Doudou Zhou, Steven Cai, Gan Zi-ming et autres
Background: Cohort studies contain rich clinical data across large and diverse patient populations and are a common source of observational data for clinical research. Because large scale cohort studies are both time and resource intensive, one alternative is to harmonize data from …
us, sg
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Accès ouvert
2024
article
OpenAlex
Mengyan Li, Xiaoou Li, Kevin Pan, Alon Geva et autres
Electronic Health Record (EHR) systems are particularly valuable in pediatrics due to high barriers in clinical studies, but pediatric EHR data often suffer from low content density. Existing EHR code embeddings tailored for the general patient population fail to address the unique …
us
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Accès ouvert
2024
article
OpenAlex
Shanshan Deng, Xinjun Lu, Xue Wang, Binyong Liang et autres
TBX3 behaves as a tumor suppressor or oncoprotein across cancer. However, TBX3 function remains undetermined in intrahepatic cholangiocarcinoma (iCCA), a deadly primary liver malignancy with few systemic treatment options. This study sought to investigate the impact of TBX3 on iCCA. We found …
us, cn, it, de
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Accès ouvert
2024
article
OpenAlex
Monika Maripuri, Andrew Dey, Jacqueline Honerlaw, Chuan Hong et autres
BACKGROUND: Post-COVID-19 condition (colloquially known as "long COVID-19") characterized as postacute sequelae of SARS-CoV-2 has no universal clinical case definition. Recent efforts have focused on understanding long COVID-19 symptoms, and electronic health record (EHR) data provide a unique resource for understanding this …
us, au
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Accès ouvert
2024
article
OpenAlex
Michael V. Vitiello, Doris Yang, Meiyan Liu
FOREWORD Disordered sleep can negatively impact both physical and mental health. It is no exaggeration to say that sleep disturbance affects all aspects of people’s everyday lifes. Sleep research is steadily clarifying the full nature of sleep relationships with health. Prof. Michael …
us, cn
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Accès ouvert
2024
preprint
OpenAlex
Mengyan Li, Xiaoou Li, Kevin Pan, Alon Geva et autres
Abstract The wealth of valuable real-world medical data found within Electronic Health Record (EHR) systems is particularly significant in the field of pediatrics, where conventional clinical studies face notably high barriers. However, constructing accurate knowledge graphs from pediatric EHR data is challenging …
us
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Accès ouvert
2023
dataset
OpenAlex
Rama Shankar, Mingdian Tan, Yueqi Zhang, Benjamin Green et autres
The morbidity of Hepatocellular carcinoma (HCC) is highest in individuals with chronic liver diseases (CLD). However, the effects of cell composition on the progression of CLDs to HCC remain elusive. To gain a better understanding of the spatial distribution of cells and …
us
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Accès ouvert
2023
dataset
OpenAlex
Rama Shankar, Mingdian Tan, Yueqi Zhang, Benjamin Green et autres
The morbidity of Hepatocellular carcinoma (HCC) is highest in individuals with chronic liver diseases (CLD). However, the effects of cell composition on the progression of CLDs to HCC remain elusive. To gain a better understanding of the spatial distribution of cells and …
us
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