Adam W. Anderson

Tissue Microstructural Heterogeneity Revealed by MR Microscopy

Bibek Dhakal, Benjamin M. Hardy, Xiaoyu Jiang, Adam W. Anderson et autres

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DeepFixel: crossing white‑matter fiber identification through spherical convolutional neural networks

Adam M. Saunders, Lucas W. Remedios, Elyssa M. McMaster, Gaurav Rudravaram et autres

ms per voxel). We introduce DeepFixel, a spherical convolutional neural network approximation for this nonlinear optimization. We model the probability distribution of fibers as a spherical mesh with higher angular resolution than a truncated spherical harmonic representation. To validate DeepFixel, we compare …

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DeepFixel: crossing white‑matter fiber identification through spherical convolutional neural networks

Adam M. Saunders, Lucas W. Remedios, Elyssa M. McMaster, Gaurav Rudravaram et autres

The nature and interpretation of BOLD signals in white matter - A review

John C. Gore, Ming Li, Kurt G. Schilling, Lei Xu et autres

This review summarizes selected recent findings demonstrating the dependence of blood oxygenation level dependent (BOLD) signals in white matter (WM) on tissue microstructure, composition, vascular properties and metabolism, as well as their relationships to fMRI signals within gray matter (GM) networks. BOLD …

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White-Matter BOLD Mediates Time-Varying Cortico-Cortical Functional Connectivity

Lyuan Xu, Yurui Gao, Muwei Li, Zhongliang Zu et autres

Functional connectivity (FC) measurements in the brain using BOLD fMRI have largely focused on correlations between gray-matter (GM) BOLD signals, ignoring the possible relevance of white-matter (WM) in delineating neural networks. We first employed a tract-informed mediation framework to test whether WM …

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A practical prescription for magnetic resonance microscopy in a horizontal bore magnet

Bibek Dhakal, Benjamin M. Hardy, Adam W. Anderson, Mark D. Does et autres

Magnetic resonance microscopy (MRM) produces high spatial resolution proton images of biological tissues, plants, and porous media, revealing microstructural details and contrast unattainable by other means. A major challenge in MRM is the low signal-to-noise ratio at high spatial resolutions, as smaller …

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Longitudinal measures of monkey brain structure and activity through adolescence predict cognitive maturation

Junda Zhu, Clément M. Garin, Xue-Lian Qi, Anna Machado et autres

In humans and other primates, adolescence is associated with improvement in cognitive abilities and with changes in brain structure and connectivity. However, how these changes affect neural activity underlying cognitive performance remains unknown. Here we conducted a multilevel, longitudinal study of monkey …

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Microstructural Heterogeneity of Tissues Revealed by High-Resolution MR Microscopy at 15.2 T

Bibek Dhakal, Benjamin Maurice Hardy, Adam W. Anderson, Mark D. Does et autres

Motivation: To identify the spatial limit of fast exchange on proton relaxation in excised tissues by measuring how relaxation rate depends on water content at different resolutions. Goal(s): To map T1 and M0 variations within a section across resolutions using MR microscopy. …

Low-Cost and Detunable Wireless Resonator Glasses for Enhanced Eye MRI with Concurrent High-Quality Whole-Brain MRI.

Ming‐Chun Lu, Xiaoyue Yang, Jason H. Moore, Pingping Li et autres

Purpose: To develop and evaluate a wearable wireless resonator glasses design that enhances eye MRI signal-to-noise ratio (SNR) without compromising whole-brain image quality at 7 T. Methods: maps were measured in a head/shoulder phantom, and SNR maps were obtained in both phantom …

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Cortical modulation of resting state BOLD signals in white matter

Zhaohua Ding, Lyuan Xu, Yurui Gao, Yu Zhao et autres

Magnetic resonance images of normal brains were analyzed in order to clarify the relationship of resting state BOLD signals in white matter to cortical neural activity. We quantified the degree to which spontaneous activities in the cortex, which are reflected in low …

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SPT-SLIM: Line-Intensity Mapping Pathfinder on the South Pole Telescope

Adam W. Anderson

The Shirokoff Line-Intensity Mapper (SPT-SLIM) is a mm-wavelength, superconducting on-chip spectrometer observing redshifted CO in the 2mm atmospheric window using the 10-meter South Pole Telescope (SPT). The instrument was recently deployed for the first time during the 2024-2025 austral summer season at …

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Functional contrast across the gray-white matter boundary

Muwei Li, Lyuan Xu, Soyoung Choi, Yuanyuan Qin et autres

Functional magnetic resonance imaging studies have traditionally focused on gray matter, overlooking white matter despite growing evidence that functional blood oxygenation-level dependent effects also occur there. In particular, functional coupling across the gray-white matter boundary, an interface between local and global processing, …

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