Xiufang Xie

Identification of Clinical Phenotypes in Young Patients with Acute Exacerbations of COPD: A Multicenter Cohort Study.

Jiaqi Pu, Hailong Wei, Huiqing Ge, Huiguo Liu et autres

BACKGROUND: Despite the rising recognition of chronic obstructive pulmonary disease (COPD) in younger adults (20-50 years), the clinical heterogeneity of this population during acute exacerbations (AECOPD) remains undefined, obscuring precision risk stratification and personalized management. METHODS: This study analyzed data from a …

Determinants of fungal infection and hospital readmission risk in interstitial pneumonia with autoimmune features: associations with vitamin D and pirfenidone

Gaodi Yuan, Xiufang Xie, Min Tang, Xiaoli Zheng et autres

Background: Fungal infections significantly compromise the prognosis of patients with interstitial pneumonia with autoimmune features (IPAF). However, the specific immune-related risk factors and their impact on clinical stability remain poorly defined. This study aimed to identify independent predictors for fungal infection and …

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Clinical and prognostic differences in mild to moderate AECOPD with and without emphysema: a 3-year multicenter prospective study

Jiaqi Pu, Mingjing Yu, Hailong Wei, Huiqing Ge et autres

Introduction The prognostic significance of the computed tomography (CT)-defined emphysema phenotype in patients hospitalized with mild-to-moderate acute exacerbation of chronic obstructive pulmonary disease (AECOPD) remains poorly defined. Materials and methods This prospective multicenter cohort study analyzed data from the MAGNET AECOPD Registry. …

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Efficacy, safety, and tolerability of treatments for interstitial lung disease associated with rtoid arthritis: A systematic review and network meta-analysis

Yuwei Hu, Yujie Gan, Min Tang, Xiufang Xie et autres

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Prevalence and clinical correlates of infection in idiopathic inflammatory myopathies: A systematic review and meta-analysis of 14,548 patients

Gaodi Yuan, Xiufang Xie, Min Tang, Xiaoli Zheng et autres

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The impact of systemic corticosteroids guided by blood eosinophil thresholds and rome classification on clinical outcomes in hospitalized AECOPD patients: a multicenter study

Jiaqi Pu, Mingjing Yu, Yuanming Luo, Hailong Wei et autres

This study assessed the efficacy of combining blood eosinophil (EOS) thresholds and Rome classification to guide corticosteroid therapy in hospitalized acute exacerbations of chronic obstructive pulmonary disease (AECOPD) patients. This multicenter study analyzed data from 7 to 111 AECOPD patients, stratified by …

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Limited predictive value of Padua and Caprini scores for venous thromboembolism in AECOPD patients with atrial fibrillation

Jiaqi Pu, Yuanming Luo, Hailong Wei, Huiqing Ge et autres

Venous thromboembolism (VTE) risk is elevated in acute exacerbations of COPD (AECOPD), especially with coexisting atrial fibrillation (AF). However, the Caprini and Padua scores, validated in surgical or general medical populations, may not capture thrombotic risk in AECOPD-AF patients, and their predictive …

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The impact of Candida infection on short-term and long-term outcomes in AECOPD patients: A 3-year multicenter cohort study

Jiaqi Pu, Yuanming Luo, Hailong Wei, Huiqing Ge et autres

OBJECTIVES: The clinical significance of Candida infection in patients with acute exacerbations of chronic obstructive pulmonary disease (AECOPD) remains poorly defined. METHODS: This multicenter cohort study analyzed 11,925 hospitalized AECOPD patients from ten centers in China, grouped by Candida infection status. Subgroups …

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Derivation and Validation of a New Score for Predicting In-Hospital Mortality in Exacerbations of Chronic Obstructive Pulmonary Disease

Lige Peng, Qun Yi, Yuanming Luo, Hailong Wei et autres

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Systemic Immune-Inflammation Index Is Associated with Adverse Outcomes in Patients Hospitalized for AECOPD: A Multicenter Cohort Study

Xueqing Chen, Yuanming Luo, Hailong Wei, Huiqing Ge et autres

INTRODUCTION: Acute exacerbations of chronic obstructive pulmonary disease (AECOPDs) are associated with increased morbidity and mortality. The novel inflammatory biomarker, systemic immune-inflammation index (SII), may have prognostic value. This study aimed to assess the association between SII and short-term and long-term adverse …

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Clinical characteristics and prognosis prediction in patients with AECOPD and type 2 diabetes mellitus: A multicenter observational study

Xiaoqian Li, Qun Yi, Yuanming Luo, Hailong Wei et autres

ObjectivesDiabetes is a common comorbidity in COPD population. This study aimed to explore the impacts of T2DM on clinical characteristics and outcomes of patients with exacerbation of COPD, as well as develop a specified prognostic model for these patients.MethodsAECOPD patients were enrolled …

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Prediction Model of In-Hospital Death for Acute Exacerbation of Chronic Obstructive Pulmonary Disease Patients Admitted to Intensive Care Unit: The PD-ICU Score

Xiaoqian Li, Qun Yi, Yuanming Luo, Hailong Wei et autres

INTRODUCTION: Patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD) admitted to intensive care unit (ICU) are exposed to poor clinical outcomes, and no specific prognostic models are available among this population. We aimed to develop and validate a risk score …

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