Anna Cohuet

The brain of the female Anopheles gambiae mosquito at spatial and single-cell resolution

Irene Rossi, Cécile Cassan, Johannes Bagnoli, Sümeyye Özhan et autres

Abstract Blood feeding in Anopheles mosquitoes is at the root of all malaria infections in humans and is supported by a range of physiological and behavioral adaptations. Since behavior is orchestrated at the level of the central nervous system, we surveyed the …

fr, nl, gb (code pays fourni par la source)

Effectiveness of a dry season larviciding strategy to complement universal coverage with long-lasting insecticidal nets against malaria: a pragmatic cluster randomised controlled trial in Côte d’Ivoire

Cédric Pennetier, Barnabas Zogo, Bertin N. Tchiekoi, Ludovic P. Ahoua Alou et autres

Background Malaria control has stagnated in several endemic regions despite widespread use of long-lasting insecticidal nets (LLINs). We assessed whether adding dry-season microbial larviciding to LLINs could provide additional malaria control benefit in rural West Africa. Methods We conducted a pragmatic cluster-randomised …

fr, Côte d’Ivoire, Burkina Faso, Bénin, Sénégal (code pays fourni par la source)

Commercial permethrin elicits chemoreceptive responses on different Anopheles gambiae sensory appendages

Sassan Simplice Kambou, Adeline Valente, Philip Agnew, Anna Cohuet et autres

BACKGROUND: For malaria mosquitoes, the ability to detect pyrethroid insecticides before coming into contact with an impregnated surface can be highly advantageous in terms of fitness. Such detection may lead to the development of behavioral modifications that help them to avoid commonly …

fr, Burkina Faso (code pays fourni par la source)

Frequent and genetically diverse Plasmodium vivax relapses contribute to malaria transmission in Cambodia

Jean Popovici, Dynang Seng, Katie Ko, Ágnes Orbán et autres

kh, us, fr (code pays fourni par la source)

MaRNAV-1, an intracellular virus of Plasmodium vivax , is associated with increased parasite transmission and altered host immune response

Dynang Seng, Katie Ko, Ágnes Orbán, Sokleap Heng et autres

Abstract MaRNAV-1 is an RNA virus recently identified in Plasmodium vivax -infected samples, but definitive evidence that it infects the parasite and influences malaria pathogenesis remains unknown. Here, we demonstrate that MaRNAV-1 is an intracellular virus that is present in P. vivax …

kh, us, fr, Éthiopie, sg, au (code pays fourni par la source)

Replication data and R code for: Commercial permethrin elicits chemoreceptive responses on different Anopheles gambiae sensory appendages

Sassan S Kambout, Adeline Valente, Philip Agnew, Anna Cohuet et autres

BACKGROUND For malaria mosquitoes, the ability to detect pyrethroid insecticides before coming into contact with an impregnated surface can be highly advantageous in terms of fitness. Such detection may lead to the development of behavioral modifications that help them to avoid commonly …

fr (code pays fourni par la source)

Pfs230 domain 12 is a potent malaria transmission–blocking vaccine candidate

Maartje R. Inklaar, Roos M. de Jong, Dari F. Da, Lisanne L. Hubregtse et autres

Malaria transmission–blocking vaccines (TBV) target sexual stage parasites that are transmitted to mosquitoes and are critical for spread of the pathogen. The clinically most advanced TBV candidate contains part of the Pro-domain (Pro) and Domain 1 (D1) of Plasmodium falciparum surface protein …

nl, Burkina Faso, jp, Ouganda, fr (code pays fourni par la source)

Permethrin elicits chemoreceptive responses on different Anopheles gambiae sensory appendages

Sassan Simplice Kambou, Adeline Valente, Philip Agnew, Anna Cohuet et autres

ABSTRACT BACKGROUND Non-contact detection of pyrethroid insecticides by malaria mosquitoes has been unveiled and may contribute to the evolution of mosquito behavioral modifications against vector control tools. However, the mechanisms underlying this detection are not yet fully understood. It has been hypothesized …

fr, Burkina Faso (code pays fourni par la source)

Efficacy of non-pyrethroid indoor residual spraying or intensive behaviour change communication in combination with long-lasting insecticidal nets for malaria control in west Africa: a pragmatic, cluster-randomised, controlled trial

Nicolas Moiroux, Issaka Zongo, Serge-Brice Assi, Anthony Somé et autres

BACKGROUND: Since 2015, progress in the control of malaria has stalled owing to multiple factors, including the probable reduced efficacy of long-lasting insecticidal nets (LLINs) caused by insecticide resistance and plateauing LLIN use rates. This study aimed to assess the additional effect …

fr, Burkina Faso, Côte d’Ivoire (code pays fourni par la source)

Pfs230 Domain 12 is a potent malaria transmission-blocking vaccine candidate

Maartje R. Inklaar, Roos M. de Jong, Dari F. Da, Lisanne L. Hubregtse et autres

Abstract Malaria transmission-blocking vaccines (TBV) target sexual stage parasites that are transmitted to mosquitoes and critical for spread of the pathogen. The clinically most advanced TBV candidate contains part of the Pro-domain (Pro) and Domain 1 (D1) of Plasmodium falciparum surface protein …

nl, Burkina Faso, jp, Ouganda, fr (code pays fourni par la source)

Partial clearance of pre-established Plasmodium falciparum infection in mosquitoes by feeding on patients treated with Artemether+Lumefantrine + Atovaquone-Proguanil

Anna Cohuet, Priscilla Adjei-Kusi, Rakiswendé Serge Yerbanga, Thierry Lefèvre et autres

International audience

Non-contact detection of pyrethroids widely used in vector control by Anopheles mosquitoes

Sassan Simplice Kambou, Adeline Valente, Philip Agnew, Domonbabélé François de Sales Hien et autres

Pyrethroids are the most widely used insecticides to control vector borne diseases including malaria. Physiological resistance mechanisms to these insecticides have been well described, whereas those for behavioral resistance remain overlooked. Field data suggest the presence of spatial sensory detection by Anopheles …

fr, Burkina Faso (code pays fourni par la source)