Accès ouvert
2024
article
OpenAlex
Li-Ting Kao, Tsung-Ying Yang, Wei‐Chun Hung, Wei-Te Yang et autres
Recently, the high proportion of methicillin-resistant Staphylococcus aureus infections worldwide has highlighted the urgent need for novel antibiotics to combat this crisis. The recent progress in computational techniques for use in health and medicine, especially artificial intelligence (AI), has created new and …
tw, jp
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Accès ouvert
2022
article
OpenAlex
Tien‐Ching Lee, Huiting Chen, I‐Chun Tai, Li-Ting Kao et autres
Large bone defects may develop fracture nonunion, leading to disability and psychosocial burdens. Bone grafting with anabolic agents is a good autografting alternative. Simvastatin, as a cholesterol-lowering agent worldwide, is proven to enhance osteogenesis. Considering its dose-dependent adverse effects, we developed a …
tw
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Accès ouvert
2021
article
OpenAlex
Tsung-Ying Yang, Ya‐Ju Hsieh, Li-Ting Kao, Guan Hong Liu et autres
Imipenem-relebactam is a new β-lactam and β-lactamase inhibitor combination to treat carbapenem-resistant gram-negative bacteria infections. However, difference in carbapenem resistant mechanisms existed with geographic variations. To evaluate the susceptibility of imipenem-relebactam to 660 carbapenem-nonsusceptible Enterobacteriaceae isolates in Taiwan and to identify the …
tw
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Accès ouvert
2020
article
OpenAlex
Tsung-Ying Yang, Ya‐Ju Hsieh, Li-Ting Kao, Guan-Hong Liu et autres
Increasing carbapenem resistance rates worldwide underscored the urgent need of novel antimicrobials. Ceftazidime–avibactam and aztreonam–avibactam combinations are developed to combat carbapenem resistance, but biological and geographic variations must be considered for antibiotic susceptibility patterns varied. Thus, we sought to assess the susceptibilities …
tw
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