Min Li

Statistical power analysis of standard cardiovascular safety pharmacology studies in telemetry implanted dogs and nonhuman primates

Shanshan An, Min Li, Miao He

cn (code pays fourni par la source)

Impact of E-Coach chronic disease management model combined with the WeChat platform on self-management ability in hypertension patients

Xianzhi Lv, Pinnan Zhao, J Q Chen, Min Li

Objective Hypertension remains a major global health challenge requiring effective long-term management. This study evaluated the impact of the E-Coach chronic disease management model integrated with WeChat on self-management capabilities in patients with hypertension. Methods This was a single-center randomized controlled trial. …

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Risk factors and airway management of postoperative retropharyngeal hematoma following anterior cervical spine surgery: a retrospective study

Yang Tian, Xixi Jia, Gang Li, Yongzheng Han et autres

BACKGROUND: Postoperative retropharyngeal hematoma (RH) is a potentially life-threatening complication of anterior cervical spine surgery (ACSS). Difficult intubation frequently arises during airway management in patients with RH, presenting substantial challenges in clinical practice. This retrospective cohort study aimed to (1) identify risk …

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Short-term follow-up results of ultra-low-dose radiotherapy for indolent B-cell lymphoma

Min Li, Ran Peng, Ping Yang, Fang Bao et autres

Abstract Objective: To evaluate the short-term efficacy and safety of ultra-low-dose radiotherapy (4 Gy) in patients with indolent B-cell lymphoma. Materials and Methods: A retrospective analysis was conducted on 14 patients with indolent B-cell lymphoma treated with ultra-low-dose radiotherapy at our institution …

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A Dual Action of Everolimus in Ulcerative Colitis: Blocking CLEC4E‐Driven Inflammation and Remodeling the Gut Microbiota‐Metabolite Axis

Jing Chen, Min Li, Wenyan Sun, Yuyun Chen et autres

ABSTRACT Ulcerative colitis (UC) is a chronic inflammatory bowel disease with limited treatment options. This study investigated the therapeutic potential and mechanisms of Everolimus (Eve), a selective mTORC1 inhibitor, in experimental UC. Dextran sulfate sodium (DSS)‐induced colitis mice were used to assess …

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Risk factors for emergency cesarean delivery in patients with placenta accreta spectrum: a multicenter retrospective cohort study

Min Li, Hongyuan Zhang, Xiao Song, Liang Li et autres

Background Pregnant women with placenta accreta spectrum (PAS), particularly those with placenta increta or placenta percreta, undergoing emergency cesarean section are at a high risk of excessive intraoperative hemorrhage and related complications. This study aimed to evaluate maternal and neonatal outcomes and …

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[A case of hepatitis B surface antigen clearance achievement based on the combination of interferon and intermittent consolidation therapy].

Wen Deng, Shouyang Wang, Wei Cao, Yao Xie et autres

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Xiao‐Jie‐An Capsule Alleviates Uterine Fibroids by Modulating Oestrogen–Progesterone Balance and Reducing Inflammatory Response

Ying Yi, Jihan Liu, Shanshan Ju, Meiyu Shen et autres

Uterine fibroids (UF) are benign tumours composed of smooth muscle cells and fibrous connective tissue. UF are common among women aged 30-50 years and often present with symptoms such as anaemia, pelvic pain and bladder dysfunction. Xiao-Jie-An Capsule (XJA), a traditional Chinese …

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Mendelian randomization analysis of gut microbiota-immune cell interactions in malignant neoplasm of nasopharynx

Qicong Chen, Gang Wang, Jingcheng Shu, Weiwei Miao et autres

Observational studies have suggested associations among the gut microbiome, immune cells, and the risk of malignant neoplasms of nasopharynx. However, the causality of these relationships remains unclear. Thus, we conducted multiple Mendelian Randomization analyses to estimate the causal association of gut microbiota …

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Kushenol I combats ulcerative colitis via intestinal barrier preservation and gut microbiota optimization

Xudong He, Min Li, Xianbo Zuo, Heyuan Michael Ni et autres

BACKGROUND: Kushenol I (KSCI) exhibits potential anti-inflammatory and antioxidant activities. However, its therapeutic effects and mechanisms in ulcerative colitis (UC) remain unclear. AIM: To investigate the therapeutic effects and mechanisms of KSCI in alleviating UC. METHODS: Therapeutic targets for KSCI in treating …

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The role of FAK in renal collecting duct in the progression from acute kidney injury to chronic kidney disease

Cai Gao, Jinzhao He, Yiming Wang, Guangying Shao et autres

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Anthrahydroquinone-2,6-Disulfonate Restores Lung Function in COPD Through Keap1/Nrf2 Pathway Activation

Jun Chen, Jiadong Zhang, Nan Li, Yi Yang et autres

Objective: Chronic obstructive pulmonary disease (COPD), the third leading cause of death globally, is strongly driven by oxidative damage, contributing to lung function decline and high mortality. Despite advances in understanding oxidative stress in COPD pathogenesis, effective strategies to mitigate oxidative damage …

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