Fuqian Zhao

Comparative analysis of routine peripheral blood parameters in influenza and COVID-19 patients: a retrospective study

Mingquan Shang, Xin Ma, Qiang Xu, Hongmei Niu et autres

Influenza and COVID-19 are major causes of respiratory illness, and differentiating between them remains a clinical challenge when molecular testing is unavailable. This retrospective study evaluated whether routine peripheral blood parameters could aid in this differentiation. Data from 848 participants (225 influenza, …

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Resolving Incompatible Blood Cross-Matching: The Role of 37°C Water Bath in Transfusion Safety

Jun-Ling Han, Fuqian Zhao, Yu Rong, Xiang Li et autres

Background: Incompatible cross-matching at room temperature can delay critical blood transfusions. We report that red cells from patients requiring blood transfusion agglutinated after cross-matching at room temperature, but changed from agglutination to dispersion after a water bath at 37°C. The aim was …

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Peripheral blood tumor marker levels can indicate the location of lung cancer metastasis

Jiahao Wang, Xiaobo Wang, Yingjia Mao, Hongmei Niu et autres

Early detection of lung cancer metastasis is of great importance for improving patient survival and reducing the economic and social burden of the disease. Omics analysis is widely used in the screening of tumor markers. However, effective markers that can indicate tumor …

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Chemotherapy drugs do not affect the production of hepatitis B surface antibodies: A case report

Fuqian Zhao, Junling Han, Dao-fu Shen, Rong Yu et autres

Vaccines can stimulate an immune response. However, whether the use of chemotherapy drugs affects the body's production of antibodies after vaccination remains to be studied. This study reports the case of a 49-year-old female patient who first visited Chifeng City Hospital (Chifeng, …

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CD55 may be a new target for colorectal cancer treatment

Qiong Luo, Yingjia Mao, Rong Yu, Fuqian Zhao et autres

In the early stage, our research group injected lentivirus carrying blood type A antigen into tumors as a drug, and the tumor volume of mice was significantly reduced. We speculate that the complement system plays an important role in anti-tumor therapy, but …

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Kerstersia gyiorum infection in a patient with chronic suppurative otitis media identified by whole genome sequencing: a case report

Dao-fu Shen, Wu Zhao, Mingquan Shang, Hao Yu et autres

A 52-year-old female patient suffering from chronic suppurative otitis media had a bacterial strain isolated from her ear swab specimens, which could not be identified using conventional methods, but it was eventually identified as Kerstersia gyiorum via whole genome sequencing (WGS). Antimicrobial …

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Immunotherapy: A new target for cancer cure (Review)

Fuqian Zhao, Dao-fu Shen, Mingquan Shang, Hao Nao Yu et autres

Cancer is the leading cause of death globally and there is a worldwide cancer epidemic. Immunotherapy has emerged as a promising anticancer therapy. In particular, oncolytic viruses destroy cancer cells without destroying normal tissue via viral self‑replication and anti‑tumor immune responses, showing …

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Modulation of IL-37 expression by triptolide and triptonide in THP-1 cells

Lingge He, Zhuangyan Liang, Fuqian Zhao, Lifei Peng et autres

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[The expression of human IL-37 in E.coli and preparation and characterization of mouse anti-IL-37 antibody].

Fuqian Zhao, Suhui He, Lingge He, Miaofen Lin et autres

OBJECTIVE: To construct a prokaryotic expression system for interleukin-37 (IL-37) and prepare its polyclonal antibody. METHODS: The gene encoding mature interleukin-37 (IL-37m) was amplified by PCR and subcloned into prokaryotic expression vector pET28a. Then the recombinant plasmid pET28a/IL-37m was transformed into E.coli …

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A potential approach to antifertility vaccine by expression of sperm membrane peptide in Salmonella.

Ai-jun Gao, Y C Yan, Qian Yang, Fuqian Zhao et autres

A synthetic oligonucleotide, HSD-2a, encoding a peptide segment of the extracellular domain of a human sperm membrane protein, YWK-II, was inserted by blunt-end ligation at the EcoRV site in the hypervariable, antigenically determinant region IV of Salmonella flagellin gene fliC (d). The …