Accès ouvert
2026
article
OpenAlex
Josué A. Rodríguez-Cordero, Marialena Dorta Avilés, Imilce A. Rodriguez‐Fernandez, Alfredo Ghezzi et autres
While central circuits governing sleep are well-studied, the contribution of signaling from peripheral tissues remains a critical yet less understood aspect of sleep regulation. The highly conserved RNA-binding protein Pumilio (Pum) is a post-transcriptional regulator expressed in multiple tissues that influence systemic …
pr
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Accès ouvert
2025
preprint
OpenAlex
Josué A. Rodríguez-Cordero, Marialena Dorta-Avilés, Imilce A. Rodriguez‐Fernandez, Alfredo Ghezzi et autres
Abstract While central circuits governing sleep are well-studied, the contribution of signaling from peripheral tissues remains a critical yet less understood aspect of sleep regulation. The highly conserved RNA-binding protein Pumilio (Pum) is a post-transcriptional regulator expressed in multiple tissues that influence …
pr
(code pays fourni par la source)
Accès ouvert
2025
preprint
OpenAlex
Yilmaz Berk Koru, Katharina Beer, Angelo Alberto Ruggieri, Josué A. Rodríguez-Cordero et autres
Summary Disruption in gut microbiota during the early postnatal period can disrupt normal neural development and result in long-term behavioral alterations1. Similar to other neural systems, the circadian clock mechanism continues to mature after birth2, yet how microbial disturbances in the early …
pr, de, us, nl
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Accès ouvert
2024
article
OpenAlex
Jenny P. Acevedo‐Gonzalez, Alberto Galindo‐Cardona, Nicolás Fuenzalida‐Uribe, Yarira Ortiz‐Alvarado et autres
Abstract Honey bee, Apis mellifera L. (Hymenoptera: Apidae), colonies and individuals respond variably to disturbances. The response depends on perception and interpretation of stimuli requiring both neural modulation and use of energy. In this study, we examined the role of neural modulation …
pr, ar
(code pays fourni par la source)
Accès ouvert
2024
preprint
OpenAlex
Maria E. Ramirez-Roman, Nicolás Fuenzalida‐Uribe, Genesis Ayala-Santiago, José L. Agosto et autres
Abstract Alcohol exposure is known to trigger homeostatic adaptations in the brain that lead to the development of tolerance and dependence. These adaptations are also believed to be the root of a series of disturbances in sleep patterns that often manifest during …
pr
(code pays fourni par la source)
Accès ouvert
2022
preprint
OpenAlex
Angelo Alberto Ruggieri, Luca Livraghi, James J. Lewis, Elizabeth Evans et autres
Despite insertions and deletions being the most common structural variants (SVs) found across genomes, not much is known about how much these SVs vary within populations and between closely related species, nor their significance in evolution.To address these questions, we characterized the …
pr, pa, us, ca, gb, Soudan du Sud
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Accès ouvert
2022
preprint
OpenAlex
Angelo Alberto Ruggieri, Luca Livraghi, James J. Lewis, Elizabeth Evans et autres
Despite insertions and deletions being the most common structural variants (SVs) found across genomes, not much is known about how much these SVs vary within populations and between closely related species, nor their significance in evolution. To address these questions, we characterized …
pr, pa, us, ca, gb, be
(code pays fourni par la source)
Accès ouvert
2022
preprint
OpenAlex
Jenny P. Acevedo‐Gonzalez, Alberto Galindo‐Cardona, Nicolás Fuenzalida‐Uribe, Alfredo Ghezzi et autres
Abstract Honey bee ( Apis mellifera sp.) colonies and individuals respond variably to disturbances. In this study, we examined the role of neural modulation and metabolism in constitutive and experience-dependent differences in defensive response. We compared brain gene expression in bees of …
pr, ar
(code pays fourni par la source)
Accès ouvert
2022
preprint
OpenAlex
Angelo Alberto Ruggieri, Luca Livraghi, James J. Lewis, Elizabeth Evans et autres
Abstract Despite insertions and deletions being the most common structural variants (SVs) found across genomes, not much is known about how much these SVs vary within populations and between closely related species, nor their significance in evolution. To address these questions, we …
pr, us, ca, gb, pa
(code pays fourni par la source)
Accès ouvert
2021
article
OpenAlex
Amanda Anqueira-González, Jenny P. Acevedo‐Gonzalez, Airined Montes-Mercado, Claudia Irizarry-Hernández et autres
When presented with the choice, Drosophila melanogaster females will often prefer to lay eggs on food containing a significant amount of alcohol. While, in some cases, this behavioral decision can provide a survival advantage to the developing larvae, it can also lead …
pr
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Accès ouvert
2020
article
OpenAlex
Luis A. De Jesús-Olmo, Norma I. Rodríguez-Malavé, Marcelo Francia, Jonathan Alemán-Rios et autres
Recent studies have identified the Drosophila brain circuits involved in the sleep/wake switch and have pointed to the modulation of neuronal excitability as one of the underlying mechanisms triggering sleep need. In this study we aimed to explore the link between the …
pr
(code pays fourni par la source)
Accès ouvert
2019
preprint
OpenAlex
Luis A. De Jesús-Olmo, Norma I. Rodríguez-Malavé, Marcelo Francia, Jonathan Alemán-Rios et autres
Abstract Recent studies have identified the Drosophila brain circuits involved in the sleep/wake switch and have pointed to the modulation of neuronal excitability as one of the underlying mechanisms triggering sleep need. In this study we aimed to explore the link between …
pr
(code pays fourni par la source)