Romy Skusa

Bacterial factors required for biofilm formation in Staphylococcus epidermidis are linked to contact activation

Annika Rademacher, Katharina Ekat, Romy Skusa, Lotte Scharnagl et autres

Staphylococcus epidermidis is a leading cause of device-associated bloodstream infections, where biofilm formation contributes to persistence in direct contact with host plasma. While extracellular matrix components are central to biofilm development, their functional consequences at the host–pathogen interface remain incompletely understood. Here, …

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Introducing “Rapid phage susceptibility testing” (RPST): an accelerated lytic phage activity test for routine diagnostic laboratories within eight hours

Romy Skusa, Juliane Kohlen, Andreas Podbielski, Philipp Warnke

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Proof-of-Concept Standardized Approach Using a Single-Disk Method Analogous to Antibiotic Disk Diffusion Assays for Routine Phage Susceptibility Testing in Diagnostic Laboratories

Romy Skusa, Justus Groß, Juliane Kohlen, Clemens Schafmayer et autres

Application of bacteriophages in clinical therapies is attractive due to increasing rates of isolation of multidrug-resistant bacteria worldwide. As the phage effect is highly specific, prior susceptibility testing of target bacteria is mandatory. Of note, established standards are lacking. In this research, …

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Fatale neurologische Nebenwirkung einer Anti-CD20-Antikörper-Therapie

Kathie Schmidt, Romy Skusa, Annette Großmann

Progressive multifocal leukoencephalopathy (PML) is a rare, often fatal infection of the central nervous system caused by reactivation of John Cunningham virus (JCV). The case of a 59-year-old woman presenting with neurological disorders after treatment of her relapsed lymphoma with rituximab, among …

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Local Treatment of Driveline Infection with Bacteriophages

Anja Püschel, Romy Skusa, Antonia Bollensdorf, Justus Groß

Drive line infections (DLI) are common infectious complications after left ventricular assist devices (LVAD) implantation. In case of severe or persistent infections, when conservative management fails, the exchange of the total LVAD may become necessary. We present a case of successful treatment …

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Cervical necrotizing fasciitis of odontogenic origin

Romy Skusa, Lichun Zhang

Imaging and Clinical Parameters for Distinction between Infected and Non-Infected Fluid Collections in CT: Prospective Study Using Extended Microbiological Approach

Christopher Skusa, Romy Skusa, Moritz Wohlfarth, Philipp Warnke et autres

The aim of this investigation was to evaluate predictive CT imaging features and clinical parameters to distinguish infected from sterile fluid collections. Detection of infectious agents by advanced microbiological analysis was used as the reference standard. From April 2018 to October 2019, …

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Bacteriophages for the Treatment of Graft Infections in Cardiovascular Medicine

Simon Junghans, Sebastián V. Rojas, Romy Skusa, Anja Püschel et autres

Bacterial infections of vascular grafts represent a major burden in cardiovascular medicine, which is related to an increase in morbidity and mortality. Different factors that are associated with this medical field such as patient frailty, biofilm formation, or immunosuppression negatively influence antibiotic …

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How to Handle CT-Guided Abscess Drainages in Microbiological Analyses? Sterile Vials vs. Blood Culture Bottles for Transport and Processing

Romy Skusa, Christopher Skusa, Moritz Wohlfarth, Andreas Hahn et autres

The aim of this investigation was to compare microbiological analyses of 100 computed tomography-guided drainages from infectious foci (thoracic, abdominal, musculoskeletal), transported and analyzed by two widely established techniques, that are (i) sterile vials or (ii) inoculated blood culture bottles. The mean …

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Expertise Allgemein- und Viszeralchirurgie Oberer Gastrointestinaltrakt

Arnulf H. Hölscher, Stefan Mönig, Hans‐Joachim Meyer, Salah‐Eddin Al‐Batran et autres

Comparison of the etiological relevance of Staphylococcus haemolyticus and Staphylococcus hominis

Hagen Frickmann, Andreas Hahn, Romy Skusa, Nils Mund et autres

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Molecular epidemiology of multidrug-resistant bacteria isolated from Libyan and Syrian patients with war injuries in two Bundeswehr hospitals in Germany

Hagen Frickmann, Thomas Köller, Ralf Matthias Hagen, Klaus-Peter Ebert et autres

Introduction: We assessed the molecular epidemiology of multidrug-resistant bacteria colonizing or infecting war-injured patients from Libya and Syria who were treated at the Bundeswehr hospitals Hamburg and Westerstede, Germany. Methods: Enterobacteriaceae and Gram-negative rod-shaped nonfermentative bacteria with resistance against third-generation methoxyimino cephalosporins …

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