Jiarui Liang

Rapid Generation of Subject‐Specific Human Models With Detailed Tissue Structures for Timely Individualized SAR Assessment

Jiaqi Hu, Jiarui Liang, Fangyong Sun, Yantu Huang et autres

ABSTRACT Purpose To enable the rapid generation of subject‐specific whole‐body anatomical models for patient‐specific prediction of torso–local specific absorption rate (SAR) in MRI. Methods A 6‐s 3D gradient‐echo MRI sequence was used to acquire data within the imaging field of view (FOV). …

cn (code pays fourni par la source)

AAVone: A cost-effective, single-plasmid solution for efficient AAV production with reduced DNA impurities

Rongze Yang, Ngoc Tam Tran, Taylor Chen, Mengtian Cui et autres

transduction efficiency, but a substantial reduction in DNA impurities from plasmid bacterial backbones and a marked reduction in non-functional snap-back genomes. The AAVone system does not pose a risk for generating replication-competent AAV contaminants. Furthermore, the AAVone system requires significantly less DNAs …

ru, us (code pays fourni par la source)

AAVone: A Cost-Effective, Single-Plasmid Solution for Efficient AAV Production with Reduced DNA Impurities

Rongze Yang, Ngoc Tam Tran, Taylor Chen, Mengtian Cui et autres

ABSTRACT Currently, the most common approach for manufacturing GMP-grade adeno-associated virus (AAV) vectors involves transiently transfecting mammalian cells with three plasmids that carry the essential components for production. The requirement for all three plasmids to be transfected into a single cell and …

ru, us, fr (code pays fourni par la source)

Mechanistic basis for the allosteric activation of NADase activity in the Sir2-HerA antiphage defense system

Xiangkai Zhen, Biao Zhou, Zihe Liu, Xurong Wang et autres

Sir2-HerA is a widely distributed antiphage system composed of a RecA-like ATPase (HerA) and an effector with potential NADase activity (Sir2). Sir2-HerA is believed to provide defense against phage infection in Sir2-dependent NAD+ depletion to arrest the growth of infected cells. However, …

cn (code pays fourni par la source)

Transfer Learning-Based YOLOv3 Model for Road Dense Object Detection

Chunhua Zhu, Jiarui Liang, Fei Zhou

Stemming from the overlap of objects and undertraining due to few samples, road dense object detection is confronted with poor object identification performance and the inability to recognize edge objects. Based on this, one transfer learning-based YOLOv3 approach for identifying dense objects …

cn (code pays fourni par la source)

AI Model of Using Stratified Deep Learning to Delineate the Organs at Risk (OARs) for Thoracic Radiation Therapy

X. Ye, Dongsheng Guo, Jun Liu, Jiahao Ge et autres

cn, us, hk (code pays fourni par la source)

CELL BIOLOGY AND SIGNALING

F. Furnari, Tim R. Fenton, D. Nathanson, C. P. de Alberquerque et autres