Nicola Kumar

Comparing outcomes using low‐dose apixaban and anti‐Xa monitoring and vitamin K antagonists in patients with renal replacement therapy

J. Bartoli-Abdou, Alexander Thomas Cohen, Lucy Vernon, Victoria Collings et autres

Background Guidelines recommend oral anticoagulation for stroke prevention in atrial fibrillation and secondary prevention of venous thromboembolism. Outside the United States, apixaban is unlicensed for use in patients with end‐stage renal disease (ESRD) receiving renal replacement therapy (RRT). Aim To compare thrombotic …

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Comparable Outcomes Using Low-Dose Apixaban and Anti-Xa Monitoring and Vitamin-K Antagonists in Patients with Renal Replacement Therapy

John Bartoli-Abdou, Ander Cohen, Lucy Vernon, Victoria Collings et autres

Background: Guidelines recommend the use of oral anticoagulation for stroke prevention in atrial fibrillation and secondary prevention of venous thromboembolism. Outside the USA, apixaban is contraindicated for use in patients with end stage renal disease (ESRD) receiving renal replacement therapy (RRT). Aim: …

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Outcome and effect of vaccination in SARS-CoV-2 Omicron infection in hemodialysis patients: a cohort study

Damien R. Ashby, Ben Caplin, Richard Corbett, Elham Asgari et autres

BACKGROUND: Hemodialysis patients are at high risk of Covid-19, though vaccination has significant efficacy in preventing and reducing the severity of infection. Little information is available on disease severity and vaccine efficacy since the dissemination of the Omicron variant. METHODS: In a …

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Severity of COVID-19 after Vaccination among Hemodialysis Patients

Damien R. Ashby, Ben Caplin, Richard Corbett, Elham Asgari et autres

BACKGROUND AND OBJECTIVES: Patients receiving hemodialysis are at high risk from coronavirus disease 2019 (COVID-19) and demonstrate impaired immune responses to vaccines. There have been several descriptions of their immunologic responses to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination, but few …

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Risk of COVID-19 Disease, Dialysis Unit Attributes, and Infection Control Strategy among London In-Center Hemodialysis Patients

Ben Caplin, Damien R. Ashby, Kieran McCafferty, Richard Hull et autres

Background and objectives Patients receiving in-center hemodialysis treatment face unique challenges during the coronavirus disease 2019 (COVID-19) pandemic, specifically the need to attend for treatment that prevents self-isolation. Dialysis unit attributes and isolation strategies that might reduce dialysis center COVID-19 infection rates …

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IgG SARS-CoV-2 Antibodies Persist at Least for 10 Months in Patients on Hemodialysis

Caroline Dudreuilh, Tayeba Roper, Cormac P. Breen, Paramit Chowdhury et autres

See Commentary on Page 1761 See Commentary on Page 1761 Patients with kidney failure have an impaired response to vaccination,1Khan S.F. Bowman B.T. Vaccinating the patient with ESKD.Clin J Am Soc Nephrol. 2019; 14: 1525-1527Crossref PubMed Scopus (5) Google Scholar and an …

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Delivering Dialysis During the COVID-19 Outbreak: Strategies and Outcomes

Tayeba Roper, Nicola Kumar, Timothy Lewis-Morris, Vicki Moxham et autres

Coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and carries a fatality rate of 1.0% to 13.5% in confirmed cases.1,2 Infection is mainly through droplets reaching the eyes, mouth, or nose of an individual, and transmission …

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De-isolation of COVID-19–positive hemodialysis patients in the outpatient setting: a single-center experience

Caroline Dudreuilh, Nicola Kumar, Vicki Moxham, Carolyn J. Hemsley et autres

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Incidence, risk factors, and outcomes of stroke post‐transplantation in patients receiving a steroid sparing immunosuppression protocol

Michelle Kay Willicombe, Nicola Kumar, Dawn Goodall, Candice Clarke et autres

Corticosteroid use after transplantation is associated with an increased incidence of cardiovascular events and death. Cerebrovascular disease is a common cause of morbidity and mortality post-renal transplantation; however, a dedicated analysis of cerebrovascular disease in recipients of a steroid sparing protocol has …

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Low Incidence of Cardiac Death After Renal Transplantation in Patients Undergoing Pre-Emptive Coronary Angiography and Revascularisation.

Dimitrios-Anestis Moutzouris, Chris Baker, Nicola Kumar, Michelle Kay Willicombe et autres

Purpose Cardiovascular disease is one of the commonest and potentially treatable causes of death with a functioning renal allograft. All our high-risk patients, including those >50 years of age are offered pre transplant coronary angiography and revascularisation, if flow-limiting disease is identified …

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New Onset Diabetes After Kidnet Transplantation Despite the Use of a Steroid-Sparing Regime Is Associated With a Higher Mortality From Cardiac Causes.

Dimitrios-Anestis Moutzouris, Chris Baker, Nicola Kumar, Michelle Kay Willicombe et autres

Purpose New-onset diabetes after transplantation [NODAT] is associated with increased cardiovascular risk and reduced patient survival. We have also shown that patients who develop NODAT, despite the use of a steroid sparing immunosuppressive regime have reduced patient survival. In this study, we …

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AA Amyloidosis in a patient with glycogen storage disorder and progressive chronic kidney disease

J Dick, Nicola Kumar, Catherine J. Horsfield, Satishkumar A. Jayawardene

Type 1 glycogen storage diseases (GSD) are inherited metabolic diseases caused by defects in the activity of the glucose-6-phosphate transporter. We present the case of a 40-year-old male with glycogen storage disease type 1b (GSD1b) who was referred to our nephrology service …

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