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Profil bibliographique

Simon S. Rahal

Informations fournies par OpenAlex. Research Africa ne déduit ni nationalité, ni poste, ni coordonnées personnelles.

5Publications signalées
45Citations signalées
2Affiliations récentes

Les institutions déclarées

Les domaines associés

Traumatic Brain Injury and Neurovascular DisturbancesNeuroinflammation and Neurodegeneration MechanismsPleural and Pulmonary DiseasesUltrasound in Clinical ApplicationsEpilepsy research and treatment

Les publications récentes

2023 article OpenAlex

Pharmacologic Toll-like receptor 4 inhibition skews toward a favorable A1/A2 astrocytic ratio improving neurocognitive outcomes following traumatic brain injury

Mahmoud G. El Baassiri, Simon S. Rahal, William B. Fulton, Chhinder Pal Sodhi et autres

BACKGROUND: Astrocytes are critical neuroimmune cells that modulate the neuroinflammatory response following traumatic brain injury (TBI) because of their ability to acquire neurotoxic (A1) or neuroprotective (A2) phenotypes. Using C34, a novel pharmacologic Toll-like receptor (TLR) 4 inhibitor, we explored their respective …

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15 citations The Journal of Trauma: Injury, Infection, and Critical Care
2023 article OpenAlex

Infiltrating anti-inflammatory monocytes modulate microglial activation through toll-like receptor 4/interferon–dependent pathways following traumatic brain injury

Mahmoud G. El Baassiri, Young Hak Chun, Simon S. Rahal, William B. Fulton et autres

BACKGROUND: Traumatic brain injury (TBI) is the leading cause of morbidity and mortality in the pediatric population. Microglia and infiltrating monocyte-derived macrophages are crucial immune cells that modulate the neuroinflammatory response following TBI. Using C34, a novel pharmacologic toll-like receptor 4 inhibitor, …

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10 citations The Journal of Trauma: Injury, Infection, and Critical Care

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