Thiago Beduschi

244.7: Restoration of endothelial BMP9 signaling during ex vivo lung perfusion improves marginal donor lung recovery.

Logan Langerude, Blake Gill, Satish Nadig, Bryan Taylor et autres

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Liver transplantation for valproic acid-induced acute liver failure in POLG mutation-related mitochondrial disease with cardiac and neurological involvement

Rohan V. Mehta, Alfonso Santos, Ashutosh Shukla, Amer Belal et autres

Mitochondria are intracellular organelles essential for cellular energy production through oxidative phosphorylation, a process mediated by the mitochondrial respiratory chain (MRC). The MRC comprises >90 proteins encoded by both mitochondrial DNA (mtDNA) and nuclear DNA. The POLG gene encodes the catalytic subunit …

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Use of aspirin for prevention of hepatic artery thrombosis after liver transplantation: A systematic review and meta-analysis

Raul Valério Ponte, Amanda Gabriela Batista dos Santos, Maria Fernanda Moura de Lima, Priscila Ferreira de Lima Souza et autres

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The United States Experience With Combined Lung+Liver Transplantation

Liam R. Kugler, Ahmet Bilgili, Griffin P. Stinson, Tyler Kashuv et autres

Background: Combined lung+liver transplant (CLLT) is a rare procedure for patients with end-stage lung and liver failure, but has recently gained traction, with many academic centers performing CLLT for the first time. This study describes the state of CLLT in the United …

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USE OF ASPIRIN FOR PREVENTION OF HEPATIC ARTERY THROMBOSIS AFTER LIVER TRANSPLANTATION: A SYSTEMATIC REVIEW AND META-ANALYSIS

Raul Valério Ponte, Priscila Souza, Amanda dos Santos, Marisa Lopes Lima et autres

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Portal Vein Thrombosis, Management and Approaches in Liver Transplantation: A Narrative Review

João Bernardo Sancio Rocha Rodrigues, Raul Valério Ponte, Thiago Beduschi, Daiki Soma

This review delves into the complexities of managing portal vein thrombosis (PVT) in the context of liver transplantation (LT). PVT, which is a common finding in cirrhotic livers, can significantly jeopardize LT outcomes. Here, we explore the incidence, underlying mechanisms, and comprehensive …

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Successful Liver Transplantation and Long-Term Survival in Patients with Perioperative Heparin-Induced Thrombocytopenia and Thromboembolic Complications

Daiki Soma, Abbas Shahmohammadi, Lucas Ernani, Rushi Shah et autres

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Achieving Excellence in Simultaneous Pancreas-Kidney Transplantation: A Single-Center Analysis

Georgios Vrakas, C. Theocharopoulos, Ashraf El-hinnawi, C. Lenas et autres

Purpose: Inequities in subspecialty pediatric outcomes due to adverse social drivers of health (SDOH) are well described; limited data exist in the pediatric heart transplant population. We aimed to describe the frequency of a modifiable SDOH, household material hardship ([HMH], food, housing, …

A Single-Center Experience With En-Bloc Combined Heart+Liver Transplantation: Analysis of Eight Cases, Including Two Heart+Liver+Kidney Transplants

Matthew S. Purlee, Thiago Beduschi, Jeffrey Phillip Jacobs, Werviston De Faria et autres

ObjectivesReview our clinical experience with eight patients at the University of Florida undergoing En-bloc combined heart+liver transplantation (ECH + LTX).MethodsContinuous variables are reported as median (interquartile range = IQR) and categorical variables are reported as N (%).ResultsEight patients underwent ECH + LTX …

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Tacrolimus dosing in liver transplant recipients using phenotypic personalized medicine: A phase 2 randomized clinical trial

Jeffrey Khong, Megan Lee, Curtis R. Warren, Un Bi Kim et autres

Tacrolimus is the most commonly used immunosuppression drug after solid organ transplantation; however, its dosing is challenging due to substantial inter-individual variability, often resulting in blood levels that deviate from the target therapeutic range. We explored whether a dynamically customized, phenotypic-outcome-guided drug …

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889: PSOAS-MELD: A NEW MODEL TO BETTER PREDICT OUTCOMES IN LIVER TRANSPLANT PATIENTS

Tayna D. Latortue, Andrew Kleehammer, Hannah L. Zuercher, Katarina Pittman et autres

Comparing the Outcomes of Combined Heart-Liver Transplant Recipients from DCD and Non-DCD Donors: An Analysis Using the UNOS Database

Lindsey M. Brinkley, Liam R. Kugler, Werviston De Faria, G.J. Peek et autres

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