GluN2D-containing NMDA receptors support dentate granule cell excitability, synaptic plasticity, and memory
Coralie Berthoux, Alma Rodenas-Ruano, Laxman Bist, Kaoutsar Nasrallah et autres
N-Methyl-D-aspartate ionotropic glutamate receptors (NMDARs) are crucial for synaptic transmission, long-term plasticity, neuronal activity, and cognition. Consistent with these functions, NMDAR dysfunction is linked to several brain disorders, including Alzheimer's disease, autism, schizophrenia, and depression. NMDARs are tetrameric complexes composed of two …
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bioRxiv (Cold Spring Harbor Laboratory)