Spatial Transcriptomics in HCC

Résumé fourni par la source

The morbidity of Hepatocellular carcinoma (HCC) is highest in individuals with chronic liver diseases (CLD). However, the effects of cell composition on the progression of CLDs to HCC remain elusive. To gain a better understanding of the spatial distribution of cells and their interactions, we created spatial transcriptome data from two HCC and their normal adjacent FFPE tissues using the 10x visium platform. We processed the data using cellRanger and mapped it to the Human Hg38 reference genome with GRCh38.p3 annotation. All data generated by cellRanger is provided here

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