Na Tian

Re-authoring the altered self: the impact of a three-phase narrative nursing intervention on body image and distress in oral squamous cell carcinoma

Na Tian, Q Y Liu, Huijie Wang, Qigen Fang

Background Locally advanced oral squamous cell carcinoma (OSCC) and its surgical treatment precipitate profound body image disturbance and psychological distress. With the increasing adoption of neoadjuvant immunochemotherapy (NICT), patients now experience fundamentally different treatment trajectories, yet the psychological implications of this paradigm …

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PVN CRF Neurons Regulate Migraine‐Like Allodynia by Activating CRFR2 on Spinal Trigeminal Caudalis Glutamatergic Neurons (Adv. Sci. 29/2026)

Jiang Bian, Xiao‐Long Wang, Li Yin, Wei Wei et autres

Chronic Migraine Chronic NTG injection pathologically activates PVNCRF neurons, leading to excessive release of CRF neuropeptides into the downstream nucleus SP5C. The elevated CRF neuropeptides aberrantly activate CRFR2 receptors on SP5CGlu neurons, resulting in hyperexcitability of these neurons and ultimately triggering migraine-like …

PVN CRF Neurons Regulate Migraine‐Like Allodynia by Activating CRFR2 on Spinal Trigeminal Caudalis Glutamatergic Neurons

Jiang Bian, Xiao-Long Wang, Li Yin, Wei Wei et autres

ABSTRACT Migraine is a prevalent and debilitating neurological disorder with poorly understood neural mechanisms. Here, we characterize a hypothalamic‐trigeminal pathway involved in the regulation of migraine‐like allodynia. Using a combination of monosynaptic circuit, fiber photometry‐based calcium imaging, and behavioral assays in a …

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GALM Alleviates Aβ Pathology and Cognitive Deficit Through Increasing ADAM10 Maturation in a Mouse Model of Alzheimer’s Disease

Na Tian, Junjie Li, Xiuyu Shi, Mingliang Xu et autres

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CSTB accelerates the progression of hepatocellular carcinoma via the ERK/AKT/mTOR signaling pathway

Weiyi Zhu, Xiangjun Dong, Na Tian, Zijuan Feng et autres

Hepatocellular carcinoma (HCC) is a significant contributor to global cancer-related deaths, leading to high mortality rates. However, the pathogenesis of HCC remains unclear. In this research, by the bioinformatics data analysis, we found that elevated CSTB expression correlated with advanced disease and …

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Optimization of food deprivation and sucrose preference test in SD rat model undergoing chronic unpredictable mild stress

Liwen He, Li Zeng, Na Tian, Yi Li et autres

Abstract Background The chronic unpredictable mild stress (CUMS) model has long been considered the best model for exploring the pathophysiological mechanisms underlying depression. However, there are no widely recognised standards for strategies for modeling and for behavioral testing. The present study aimed …

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GABA consumption during early pregnancy impairs endometrial receptivity and embryo development in mice

Na Tian, Hao Liang, Wenping Luo, Xiaojie Wang et autres

Abstract γ‐Aminobutyrate (GABA) is commonly used as a food supplement and a health care product by young females, due to its positive roles in relieving stress, alleviating anxiety, and improving sleep. However, its recommended daily dose in different products varies widely. Besides, …

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Erratum: Urine-derived stem cells accelerate the recovery of injured mouse hepatic tissue.

Chaoqun Hu, Yun He, Shuyu Fang, Na Tian et autres

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MicroRNA-7 as a potential therapeutic target for aberrant NF-κB-driven distant metastasis of gastric cancer

Tingbo Ye, Meihua Yang, Daochao Huang, Xin Wang et autres

BACKGROUND: Dysregulated miR-7 and aberrant NF-κB activation were reported in various human cancers. However, the expression profile, clinical relevance and dysregulated mechanism of miR-7 and NF-κB RelA/p65 in human gastric cancers (GC) metastasis remain largely unknown. This study is to investigate the …

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Positive regulation of placentation by L-amino acid transporter-1 (lat1) in pregnant mice.

Xiaojie Wang, Wenping Luo, Dongmei Tan, Hao Liang et autres

results in disorder of placental anatomical structure in mid-late pregnancy. These results suggest that lat1 might play an important role in mouse placentation progress.

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MSX2 Induces Trophoblast Invasion in Human Placenta

Hao Liang, Qian Zhang, Junjie Lu, Genling Yang et autres

Normal implantation depends on appropriate trophoblast growth and invasion. Inadequate trophoblast invasion results in pregnancy-related disorders, such as early miscarriage and pre-eclampsia, which are dangerous to both the mother and fetus. Msh Homeobox 2 (MSX2), a member of the MSX family of …

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