Profil bibliographique

John T. Mehl

Informations fournies par OpenAlex. Research Africa ne déduit ni nationalité, ni poste, ni coordonnées personnelles.

34Publications signalées

1020Citations signalées

1Affiliations récentes

Institutions déclarées

Domaines associés

Advanced Proteomics Techniques and ApplicationsMass Spectrometry Techniques and ApplicationsProtein purification and stabilityBiosimilars and Bioanalytical MethodsMonoclonal and Polyclonal Antibodies Research

Publications récentes

Accès ouvert 2024 articleOpenAlex

2023 White Paper on Recent Issues in Bioanalysis: Deuterated Drugs; LNP; Tumor/FFPE Biopsy; Targeted Proteomics; Small Molecule Covalent Inhibitors; Chiral Bioanalysis; Remote Regulatory Assessments; Sample Reconciliation/Chain of Custody (PART 1A – Recommendations on Mass Spectrometry, Chromatography, Sample Preparation Latest Developments, Challenges, and Solutions and BMV/Regulated Bioanalysis PART 1B - Regulatory Agencies' Inputs on Regulated Bioanalysis/BMV, Biomarkers/IVD/CDx/BAV, Immunogenicity, Gene & Cell Therapy and Vaccine)

Mike Baratta, Wenying Jian, Shawna Hengel, Surinder Kaur et autres

12 citationsBioanalysis

2023 articleOpenAlex

2022 White Paper on Recent Issues in Bioanalysis: ICH M10 BMV Guideline & Global Harmonization; Hybrid Assays; Oligonucleotides & ADC; Non-Liquid & Rare Matrices; Regulatory Inputs ( Part 1A – Recommendations on Mass Spectrometry, Chromatography and Sample Preparation, Novel Technologies, Novel Modalities, and Novel Challenges, ICH M10 BMV Guideline & Global Harmonization Part 1B - Regulatory Agencies' Inputs on Regulated Bioanalysis/BMV, Biomarkers/CDx/BAV, Immunogenicity, Gene & Cell Therapy and Vaccine)

Matt Szapacs, Wenying Jian, Daniel S. Spellman, Jennifer Cunliffe et autres

20 citationsBioanalysis

2023 articleOpenAlex

Protein LC-MS Tools for the Next Generation of Biotherapeutic Analyses from Preclinical and Clinical Serum

Nicole A. Schneck, John T. Mehl, John F. Kellie

3 citationsJournal of the American Society for Mass Spectrometry

Accès ouvert 2022 articleOpenAlex

Highly Accurate and Robust Absolute Quantification of Target Proteins in Formalin-Fixed Paraffin-Embedded (FFPE) Tissues by LC–MS

Jie Pu, Chao Xue, Shihan Huo, Qingqing Shen et autres

3 citationsAnalytical Chemistry

2022 articleOpenAlex

Top-Down Characterization and Intact Mass Quantitation of a Monoclonal Antibody Drug from Serum by Use of a Quadrupole TOF MS System Equipped with Electron-Activated Dissociation

John F. Kellie, Nicole A. Schneck, Jason Causon, Takashi Baba et autres

23 citationsJournal of the American Society for Mass Spectrometry

Accès ouvert 2022 articleOpenAlex

Application of Pharmacokinetic/Pharmacodynamic Modeling to Bridge Mouse Antitumor Efficacy and Monkey Toxicology Data for Determining the Therapeutic Index of an Interleukin-10 Fc Fusion Protein

James Loy, Brian Poirson, Yan‐Shan Dai, Surendran Rajendran et autres

2 citationsFrontiers in Pharmacology

2022 articleOpenAlex

An antibody-free platform for multiplexed, sensitive quantification of protein biomarkers in complex biomatrices

Bo An, Timothy W. Sikorski, John F. Kellie, Zhuo Chen et autres

7 citationsJournal of Chromatography A

Accès ouvert 2022 articleOpenAlex

Target-Mediated Drug Disposition Affects the Pharmacokinetics of Interleukin-10 Fragment Crystallizable Fusion Proteins at Pharmacologically Active Doses

Zheng Yang, Surendran Rajendran, Vanessa Spires, Brian Poirson et autres

6 citationsDrug Metabolism and Disposition

Accès ouvert 2022 articleOpenAlex

2021 White Paper on Recent Issues in Bioanalysis: Mass Spec of Proteins, Extracellular Vesicles, CRISPR, Chiral Assays, Oligos; Nanomedicines Bioanalysis; ICH M10 Section 7.1; Non-Liquid & Rare Matrices; Regulatory Inputs ( Part 1A – Recommendations on Endogenous Compounds, Small Molecules, Complex Methods, Regulated Mass Spec of Large Molecules, Small Molecule, PoC & Part 1B - Regulatory Agencies' Inputs on Bioanalysis, Biomarkers, Immunogenicity, Gene & Cell Therapy and Vaccine)

Surinder Kaur, Stephen C. Alley, Matt Szapacs, Amanda Wilson et autres

31 citationsBioanalysis

2021 articleOpenAlex

Quantification of Surrogate Monoclonal Antibodies in Mouse Serum Using LC–MS/MS

John T. Mehl, France Landry, Lorell Discenza, Bogdan Sleczka et autres

2 citationsBioanalysis

2020 articleOpenAlex

Intact Protein Mass Spectrometry for Therapeutic Protein Quantitation, Pharmacokinetics, and Biotransformation in Preclinical and Clinical Studies: An Industry Perspective

John F. Kellie, John C. Tran, Wenying Jian, Barry Jones et autres

31 citationsJournal of the American Society for Mass Spectrometry

2018 articleOpenAlex

Fucosyl monosialoganglioside: Quantitative analysis of specific potential biomarkers of lung cancer in biological matrices using immunocapture extraction/tandem mass spectrometry

Asoka Ranasinghe, John T. Mehl, Celia D’Arienzo, Fizal Nabbie et autres

5 citationsRapid Communications in Mass Spectrometry

Profil ORCID Notice OpenAlex

BNTIC News n’est pas le producteur de ces données. Recherche à la demande dans Crossref, OpenAIRE, DOAJ, Europe PMC, HAL, DataCite, ROR et la Banque mondiale, sans clé ; OpenAlex reste optionnel. Aucun service payant requis, aucune donnée externe enregistrée en base. Sources et limites.