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Conor C. Horgan, Mads S. Bergholt, Anika Nagelkerke, May Zaw Thin et autres
This system thus achieves effective theranostic performance, providing a promising new avenue towards the clinical realisation of theranostics.
gb (code pays fourni par la source)
Conor C. Horgan, Mads S. Bergholt, Anika Nagelkerke, May Zaw Thin et autres
Theranostics, the combination of diagnosis and therapy, has long held promise as a means to achieving personalised precision cancer treatments. However, despite its potential, theranostics has yet to realise significant clinical translation, largely due the complexity and overriding toxicity concerns of existing …
gb (code pays fourni par la source)
Thomas E. Whittaker, Anika Nagelkerke, Valeria Nele, Ulrike Kauscher et autres
ABSTRACT It has been demonstrated that some commonly used Extracellular Vesicle (EV) isolation techniques can lead to substantial contamination with non‐EV factors. Whilst it has been established that this impacts the identification of biomarkers, the impact on apparent EV bioactivity has not …
gb (code pays fourni par la source)
Ulrike Kauscher, Jelle Penders, Anika Nagelkerke, Margaret N. Holme et autres
Extracellular vesicles (EVs) are secreted by the vast majority of cells and are being intensively studied due to their emerging involvement in a variety of cellular communication processes. However, the study of their cellular uptake and fate has been hampered by difficulty …
gb, nl, se (code pays fourni par la source)
Conor C. Horgan, Anika Nagelkerke, Thomas E. Whittaker, Valeria Nele et autres
Extracellular vesicles (EVs) are biologically derived nanovectors important for intercellular communication and trafficking, yet understanding of their underlying biological mechanisms remains poor. Advances have been hampered by both the complex biological origins of EVs and a lack of suitable imaging techniques. Here, …
gb (code pays fourni par la source)
Conor C. Horgan, Anika Nagelkerke, Thomas E. Whittaker, Valeria Nele et autres
Extracellular vesicles (EVs) are biologically-derived nanovectors important for intercellular communication and trafficking. As such, EVs show great promise as disease biomarkers and therapeutic drug delivery vehicles. However, despite the rapidly growing interest in EVs, understanding of the biological mechanisms that govern their …
gb, hr (code pays fourni par la source)
Limor Zwi‐Dantsis, Charles W. Winter, Ulrike Kauscher, Arianna Ferrini et autres
Extracellular vesicles (EVs) represent a promising cell-free alternative for treatment of cardiovascular diseases. Nevertheless, the lack of standardised and reproducible isolation methods capable of recovering pure, intact EVs presents a significant obstacle. Additionally, there is significant interest in investigating the interactions of …
ch, gb, us (code pays fourni par la source)
Valeria Nele, Margaret N. Holme, Ulrike Kauscher, Michael R. Thomas et autres
Liposomes are well-established systems for drug delivery and biosensing applications. The design of a liposomal carrier requires careful choice of lipid composition and formulation method. These determine many vesicle properties including lamellarity, which can have a strong effect on both encapsulation efficiency …
gb, se (code pays fourni par la source)
Valeria Nele, Margaret N. Holme, Ulrike Kauscher, Michael R. Thomas et autres
Research data supporting the paper: Nele V. et al., Langmuir (2019), DOI: 10.1021/acs.langmuir.8b04256
gb (code pays fourni par la source)
Valeria Nele, Margaret N. Holme, Ulrike Kauscher, Michael R. Thomas et autres
Research data supporting the paper: Nele V. et al., Langmuir (2019), DOI: 10.1021/acs.langmuir.8b04256
gb (code pays fourni par la source)
Jelle Penders, Isaac J. Pence, Conor C. Horgan, Mads S. Bergholt et autres
Comprehensive single nanoparticle analysis of synthetic drug delivery systems, as well as natural occurring particles such as Extracellular Vesicles (EVs), is still a major challenge in the field, and is necessary to enhance their successful design, screening and study towards translational application. …
gb (code pays fourni par la source)
Conor C. Horgan, Mads S. Bergholt, Anika Nagelkerke, Isaac J. Pence et autres
Theranostic approaches to cancer management offer the possibility of tailoring treatments to individual patients or tumours. However, the development of theranostic nanoparticles optimally suitable for both diagnostic and therapeutic modalities to achieve this is challenging. Here we demonstrate an alternative nanoparticle-free theranostic …
gb (code pays fourni par la source)
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