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Profil bibliographique

Nobuyuki Kanematsu

Informations fournies par OpenAlex. Research Africa ne déduit ni nationalité, ni poste, ni coordonnées personnelles.

215Publications signalées
3623Citations signalées
1Affiliations récentes

Les institutions déclarées

Les domaines associés

Radiation Therapy and DosimetryAdvanced Radiotherapy TechniquesRadiation Detection and Scintillator TechnologiesParticle physics theoretical and experimental studiesHigh-Energy Particle Collisions Research

Les publications récentes

Accès ouvert 2026 article OpenAlex

ADDRESSING THE LET TRILEMMA IN MULTI-ION THERAPY FOR HEAD AND NECK CANCERS: ROBUSTNESS EVALUATION AND ION SELECTION RATIONALE FOR A PHASE I CLINICAL TRIAL

Takamitsu Masuda, Hiroaki Ikawa, Makoto Shinoto, Masashi Koto et autres

Background and Aims: Boron Neutron Capture Therapy (BNCT) is a targeted radiation therapy, in which boron-10 accumulated in tumor cells is irradiated with neutrons to generate short-range, high linear energy transfer particles that damage tumor cells while sparing surrounding normal tissue.Glioblastoma remains …

us, jp (code pays fourni par la source)

0 citations International Journal of Particle Therapy
2026 article OpenAlex

Robustness of LET d -optimized multi-ion therapy against range and setup uncertainties: evaluation and enhancement with carbon-, oxygen-, and neon-ion beams

Takamitsu Masuda, Hiroaki Ikawa, Makoto Shinoto, Masashi Koto et autres

Abstract Objective. The LET trilemma—an inherent conflict between target dose homogeneity, range robustness, and high dose-averaged linear energy transfer (LET d )—poses a major challenge in treatment optimization. To ensure accurate beam delivery in multi-ion therapy, this study evaluated the effects of …

jp (code pays fourni par la source)

0 citations Physics in Medicine and Biology
2025 article OpenAlex

Neon ion radiotherapy: physics and biology

Stewart Mein, Takamitsu Masuda, Koki Kasamatsu, Taku Nakaji et autres

Abstract Neon ion ( 20 Ne) beam radiotherapy was one of the primary particle therapy candidates investigated during the clinical trials beginning in the 1970s at the Lawrence Berkely National Laboratory (LBNL), which shut down in the early 1990s. Currently, therapeutic neon …

de, jp, cn (code pays fourni par la source)

2 citations Physics in Medicine and Biology
2025 article OpenAlex

Evaluation of diamond and silicon detectors for linear energy transfer measurements of therapeutic helium, carbon, oxygen, and neon ion beams

Taku Inaniwa, Makoto Sakama, Sung Hyun Lee, Taku Nakaji et autres

Abstract Objective. Diamond and silicon detectors are increasingly popular tools for dose-averaged linear energy transfer (LET) in water L ¯ w measurements of therapeutic ion beams. The LET measured in detector materials is linearly scaled to the LET in water using a …

jp, kr, au (code pays fourni par la source)

1 citation Physics in Medicine and Biology
2025 article OpenAlex

Effects of intra-tumoral cellular heterogeneity of oxygen partial pressure on biological effectiveness of hydrogen-, helium-, carbon-, oxygen-, and neon-ion beams

Taku Inaniwa, Takamitsu Masuda, Nobuyuki Kanematsu

Abstract Objective. The tumor microenvironment characterized by heterogeneously organized vasculatures causes intra-tumoral heterogeneity of oxygen partial pressure p at the cellular level, which cannot be measured by current imaging techniques. The intra-tumoral cellular p heterogeneity may lead to a reduction of therapeutic …

jp (code pays fourni par la source)

4 citations Physics in Medicine and Biology

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