Naomi Uemura

Comparative Analysis of Gastric Epithelial Neoplasm of Fundic‐Gland Mucosa Lineage: Histopathological Features of Background Gastric Mucosa

Ryo Watanabe, Tomoyuki Yada, Takashi Oide, Miki Yoshinobu et autres

ABSTRACT Aims Gastric epithelial neoplasm of fundic‐gland mucosa lineage (GEN‐FGML) has been increasingly recognized in recent years; however, few studies have investigated the histopathology of the background gastric mucosa surrounding the lesion. This study clarifies the histopathological features of the background gastric …

Clinical Features of Invasive Gastric Cancer Developed After Helicobacter pylori Eradication During Regular Endoscopic Surveillance

Akiko Sasaki, Junko Fujisaki, Masaaki Kobayashi, Ken Namikawa et autres

OBJECTIVES: Gastric cancer (GC) may be diagnosed after Helicobacter pylori eradication, sometimes with submucosal invasion; however, its clinical features on regular endoscopic surveillance remain unclear. This study evaluated invasive GC's characteristics after H. pylori eradication during regular endoscopic surveillance by comparing them …

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Incidental secondary finding of a fundic gland-type adenocarcinoma in ESD specimen: a case report

Yugo Kawasaki, Tomoyuki Yada, Ryo Watanabe, Masaaki Mino et autres

An 80-year-old man with a history of Helicobacter pylori eradication therapy underwent esophagogastroduodenoscopy, and a flat elevated lesion measuring 5 mm with discoloration and vascular dilation was noted on the gastric fornix. Endoscopic biopsy revealed adenocarcinoma of the fundic gland-type (GA-FG), and …

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Multi-biome analysis identifies distinct gut microbial signatures and their crosstalk in ulcerative colitis and Crohn’s disease

Shintaro Akiyama, Suguru Nishijima, Yasushi Kojima, Moto Kimura et autres

The integrative multi-kingdom interaction of the gut microbiome in ulcerative colitis (UC) and Crohn's disease (CD) remains underinvestigated. Here, we perform shotgun metagenomic sequencing of feces from patients with UC and CD, and healthy controls in the Japanese 4D cohort, profiling bacterial …

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Minocycline-Induced Acute Pancreatitis With Cyst Formation in a Young Man

Keita Odaka, Katsunori Sekine, Tomoyuki Yada, Masaaki Mino et autres

An 18-year-old male, diagnosed with urethritis and treated with minocycline for six days, presented to our hospital complaining of abdominal pain and nausea. Blood tests and contrast-enhanced computed tomography (CT) showed severe acute pancreatitis. Based on his medical history, blood tests, and …

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Clinical epidemiology of the endoscopic, laparoscopic, and surgical resection of malignant gastric tumors in Japan, 2014–2021: a retrospective study using open data from a national claims database

Akahito Sako, Tomoyuki Yada, Keiichi Fujiya, Ryo Nakashima et autres

BACKGROUND: Gastric cancer is a common malignancy with a high incidence in East Asia. Gastric resection ranges from endoscopic resection to open total gastrectomy. However, nationwide data are lacking. METHODS: This observational study analyzed data from the publicly accessible National Database of …

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Vonoprazan as a Long-term Maintenance Treatment for Erosive Esophagitis: VISION, a 5-Year, Randomized, Open-label Study

Naomi Uemura, Yoshikazu Kinoshita, Ken Haruma, Ryoji Kushima et autres

BACKGROUND & AIMS: Acid secretion inhibitors are associated with hypergastrinemia, which can lead to gastric mucosal changes. Potassium-competitive acid blockers, such as vonoprazan, are more potent than proton pump inhibitors, but long-term safety data are lacking. METHODS: In this phase IV, randomized …

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Incidental leiomyoma discovered and resected during endoscopic submucosal dissection for early gastric cancer

Kai Oshima, Tomoyuki Yada, Ryo Watanabe, Yugo Kawasaki et autres

An 85-year-old man underwent esophagogastroduodenoscopy (EGD), revealing a 50-mm erythematous, depressed lesion with partial elevation in the gastric cardia on the lesser curvature. Endoscopic biopsy confirmed a diagnosis of adenocarcinoma, and subsequently, endoscopic submucosal dissection (ESD) was performed. During dissection, a centrally …

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IS ENDOSCOPIC TRANSPAPILLARY GALLBLADDER STENTING AN EFFECTIVE TREATMENT?

Katsunori Sekine, Keita Odaka, Tomoyuki Yada, Yugo Kawasaki et autres

IS ENDOSCOPIC TRANSPAPILLARY GALLBLADDER STENTING AN EFFECTIVE TREATMENT?

Katsunori Sekine, Keita Odaka, Tomoyuki Yada, Yugo Kawasaki et autres

Identifying intraductal papillary mucinous neoplasm patients needing surveillance by assessing mortality risks related to comorbidities versus pancreatic cancer : A large long-term cohort study

Katsunori Sekine, Tomoyuki Yada, Naomi Uemura, Naoyoshi Nagata et autres

prognostic significance with an unfavorable outcome in SDC patients.

Multicenter study of invasive gastric cancer detected after 10 years of Helicobacter pylori eradication in Japan: Clinical, endoscopic, and histopathologic characteristics

Masaaki Kobayashi, Junko Fujisaki, Ken Namikawa, Shu Hoteya et autres

Abstract Objectives Gastric cancer can be diagnosed even in patients long after Helicobacter pylori eradication. Most cases involve intramucosal lesions; however, some are invasive and require surgery. To clarify appropriate long‐term surveillance methods, this study compared invasive gastric cancer diagnosed ≥10 and …

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